Tmco6 (transmembrane and coiled-coil domains 6) - Rat Genome Database

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Gene: Tmco6 (transmembrane and coiled-coil domains 6) Heterocephalus glaber
Analyze
Symbol: Tmco6
Name: transmembrane and coiled-coil domains 6
RGD ID: 18913916
Description: ENCODES a protein that exhibits nuclear import signal receptor activity (inferred); INVOLVED IN catabolic process (inferred); protein import into nucleus (inferred); protein transport (inferred); ASSOCIATED WITH autosomal dominant intellectual developmental disorder 31 (ortholog); familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); FOUND IN endosome (inferred); ESCRT I complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transmembrane and coiled-coil domain-containing protein 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,382,973 - 33,401,509 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,383,047 - 33,398,774 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Tmco6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,382,973 - 33,401,509 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,383,047 - 33,398,774 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TMCO6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,596,530 - 140,647,732 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,639,435 - 140,645,408 (+)EnsemblGRCh38hg38GRCh38
GRCh375140,019,036 - 140,024,989 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,999,196 - 140,005,173 (+)NCBINCBI36Build 36hg18NCBI36
Celera5136,095,757 - 136,101,734 (+)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5135,164,249 - 135,170,226 (+)NCBIHuRef
CHM1_15139,452,252 - 139,458,225 (+)NCBICHM1_1
T2T-CHM13v2.05141,121,974 - 141,172,663 (+)NCBIT2T-CHM13v2.0
Tmco6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,868,072 - 36,875,453 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,868,092 - 36,875,450 (+)EnsemblGRCm39 Ensembl
GRCm381836,735,019 - 36,742,400 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,735,039 - 36,742,397 (+)EnsemblGRCm38mm10GRCm38
MGSCv371836,894,724 - 36,902,045 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,861,042 - 36,868,371 (+)NCBIMGSCv36mm8
Celera1837,187,143 - 37,194,456 (+)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Tmco6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,623,269 - 28,629,864 (+)NCBIGRCr8
mRatBN7.21828,349,248 - 28,355,843 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,349,248 - 28,355,843 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,476,398 - 28,482,993 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01829,238,478 - 29,245,067 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,573,700 - 28,580,295 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,579,145 - 29,585,740 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,579,145 - 29,585,740 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01829,282,952 - 29,289,547 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,435,248 - 29,441,843 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,462,029 - 29,466,164 (+)NCBI
Celera1828,069,801 - 28,076,396 (+)NCBICelera
Cytogenetic Map18p11NCBI
Tmco6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541855,110 - 61,705 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541855,110 - 61,670 (-)NCBIChiLan1.0ChiLan1.0
TMCO6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,897,098 - 135,903,122 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15134,036,691 - 134,042,673 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05136,003,993 - 136,009,960 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15142,120,756 - 142,126,727 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5142,120,756 - 142,126,727 (+)Ensemblpanpan1.1panPan2
TMCO6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,797,298 - 35,803,491 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,797,464 - 35,803,199 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,836,310 - 32,842,502 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0236,252,697 - 36,259,144 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl236,252,863 - 36,258,852 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1233,305,443 - 33,311,513 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0234,173,074 - 34,179,277 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,925,782 - 34,931,978 (+)NCBIUU_Cfam_GSD_1.0
Tmco6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,024,429 - 152,032,212 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,579,316 - 9,587,009 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,579,316 - 9,587,057 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMCO6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,352,030 - 142,359,036 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,352,006 - 142,359,040 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22148,295,948 - 148,302,984 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMCO6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12343,272,568 - 43,278,525 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2343,272,662 - 43,278,223 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,605,998 - 34,611,962 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000011023   ⟹   ENSHGLP00000010901
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474333,382,973 - 33,401,509 (+)Ensembl
RefSeq Acc Id: XM_004841894   ⟹   XP_004841951
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,383,047 - 33,398,774 (+)NCBI
RefSeq Acc Id: XM_004841895   ⟹   XP_004841952
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,383,047 - 33,398,774 (+)NCBI
RefSeq Acc Id: XM_004841896   ⟹   XP_004841953
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,383,047 - 33,397,956 (+)NCBI
RefSeq Acc Id: XM_004841897   ⟹   XP_004841954
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474333,383,047 - 33,397,956 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004841951 (Get FASTA)   NCBI Sequence Viewer  
  XP_004841952 (Get FASTA)   NCBI Sequence Viewer  
  XP_004841953 (Get FASTA)   NCBI Sequence Viewer  
  XP_004841954 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000010901
GenBank Protein JAN97867 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004841951   ⟸   XM_004841894
- Peptide Label: isoform X1
- UniProtKB: G5AR58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841952   ⟸   XM_004841895
- Peptide Label: isoform X2
- UniProtKB: G5AR58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841953   ⟸   XM_004841896
- Peptide Label: isoform X3
- UniProtKB: G5AR58 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004841954   ⟸   XM_004841897
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J1A7 (UniProtKB/TrEMBL),   G5AR58 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000010901   ⟸   ENSHGLT00000011023


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007817 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011023 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  Armadillo UniProtKB/TrEMBL
  Importin-a_IBB UniProtKB/TrEMBL
  Mod_r UniProtKB/TrEMBL
NCBI Gene Tmco6 ENTREZGENE
PANTHER TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 UniProtKB/TrEMBL
  TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 UniProtKB/TrEMBL
PROSITE IBB UniProtKB/TrEMBL
  VPS37_C UniProtKB/TrEMBL
SMART ARM UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
UniProt A0A0P6J1A7 ENTREZGENE, UniProtKB/TrEMBL
  G5AR58 ENTREZGENE, UniProtKB/TrEMBL