Ogfod1 (2-oxoglutarate and iron dependent oxygenase domain containing 1) - Rat Genome Database

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Gene: Ogfod1 (2-oxoglutarate and iron dependent oxygenase domain containing 1) Heterocephalus glaber
Analyze
Symbol: Ogfod1
Name: 2-oxoglutarate and iron dependent oxygenase domain containing 1
RGD ID: 18913100
Description: ENCODES a protein that exhibits 2-oxoglutarate-dependent dioxygenase activity (inferred); dioxygenase activity (inferred); iron ion binding (inferred); INVOLVED IN cell population proliferation (inferred); regulation of translational termination (inferred); stress granule assembly (inferred); ASSOCIATED WITH Bardet-Biedl syndrome (ortholog); developmental and epileptic encephalopathy (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic stress granule (inferred); cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1; prolyl 3-hydroxylase OGFOD1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475791,854 - 115,133 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475792,670 - 116,127 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ogfod1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475791,854 - 115,133 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475792,670 - 116,127 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
OGFOD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381656,451,524 - 56,479,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1656,451,521 - 56,479,104 (+)EnsemblGRCh38hg38GRCh38
GRCh371656,485,436 - 56,513,016 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361655,042,925 - 55,068,908 (+)NCBINCBI36Build 36hg18NCBI36
Celera1640,983,443 - 41,009,426 (+)NCBICelera
Cytogenetic Map16q13NCBI
HuRef1642,355,849 - 42,381,832 (+)NCBIHuRef
CHM1_11657,892,420 - 57,918,407 (+)NCBICHM1_1
T2T-CHM13v2.01662,246,598 - 62,274,175 (+)NCBIT2T-CHM13v2.0
Ogfod1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39894,763,782 - 94,794,550 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl894,763,826 - 94,794,549 (+)EnsemblGRCm39 Ensembl
GRCm38894,037,122 - 94,067,922 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl894,037,198 - 94,067,921 (+)EnsemblGRCm38mm10GRCm38
MGSCv37896,561,098 - 96,591,822 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36896,926,420 - 96,957,051 (+)NCBIMGSCv36mm8
Celera898,368,451 - 98,399,175 (+)NCBICelera
Cytogenetic Map8C5NCBI
cM Map846.08NCBI
Ogfod1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81910,950,950 - 10,980,519 (-)NCBIGRCr8
mRatBN7.21910,945,031 - 10,974,602 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1910,946,018 - 10,975,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1910,918,802 - 10,942,463 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01911,683,973 - 11,707,634 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01910,970,978 - 10,994,643 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01911,425,301 - 11,451,085 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1911,425,105 - 11,451,278 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01911,399,734 - 11,425,518 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41911,382,885 - 11,412,512 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11911,391,459 - 11,417,244 (-)NCBI
Celera1910,833,456 - 10,859,240 (-)NCBICelera
Cytogenetic Map19p12NCBI
Ogfod1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543314,234,636 - 14,260,211 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543314,234,469 - 14,260,211 (+)NCBIChiLan1.0ChiLan1.0
OGFOD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21865,933,075 - 65,959,256 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11671,852,159 - 71,878,109 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01636,737,753 - 36,763,797 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11655,870,144 - 55,895,470 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1655,870,144 - 55,895,470 (+)Ensemblpanpan1.1panPan2
OGFOD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1259,711,440 - 59,736,448 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl259,711,890 - 59,736,216 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha256,345,122 - 56,370,151 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0260,256,515 - 60,281,555 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl260,255,426 - 60,281,048 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1257,086,854 - 57,111,887 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0258,095,694 - 58,120,747 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0258,988,675 - 59,013,708 (-)NCBIUU_Cfam_GSD_1.0
Ogfod1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934950,808,257 - 50,829,722 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364758,759,348 - 8,780,841 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364758,759,348 - 8,780,816 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OGFOD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl629,312,750 - 29,339,711 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1629,312,741 - 29,339,701 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OGFOD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1542,360,982 - 42,387,201 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl542,360,992 - 42,387,791 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604733,977,004 - 34,003,909 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019166   ⟹   ENSHGLP00000018977
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475791,854 - 115,133 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000019167   ⟹   ENSHGLP00000018978
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475794,810 - 114,996 (-)Ensembl
RefSeq Acc Id: XM_004847894   ⟹   XP_004847951
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475792,670 - 115,084 (-)NCBI
RefSeq Acc Id: XM_013073319   ⟹   XP_012928773
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475792,670 - 116,127 (-)NCBI
RefSeq Acc Id: XM_013073320   ⟹   XP_012928774
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475792,670 - 114,814 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004847951 (Get FASTA)   NCBI Sequence Viewer  
  XP_012928773 (Get FASTA)   NCBI Sequence Viewer  
  XP_012928774 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10579 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000018977
GenBank Protein JAN98019 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_012928773   ⟸   XM_013073319
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004847951   ⟸   XM_004847894
- Peptide Label: isoform X1
- UniProtKB: G5BMR8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012928774   ⟸   XM_013073320
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000018977   ⟸   ENSHGLT00000019166
RefSeq Acc Id: ENSHGLP00000018978   ⟸   ENSHGLT00000019167


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013601 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019166 ENTREZGENE
Gene3D-CATH q2cbj1_9rhob like domain UniProtKB/TrEMBL
InterPro Oxoglu/Fe-dep_dioxygenase UniProtKB/TrEMBL
  Oxoglutarate/Fe-dep_Oase_C UniProtKB/TrEMBL
  Pro_4_hyd_alph UniProtKB/TrEMBL
  TPA1/OFD1_N UniProtKB/TrEMBL
KEGG Report hgl:101721349 UniProtKB/TrEMBL
NCBI Gene Ogfod1 ENTREZGENE
PANTHER HISTONE ACETYLTRANSFERASE COMPLEX UniProtKB/TrEMBL
  PROLYL 3-HYDROXYLASE OGFOD1 UniProtKB/TrEMBL
Pfam 2OG-FeII_Oxy_4 UniProtKB/TrEMBL
  Ofd1_CTDD UniProtKB/TrEMBL
PROSITE FE2OG_OXY UniProtKB/TrEMBL
SMART P4Hc UniProtKB/TrEMBL
UniProt G5BMR8 ENTREZGENE, UniProtKB/TrEMBL