Fstl3 (follistatin like 3) - Rat Genome Database

Name: Fstl3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Fstl3 (follistatin like 3) Heterocephalus glaber

Analyze

Symbol:

Fstl3

Name:

follistatin like 3

RGD ID:

18914321

Description:

ENCODES a protein that exhibits activin binding (ortholog); fibronectin binding (ortholog); INVOLVED IN adrenal gland development (ortholog); cellular response to metal ion (ortholog); hematopoietic progenitor cell differentiation (ortholog); ASSOCIATED WITH cerebral creatine deficiency syndrome (ortholog); cyclic hematopoiesis (ortholog); genetic disease (ortholog); FOUND IN extracellular space (ortholog); neuron projection terminus (ortholog); nucleoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

follistatin-related protein 3

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FSTL3 (follistatin like 3)	NCBI	Ortholog
Mus musculus (house mouse):	Fstl3 (follistatin-like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Fstl3 (follistatin like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Fstl3 (follistatin like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FSTL3 (follistatin like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FSTL3 (follistatin like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Fstl3 (follistatin like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FSTL3 (follistatin like 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LOC103233581 (follistatin-related protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,843,906 - 7,848,134 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	7,842,903 - 7,848,181 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebral creatine deficiency syndrome (ISO)

cyclic hematopoiesis (ISO)

genetic disease (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adrenal gland development (ISO)

cellular response to metal ion (ISO)

hematopoietic progenitor cell differentiation (ISO)

kidney development (ISO)

lung development (ISO)

male gonad development (ISO)

negative regulation of activin receptor signaling pathway (ISO)

negative regulation of BMP signaling pathway (ISO)

negative regulation of osteoclast differentiation (ISO)

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (ISO)

positive regulation of cell-cell adhesion (ISO)

positive regulation of transcription by RNA polymerase II (ISO)

regulation of transcription by RNA polymerase II (ISO)

spermatogenesis (ISO)

Cellular Component

extracellular space (ISO)

neuron projection terminus (ISO)

nucleoplasm (ISO)

nucleus (ISO)

secretory granule (ISO)

Molecular Function

activin binding (ISO)

fibronectin binding (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Fstl3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	7,843,906 - 7,848,134 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	7,842,903 - 7,848,181 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

FSTL3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	676,392 - 683,385 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	676,392 - 683,392 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	676,392 - 683,385 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	627,389 - 634,392 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	627,416 - 634,389	NCBI
Celera	19	134,214 - 141,222 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	446,191 - 453,199 (+)	NCBI		HuRef
CHM1_1	19	676,089 - 683,092 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	630,475 - 637,473 (+)	NCBI		T2T-CHM13v2.0

Fstl3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	79,613,108 - 79,618,464 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	79,613,106 - 79,618,464 (+)	Ensembl		GRCm39 Ensembl
GRCm38	10	79,777,274 - 79,782,630 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	79,777,272 - 79,782,630 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	79,240,019 - 79,245,375 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,180,424 - 79,185,451 (+)	NCBI		MGSCv36	mm8
Celera	10	80,791,969 - 80,797,325 (+)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

Fstl3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	10,574,195 - 10,579,844 (-)	NCBI		GRCr8
mRatBN7.2	7	9,923,574 - 9,929,223 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,923,576 - 9,939,639 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,805,686 - 12,810,209 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	14,683,767 - 14,688,290 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	12,543,082 - 12,547,606 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,806,031 - 12,810,556 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,804,919 - 12,810,570 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,976,235 - 12,980,760 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	11,438,360 - 11,442,885 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	11,437,263 - 11,442,906 (-)	NCBI
Celera	7	8,098,196 - 8,102,721 (-)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Fstl3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955495	7,078,427 - 7,082,717 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955495	7,077,424 - 7,082,768 (-)	NCBI	ChiLan1.0	ChiLan1.0

FSTL3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	5,001,470 - 5,008,587 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	4,239,588 - 4,246,692 (+)	NCBI		NHGRI_mPanPan1

FSTL3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,878,623 - 57,884,240 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	57,879,722 - 57,884,172 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	57,680,806 - 57,686,436 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	58,621,365 - 58,627,006 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	58,621,362 - 58,626,955 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	57,675,541 - 57,681,139 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	58,155,035 - 58,160,630 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	58,358,373 - 58,363,941 (-)	NCBI		UU_Cfam_GSD_1.0

Fstl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	217,578,861 - 217,584,426 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936588	250,249 - 256,902 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936588	250,359 - 255,922 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FSTL3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	77,656,663 - 77,662,613 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	77,656,655 - 77,662,608 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

LOC103233581
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	425,050 - 435,931 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	425,106 - 436,431 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	8,513,455 - 8,530,949 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013065861	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021245074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01083454	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSHGLT00000026156 ⟹ ENSHGLP00000025927

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624828	7,843,906 - 7,848,134 (-)	Ensembl

RefSeq Acc Id:

XM_013065861 ⟹ XP_012921315

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624828	7,842,903 - 7,848,177 (-)	NCBI

RefSeq Acc Id:

XM_021245074 ⟹ XP_021100733

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624828	7,842,903 - 7,848,181 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_012921315	(Get FASTA)	NCBI Sequence Viewer
	XP_021100733	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSHGLP00000025927

RefSeq Acc Id:	XP_021100733 ⟸ XM_021245074
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_012921315 ⟸ XM_013065861
- Peptide Label:	isoform X2

RefSeq Acc Id:

ENSHGLP00000025927 ⟸ ENSHGLT00000026156

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000018452	Ensembl, ENTREZGENE
Ensembl Transcript	ENSHGLT00000026156	ENTREZGENE
NCBI Gene	Fstl3	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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