Tox2 (TOX high mobility group box family member 2) - Rat Genome Database

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Gene: Tox2 (TOX high mobility group box family member 2) Heterocephalus glaber
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Symbol: Tox2
Name: TOX high mobility group box family member 2
RGD ID: 18912865
Description: ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); transcription coactivator activity (ortholog); INVOLVED IN female gonad development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to gonadotropin (ortholog); ASSOCIATED WITH adenosine deaminase deficiency (ortholog); focal epilepsy (ortholog); T-Cell Immunodeficiency, Recurrent Infections, and Autoimmunity with or without Cardiac Malformations (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479010,339,858 - 10,467,837 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479010,339,928 - 10,467,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Tox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479010,339,858 - 10,467,837 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479010,339,928 - 10,467,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382043,914,852 - 44,069,616 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2043,914,852 - 44,069,616 (+)EnsemblGRCh38hg38GRCh38
GRCh372042,543,492 - 42,698,256 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362041,976,906 - 42,131,670 (+)NCBINCBI36Build 36hg18NCBI36
Build 342041,978,220 - 42,131,666NCBI
Celera2039,250,919 - 39,406,866 (+)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2039,278,939 - 39,434,941 (+)NCBIHuRef
CHM1_12042,447,111 - 42,601,501 (+)NCBICHM1_1
T2T-CHM13v2.02045,648,018 - 45,804,192 (+)NCBIT2T-CHM13v2.0
Tox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392163,045,047 - 163,166,092 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2163,045,045 - 163,166,090 (+)EnsemblGRCm39 Ensembl
GRCm382163,203,058 - 163,324,172 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2163,203,125 - 163,324,170 (+)EnsemblGRCm38mm10GRCm38
MGSCv372163,051,190 - 163,148,838 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362162,895,900 - 163,014,543 (+)NCBIMGSCv36mm8
Celera2169,172,013 - 169,272,833 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map284.14NCBI
Tox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83172,272,718 - 172,400,235 (+)NCBIGRCr8
mRatBN7.23151,853,294 - 151,980,086 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3151,853,294 - 151,980,749 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3155,660,818 - 155,787,503 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03164,159,772 - 164,286,456 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03161,903,840 - 162,030,363 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03159,569,329 - 159,694,756 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3159,569,363 - 159,694,756 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03165,761,081 - 165,890,364 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43154,075,542 - 154,205,141 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13153,981,577 - 154,111,177 (+)NCBI
Celera3150,510,051 - 150,636,666 (+)NCBICelera
Cytogenetic Map3q42NCBI
Tox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544513,208,413 - 13,314,827 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544513,210,606 - 13,343,344 (-)NCBIChiLan1.0ChiLan1.0
TOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22149,645,134 - 49,802,367 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12049,638,242 - 49,795,474 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02040,242,893 - 40,400,054 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12041,336,616 - 41,493,142 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2041,336,612 - 41,493,142 (+)Ensemblpanpan1.1panPan2
TOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12431,523,323 - 31,656,361 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2431,522,798 - 31,656,373 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2431,165,908 - 31,298,502 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02432,230,525 - 32,363,312 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2432,230,481 - 32,363,312 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12431,494,246 - 31,626,728 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02431,606,016 - 31,738,798 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02432,148,382 - 32,281,033 (+)NCBIUU_Cfam_GSD_1.0
Tox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640180,531,824 - 180,659,438 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365302,646,774 - 2,727,618 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365302,646,783 - 2,774,162 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1746,433,025 - 46,577,072 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11746,433,005 - 46,577,076 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21751,986,557 - 52,002,533 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1219,747,852 - 19,902,892 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl219,747,857 - 19,902,828 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605068,423,983 - 68,579,003 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000009250   ⟹   ENSHGLP00000009151
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479010,339,858 - 10,467,837 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000009251   ⟹   ENSHGLP00000009152
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479010,339,858 - 10,441,631 (-)Ensembl
RefSeq Acc Id: XM_004858201   ⟹   XP_004858258
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479010,339,928 - 10,441,261 (-)NCBI
RefSeq Acc Id: XM_004858202   ⟹   XP_004858259
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479010,339,928 - 10,467,855 (-)NCBI
RefSeq Acc Id: XM_013077102   ⟹   XP_012932556
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479010,339,928 - 10,441,229 (-)NCBI
RefSeq Acc Id: XM_013077103   ⟹   XP_012932557
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479010,339,928 - 10,467,252 (-)NCBI
RefSeq Acc Id: XM_013077104   ⟹   XP_012932558
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479010,339,928 - 10,466,784 (-)NCBI
RefSeq Acc Id: XM_021239065   ⟹   XP_021094724
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479010,339,928 - 10,441,504 (-)NCBI
RefSeq Acc Id: XP_004858259   ⟸   XM_004858202
- Peptide Label: isoform X3
- UniProtKB: G5BCW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932557   ⟸   XM_013077103
- Peptide Label: isoform X4
- UniProtKB: G5BCW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932558   ⟸   XM_013077104
- Peptide Label: isoform X4
- UniProtKB: G5BCW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094724   ⟸   XM_021239065
- Peptide Label: isoform X1
- UniProtKB: G5BCW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004858258   ⟸   XM_004858201
- Peptide Label: isoform X2
- UniProtKB: G5BCW6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012932556   ⟸   XM_013077102
- Peptide Label: isoform X4
- UniProtKB: G5BCW6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000009152   ⟸   ENSHGLT00000009251
Ensembl Acc Id: ENSHGLP00000009151   ⟸   ENSHGLT00000009250


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006575 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000009250 ENTREZGENE
  ENSHGLT00000009251 ENTREZGENE
Gene3D-CATH High mobility group box domain UniProtKB/TrEMBL
InterPro HMG_box_dom UniProtKB/TrEMBL
  HMG_box_dom_sf UniProtKB/TrEMBL
  TOX_HMG-box_domain UniProtKB/TrEMBL
NCBI Gene Tox2 ENTREZGENE
PANTHER AGAP000281-PA UniProtKB/TrEMBL
  TOX HIGH MOBILITY GROUP BOX FAMILY MEMBER 2 UniProtKB/TrEMBL
Pfam HMG_box UniProtKB/TrEMBL
PRINTS HIGHMOBLTY12 UniProtKB/TrEMBL
PROSITE HMG_BOX_2 UniProtKB/TrEMBL
SMART HMG UniProtKB/TrEMBL
Superfamily-SCOP HMG-box UniProtKB/TrEMBL
UniProt G5BCW6 ENTREZGENE, UniProtKB/TrEMBL