Kcnip2 (potassium voltage-gated channel interacting protein 2) - Rat Genome Database

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Gene: Kcnip2 (potassium voltage-gated channel interacting protein 2) Heterocephalus glaber
Analyze
Symbol: Kcnip2
Name: potassium voltage-gated channel interacting protein 2
RGD ID: 18914832
Description: ENCODES a protein that exhibits A-type (transient outward) potassium channel activity (ortholog); calcium ion binding (ortholog); identical protein binding (ortholog); INVOLVED IN action potential (ortholog); clustering of voltage-gated potassium channels (ortholog); membrane repolarization (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; alfentanil pharmacodynamics pathway; ASSOCIATED WITH Cardiac Arrhythmias (ortholog); FOUND IN cytoplasm (ortholog); dendrite (ortholog); Kv4.2-KChIP2 channel complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Kv channel-interacting protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248311,301,598 - 1,319,572 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248311,301,840 - 1,319,487 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
alfentanil pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupivacaine pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway  (ISO)
buprenorphine pharmacodynamics pathway   (ISO)
calcium/calcium-mediated signaling pathway  (ISO)
carvedilol pharmacodynamics pathway  (ISO)
chloroprocaine pharmacodynamics pathway  (ISO)
citalopram pharmacodynamics pathway  (ISO)
cocaine pharmacodynamics pathway  (ISO)
codeine and morphine pharmacodynamics pathway  (ISO)
desipramine pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
diphenoxylate pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
escitalopram pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
ethylmorphine pharmacodynamics pathway  (ISO)
fentanyl pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fluoxetine pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
heroin pharmacodynamics pathway  (ISO)
hydrocodone pharmacodynamics pathway  (ISO)
hydromorphone pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
imipramine pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levacetylmethadol pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
levobupivacaine phgarmacodynamics pathway  (ISO)
levorphanol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
mepivacaine pharmacodynamics pathway  (ISO)
methadone pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nalbuphine pharmacodynamics pathway  (ISO)
naloxone pharmacodynamics pathway  (ISO)
naltrexone pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nicotine pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
oxybuprocaine pharmacodynamics pathway  (ISO)
oxycodone pharmacodynamics pathway  (ISO)
oxymorphone pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
pentazocine pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
prilocaine pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
procaine pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
remifentanil pharmacodynamics pathway  (ISO)
ropivacaine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
tramadol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Kcnip2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248311,301,598 - 1,319,572 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248311,301,840 - 1,319,487 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
KCNIP2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3810101,825,974 - 101,843,800 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl10101,825,974 - 101,843,920 (-)EnsemblGRCh38hg38GRCh38
GRCh3710103,585,731 - 103,603,557 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610103,575,721 - 103,593,667 (-)NCBINCBI36Build 36hg18NCBI36
Build 3410103,575,721 - 103,593,667NCBI
Celera1097,324,471 - 97,342,415 (-)NCBICelera
Cytogenetic Map10q24.32NCBI
HuRef1097,216,464 - 97,234,410 (-)NCBIHuRef
CHM1_110103,869,314 - 103,887,271 (-)NCBICHM1_1
T2T-CHM13v2.010102,709,458 - 102,727,289 (-)NCBIT2T-CHM13v2.0
Kcnip2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391945,780,785 - 45,804,948 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1945,780,278 - 45,804,500 (-)EnsemblGRCm39 Ensembl
GRCm381945,792,346 - 45,816,422 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1945,791,839 - 45,816,061 (-)EnsemblGRCm38mm10GRCm38
MGSCv371945,868,160 - 45,890,293 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361945,846,981 - 45,869,114 (-)NCBIMGSCv36mm8
Celera1946,555,638 - 46,577,688 (-)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1938.75NCBI
Kcnip2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81254,590,172 - 254,614,437 (-)NCBIGRCr8
mRatBN7.21244,641,147 - 244,664,939 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1244,641,150 - 244,664,874 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1252,782,586 - 252,806,733 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01259,480,725 - 259,504,561 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01252,132,599 - 252,156,275 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01265,549,610 - 265,573,393 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1265,549,593 - 265,573,409 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl1262,892,545 - 262,916,361 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01270,337,725 - 270,361,519 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41251,008,676 - 251,032,402 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1240,448,191 - 240,472,276 (-)NCBICelera
Cytogenetic Map1q54NCBI
Kcnip2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554858,467,207 - 8,470,950 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554858,468,117 - 8,472,220 (+)NCBIChiLan1.0ChiLan1.0
KCNIP2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v28113,712,657 - 113,730,573 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan110113,717,971 - 113,735,894 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01098,428,619 - 98,446,581 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.110101,899,898 - 101,918,691 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10101,899,898 - 101,918,691 (-)Ensemblpanpan1.1panPan2
KCNIP2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12814,409,526 - 14,425,641 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2814,409,526 - 14,425,641 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2814,578,242 - 14,596,662 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02814,877,733 - 14,896,184 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2814,859,845 - 14,896,560 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12814,424,193 - 14,442,591 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02814,463,755 - 14,482,179 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02814,596,080 - 14,614,481 (-)NCBIUU_Cfam_GSD_1.0
Kcnip2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721332,337,576 - 32,371,125 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366003,940,813 - 3,961,803 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366003,940,806 - 3,974,455 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KCNIP2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14112,857,062 - 112,876,439 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114112,857,058 - 112,876,469 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214122,709,372 - 122,726,785 (-)NCBISscrofa10.2Sscrofa10.2susScr3
KCNIP2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1994,854,024 - 94,873,655 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl994,855,403 - 94,873,312 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604855,930,976 - 55,951,582 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027218   ⟹   ENSHGLP00000026979
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248311,301,598 - 1,319,572 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027219   ⟹   ENSHGLP00000026980
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248311,302,824 - 1,319,572 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027220   ⟹   ENSHGLP00000026981
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248311,302,824 - 1,319,485 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027221   ⟹   ENSHGLP00000026982
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248311,302,824 - 1,319,485 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027222   ⟹   ENSHGLP00000026983
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248311,302,824 - 1,316,344 (-)Ensembl
RefSeq Acc Id: XM_004866374   ⟹   XP_004866431
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,319,486 (-)NCBI
RefSeq Acc Id: XM_004866377   ⟹   XP_004866434
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,319,486 (-)NCBI
RefSeq Acc Id: XM_004866379   ⟹   XP_004866436
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,316,339 (-)NCBI
RefSeq Acc Id: XM_004866380   ⟹   XP_004866437
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,319,448 (-)NCBI
RefSeq Acc Id: XM_013066155   ⟹   XP_012921609
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,319,148 (-)NCBI
RefSeq Acc Id: XM_021245585   ⟹   XP_021101244
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,301,840 - 1,319,487 (-)NCBI
RefSeq Acc Id: XM_021245587   ⟹   XP_021101246
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,306,192 (-)NCBI
RefSeq Acc Id: XM_021245588   ⟹   XP_021101247
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248311,302,824 - 1,319,487 (-)NCBI
RefSeq Acc Id: XP_021101244   ⟸   XM_021245585
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021101247   ⟸   XM_021245588
- Peptide Label: isoform X7
RefSeq Acc Id: XP_004866434   ⟸   XM_004866377
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004866431   ⟸   XM_004866374
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004866437   ⟸   XM_004866380
- Peptide Label: isoform X5
RefSeq Acc Id: XP_012921609   ⟸   XM_013066155
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004866436   ⟸   XM_004866379
- Peptide Label: isoform X4
- UniProtKB: G5CAG3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021101246   ⟸   XM_021245587
- Peptide Label: isoform X6
Ensembl Acc Id: ENSHGLP00000026982   ⟸   ENSHGLT00000027221
Ensembl Acc Id: ENSHGLP00000026981   ⟸   ENSHGLT00000027220
Ensembl Acc Id: ENSHGLP00000026979   ⟸   ENSHGLT00000027218
Ensembl Acc Id: ENSHGLP00000026980   ⟸   ENSHGLT00000027219
Ensembl Acc Id: ENSHGLP00000026983   ⟸   ENSHGLT00000027222


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019185 Ensembl, ENTREZGENE
  ENSHGLG00100017930 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027219 ENTREZGENE
  ENSHGLT00000027220 ENTREZGENE
  ENSHGLT00000027221 ENTREZGENE
  ENSHGLT00000027222 ENTREZGENE
  ENSHGLT00100062166 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-dom_pair UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/TrEMBL
  Recoverin UniProtKB/TrEMBL
NCBI Gene Kcnip2 ENTREZGENE
PANTHER KV CHANNEL-INTERACTING PROTEIN 2 UniProtKB/TrEMBL
  PTHR23055 UniProtKB/TrEMBL
Pfam EF-hand_5 UniProtKB/TrEMBL
  EF-hand_7 UniProtKB/TrEMBL
PRINTS RECOVERIN UniProtKB/TrEMBL
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0AAX6Q390_HETGA UniProtKB/TrEMBL
  A0AAX6Q6C6_HETGA UniProtKB/TrEMBL
  A0AAX6Q6F8_HETGA UniProtKB/TrEMBL
  A0AAX6QIL2_HETGA UniProtKB/TrEMBL
  A0AAX6RTW2_HETGA UniProtKB/TrEMBL
  A0AAX6RVE6_HETGA UniProtKB/TrEMBL
  G5CAG3 ENTREZGENE, UniProtKB/TrEMBL