Espn (espin) - Rat Genome Database

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Gene: Espn (espin) Heterocephalus glaber
Analyze
Symbol: Espn
Name: espin
RGD ID: 18912717
Description: ENCODES a protein that exhibits actin filament binding (ortholog); SH3 domain binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); locomotory behavior (ortholog); microvillar actin bundle assembly (ortholog); PARTICIPATES IN auditory mechanotransduction pathway; ASSOCIATED WITH autosomal recessive nonsyndromic deafness (ortholog); autosomal recessive nonsyndromic deafness 36 (ortholog); chromosome 1p36 deletion syndrome (ortholog); FOUND IN actin cytoskeleton (ortholog); brush border (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,042,724 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248185,015,275 - 5,042,862 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Espn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,042,724 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248185,015,275 - 5,042,862 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ESPN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816,424,776 - 6,461,370 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16,424,776 - 6,461,367 (+)EnsemblGRCh38hg38GRCh38
GRCh3716,484,836 - 6,521,004 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616,407,435 - 6,443,591 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416,419,113 - 6,455,255NCBI
Celera15,599,359 - 5,635,452 (+)NCBICelera
Cytogenetic Map1p36.31NCBI
HuRef15,632,355 - 5,668,547 (+)NCBIHuRef
CHM1_116,473,408 - 6,509,542 (+)NCBICHM1_1
T2T-CHM13v2.015,950,417 - 5,987,012 (+)NCBIT2T-CHM13v2.0
Espn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394152,204,788 - 152,236,871 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4152,204,788 - 152,236,828 (-)EnsemblGRCm39 Ensembl
GRCm384152,120,331 - 152,152,414 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4152,120,331 - 152,152,371 (-)EnsemblGRCm38mm10GRCm38
MGSCv374151,494,985 - 151,526,316 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364150,964,677 - 150,996,007 (-)NCBIMGSCv36mm8
Celera4154,407,406 - 154,438,512 (-)NCBICelera
Cytogenetic Map4E2NCBI
cM Map482.9NCBI
Espn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85167,909,271 - 167,943,168 (-)NCBIGRCr8
mRatBN7.25162,626,560 - 162,660,439 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5162,626,560 - 162,660,256 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5165,329,492 - 165,363,610 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05167,151,038 - 167,185,203 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05167,113,244 - 167,147,401 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05169,293,356 - 169,331,338 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5169,293,904 - 169,331,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05172,851,807 - 172,885,845 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45169,349,723 - 169,382,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15169,359,914 - 169,392,264 (-)NCBI
Celera5160,858,704 - 160,892,256 (-)NCBICelera
Cytogenetic Map5q36NCBI
Espn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554866,130,190 - 6,156,859 (-)NCBIChiLan1.0ChiLan1.0
ESPN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21221,766,953 - 221,804,885 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11220,409,018 - 220,446,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v015,184,666 - 5,222,473 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.116,440,951 - 6,475,253 (+)NCBIpanpan1.1PanPan1.1panPan2
ESPN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1560,285,185 - 60,316,261 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl560,285,312 - 60,315,676 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha560,295,201 - 60,325,841 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0560,501,302 - 60,531,937 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl560,501,302 - 60,531,352 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1560,500,632 - 60,531,235 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0560,367,399 - 60,398,004 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0560,768,952 - 60,799,595 (+)NCBIUU_Cfam_GSD_1.0
Espn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505830,735,187 - 30,764,505 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366231,220,593 - 1,248,993 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366231,220,435 - 1,249,743 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ESPN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl667,284,079 - 67,316,591 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1667,284,106 - 67,316,577 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2662,236,643 - 62,268,608 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ESPN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120125,282,283 - 125,320,436 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20125,278,313 - 125,320,365 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605429,337,935 - 29,376,129 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000012242   ⟹   ENSHGLP00000012109
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,042,724 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000012243   ⟹   ENSHGLP00000012110
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,042,724 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000012244   ⟹   ENSHGLP00000012111
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,042,724 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000012245   ⟹   ENSHGLP00000012112
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,029,972 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000012246   ⟹   ENSHGLP00000012113
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,025,708 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000012247   ⟹   ENSHGLP00000012114
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248185,016,019 - 5,022,784 (-)Ensembl
RefSeq Acc Id: XM_004863716   ⟹   XP_004863773
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248185,015,275 - 5,042,862 (-)NCBI
RefSeq Acc Id: XM_004863717   ⟹   XP_004863774
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248185,015,275 - 5,042,860 (-)NCBI
RefSeq Acc Id: XM_013065050   ⟹   XP_012920504
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248185,015,275 - 5,031,429 (-)NCBI
RefSeq Acc Id: XM_021243377   ⟹   XP_021099036
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248185,015,275 - 5,042,860 (-)NCBI
RefSeq Acc Id: XM_021243378   ⟹   XP_021099037
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248185,015,275 - 5,031,429 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004863773   ⟸   XM_004863716
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021099036   ⟸   XM_021243377
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004863774   ⟸   XM_004863717
- Peptide Label: isoform X2
RefSeq Acc Id: XP_012920504   ⟸   XM_013065050
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021099037   ⟸   XM_021243378
- Peptide Label: isoform X4
RefSeq Acc Id: ENSHGLP00000012114   ⟸   ENSHGLT00000012247
RefSeq Acc Id: ENSHGLP00000012110   ⟸   ENSHGLT00000012243
RefSeq Acc Id: ENSHGLP00000012111   ⟸   ENSHGLT00000012244
RefSeq Acc Id: ENSHGLP00000012109   ⟸   ENSHGLT00000012242
RefSeq Acc Id: ENSHGLP00000012113   ⟸   ENSHGLT00000012246
RefSeq Acc Id: ENSHGLP00000012112   ⟸   ENSHGLT00000012245


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008665 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000012243 ENTREZGENE
  ENSHGLT00000012245 ENTREZGENE
NCBI Gene Espn ENTREZGENE