Litaf (lipopolysaccharide induced TNF factor) - Rat Genome Database

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Gene: Litaf (lipopolysaccharide induced TNF factor) Heterocephalus glaber
Analyze
Symbol: Litaf
Name: lipopolysaccharide induced TNF factor
RGD ID: 18913775
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cellular response to lipopolysaccharide (ortholog); negative regulation of non-canonical NF-kappaB signal transduction (ortholog); positive regulation of canonical NF-kappaB signal transduction (ortholog); ASSOCIATED WITH Charcot-Marie-Tooth disease (ortholog); Charcot-Marie-Tooth disease type 1 (ortholog); Charcot-Marie-Tooth disease type 1C (ortholog); FOUND IN cytoplasmic side of early endosome membrane (ortholog); cytoplasmic side of plasma membrane (ortholog); intracellular membrane-bounded organelle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: lipopolysaccharide-induced tumor necrosis factor-alpha factor; lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog; Lipopolysaccharide-induced tumor necrosis factor-alpha factor-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247826,720,497 - 6,747,317 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247826,715,584 - 6,748,873 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Litaf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247826,720,497 - 6,747,317 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247826,715,584 - 6,748,873 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
LITAF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381611,547,722 - 11,640,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1611,547,722 - 11,636,381 (-)EnsemblGRCh38hg38GRCh38
GRCh371611,641,578 - 11,681,322 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361611,549,357 - 11,587,730 (-)NCBINCBI36Build 36hg18NCBI36
Build 341611,549,957 - 11,587,730NCBI
Celera1611,813,516 - 11,854,903 (-)NCBICelera
Cytogenetic Map16p13.13NCBI
HuRef1611,558,982 - 11,598,664 (-)NCBIHuRef
CHM1_11611,641,642 - 11,681,379 (-)NCBICHM1_1
T2T-CHM13v2.01611,583,827 - 11,676,644 (-)NCBIT2T-CHM13v2.0
Litaf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,777,137 - 10,810,985 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1610,777,139 - 10,884,021 (-)EnsemblGRCm39 Ensembl
GRCm381610,959,273 - 10,993,121 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,959,275 - 11,066,157 (-)EnsemblGRCm38mm10GRCm38
MGSCv371610,959,366 - 10,993,214 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361610,872,852 - 10,880,228 (-)NCBIMGSCv36mm8
Celera1611,588,622 - 11,622,564 (-)NCBICelera
Cytogenetic Map16A1NCBI
cM Map166.28NCBI
Litaf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8105,163,258 - 5,199,930 (+)NCBIGRCr8
mRatBN7.2104,656,308 - 4,692,981 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl104,625,552 - 4,692,763 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx109,352,930 - 9,389,597 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0108,874,034 - 8,910,699 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0104,512,289 - 4,548,952 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0104,753,546 - 4,763,272 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl104,719,713 - 4,763,510 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0103,580,243 - 3,589,969 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4104,614,177 - 4,623,903 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1104,587,486 - 4,623,903 (+)NCBI
Celera103,704,946 - 3,714,672 (+)NCBICelera
Cytogenetic Map10q11NCBI
Litaf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554427,077,823 - 7,083,437 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554427,054,418 - 7,084,973 (+)NCBIChiLan1.0ChiLan1.0
LITAF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21812,096,353 - 12,135,778 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11615,866,852 - 15,905,996 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01610,488,738 - 10,527,843 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11611,714,325 - 11,753,902 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1611,714,325 - 11,750,521 (-)Ensemblpanpan1.1panPan2
LITAF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,229,153 - 31,259,670 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha632,609,055 - 32,637,581 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0631,407,890 - 31,436,572 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl631,407,820 - 31,438,525 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1631,221,767 - 31,250,391 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0631,095,973 - 31,124,591 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0631,519,895 - 31,548,477 (+)NCBIUU_Cfam_GSD_1.0
Litaf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,563,943 - 111,567,545 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365309,409,692 - 9,421,974 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365309,409,378 - 9,421,974 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LITAF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl331,482,353 - 31,579,082 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1331,482,605 - 31,576,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2332,319,463 - 32,363,158 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LITAF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1511,023,158 - 11,099,133 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl511,021,717 - 11,059,149 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606819,054,852 - 19,135,028 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000018006   ⟹   ENSHGLP00000017829
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247826,720,497 - 6,747,317 (+)Ensembl
RefSeq Acc Id: XM_004855871   ⟹   XP_004855928
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247826,720,579 - 6,748,873 (+)NCBI
RefSeq Acc Id: XM_004855872   ⟹   XP_004855929
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247826,735,051 - 6,748,873 (+)NCBI
RefSeq Acc Id: XM_004855873   ⟹   XP_004855930
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247826,715,584 - 6,748,873 (+)NCBI
RefSeq Acc Id: XM_004855874   ⟹   XP_004855931
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247826,720,688 - 6,748,873 (+)NCBI
RefSeq Acc Id: XM_021237263   ⟹   XP_021092922
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247826,740,755 - 6,748,873 (+)NCBI
RefSeq Acc Id: XM_021237264   ⟹   XP_021092923
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247826,721,511 - 6,746,219 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004855930   ⟸   XM_004855873
- Peptide Label: isoform X2
- UniProtKB: G5B4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855928   ⟸   XM_004855871
- Peptide Label: isoform X2
- UniProtKB: G5B4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004855931   ⟸   XM_004855874
- Peptide Label: isoform X2
- UniProtKB: G5B4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092923   ⟸   XM_021237264
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004855929   ⟸   XM_004855872
- Peptide Label: isoform X2
- UniProtKB: G5B4G8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021092922   ⟸   XM_021237263
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ET20 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000017829   ⟸   ENSHGLT00000018006


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012766 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLG00100048322 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000018006 ENTREZGENE, UniProtKB/TrEMBL
  ENSHGLT00100071066 UniProtKB/TrEMBL
InterPro LITAF UniProtKB/TrEMBL
  LITAF_fam UniProtKB/TrEMBL
NCBI Gene Litaf ENTREZGENE
PANTHER LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR UniProtKB/TrEMBL
  PTHR23292 UniProtKB/TrEMBL
Pfam zf-LITAF-like UniProtKB/TrEMBL
PROSITE LITAF UniProtKB/TrEMBL
SMART LITAF UniProtKB/TrEMBL
UniProt A0A0N8ET20 ENTREZGENE, UniProtKB/TrEMBL
  G5B4G8 ENTREZGENE, UniProtKB/TrEMBL