Mcidas (multiciliate differentiation and DNA synthesis associated cell cycle protein) - Rat Genome Database

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Gene: Mcidas (multiciliate differentiation and DNA synthesis associated cell cycle protein) Heterocephalus glaber
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Symbol: Mcidas
Name: multiciliate differentiation and DNA synthesis associated cell cycle protein
RGD ID: 18913910
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN motile cilium assembly (ortholog); regulation of cilium assembly (ortholog); regulation of DNA-templated DNA replication initiation (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); primary ciliary dyskinesia (ortholog); FOUND IN nuclear body (ortholog); nucleolus (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: multicilin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,038,732 - 4,045,351 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,038,668 - 4,045,607 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nuclear body  (ISO)
nucleolus  (ISO)
nucleus  (IEA,ISO)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mcidas
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247594,038,732 - 4,045,351 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247594,038,668 - 4,045,607 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MCIDAS
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38555,219,564 - 55,227,315 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl555,219,564 - 55,227,315 (-)EnsemblGRCh38hg38GRCh38
GRCh37554,515,392 - 54,523,143 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36554,551,411 - 54,559,720 (-)NCBINCBI36Build 36hg18NCBI36
Celera551,468,215 - 51,475,934 (-)NCBICelera
Cytogenetic Map5q11.2NCBI
HuRef551,488,443 - 51,496,162 (-)NCBIHuRef
CHM1_1554,519,283 - 54,527,002 (-)NCBICHM1_1
T2T-CHM13v2.0556,046,854 - 56,054,605 (-)NCBIT2T-CHM13v2.0
Mcidas
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3913113,130,104 - 113,138,233 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl13113,130,379 - 113,136,928 (+)EnsemblGRCm39 Ensembl
GRCm3813112,993,581 - 113,000,394 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl13112,993,845 - 113,000,394 (+)EnsemblGRCm38mm10GRCm38
MGSCv3713113,784,076 - 113,790,602 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3613114,114,746 - 114,121,272 (+)NCBIMGSCv36mm8
Celera13117,311,043 - 117,317,582 (+)NCBICelera
Cytogenetic Map13D2.2NCBI
cM Map1363.93NCBI
Mcidas
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8246,370,017 - 46,377,747 (+)NCBIGRCr8
mRatBN7.2244,636,820 - 44,644,551 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl244,636,856 - 44,642,601 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.0244,863,246 - 44,869,732 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl244,863,252 - 44,870,536 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0263,902,057 - 63,908,469 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4244,384,186 - 44,390,539 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera240,410,207 - 40,417,348 (+)NCBICelera
Cytogenetic Map2q14NCBI
Mcidas
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544612,438,737 - 12,445,254 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544612,438,737 - 12,445,254 (+)NCBIChiLan1.0ChiLan1.0
MCIDAS
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2458,713,473 - 58,721,891 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1556,867,103 - 56,875,521 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0558,802,664 - 58,811,075 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1560,425,341 - 60,433,035 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl560,425,341 - 60,433,035 (+)Ensemblpanpan1.1panPan2
MCIDAS
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1242,577,028 - 42,583,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl242,577,039 - 42,583,011 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha239,620,953 - 39,628,779 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0243,038,903 - 43,046,722 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl243,040,133 - 43,046,722 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1240,117,516 - 40,125,325 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0240,919,280 - 40,927,087 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0241,742,233 - 41,750,038 (-)NCBIUU_Cfam_GSD_1.0
Mcidas
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213203,597,126 - 203,603,667 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648012,533,713 - 12,539,387 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648012,533,604 - 12,539,639 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCIDAS
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1634,376,959 - 34,384,453 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11634,377,130 - 34,386,095 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21636,422,904 - 36,425,070 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCIDAS
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1451,454,155 - 51,464,823 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl451,455,506 - 51,462,302 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666049322,285 - 331,786 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021261422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01039100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000005059   ⟹   ENSHGLP00000004994
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247594,038,732 - 4,045,351 (+)Ensembl
RefSeq Acc Id: XM_021261422   ⟹   XP_021117081
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247594,038,668 - 4,045,607 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021117081 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004994
RefSeq Acc Id: XP_021117081   ⟸   XM_021261422
- UniProtKB: G5C6X2 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000004994   ⟸   ENSHGLT00000005059


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003661 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005059 ENTREZGENE
Gene3D-CATH Geminin coiled-coil domain UniProtKB/TrEMBL
InterPro Geminin/Multicilin UniProtKB/TrEMBL
NCBI Gene Mcidas ENTREZGENE
PANTHER GEMININ UniProtKB/TrEMBL
  MULTICILIN UniProtKB/TrEMBL
Pfam Geminin UniProtKB/TrEMBL
Superfamily-SCOP Geminin coiled-coil domain UniProtKB/TrEMBL
UniProt G5C6X2 ENTREZGENE, UniProtKB/TrEMBL