Sfmbt1 (Scm like with four mbt domains 1) - Rat Genome Database

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Gene: Sfmbt1 (Scm like with four mbt domains 1) Heterocephalus glaber
Analyze
Symbol: Sfmbt1
Name: Scm like with four mbt domains 1
RGD ID: 18912025
Description: ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); transcription corepressor activity (inferred); INVOLVED IN negative regulation of muscle organ development (ortholog); ASSOCIATED WITH congenital disorder of glycosylation In (ortholog); FOUND IN nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: scm-like with four MBT domains protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,160,661 - 4,328,058 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Sfmbt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248224,160,661 - 4,328,058 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SFMBT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38352,903,572 - 53,046,073 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl352,903,572 - 53,046,750 (-)EnsemblGRCh38hg38GRCh38
GRCh37352,937,588 - 53,080,089 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36352,913,667 - 53,055,110 (-)NCBINCBI36Build 36hg18NCBI36
Build 34352,913,667 - 53,055,110NCBI
Celera352,916,400 - 53,047,177 (-)NCBICelera
Cytogenetic Map3p21.1NCBI
HuRef352,999,200 - 53,129,628 (-)NCBIHuRef
CHM1_1352,889,772 - 53,031,734 (-)NCBICHM1_1
T2T-CHM13v2.0352,936,457 - 53,078,977 (-)NCBIT2T-CHM13v2.0
Sfmbt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391430,436,806 - 30,544,678 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1430,436,806 - 30,544,678 (+)EnsemblGRCm39 Ensembl
GRCm381430,714,849 - 30,822,721 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1430,714,849 - 30,822,721 (+)EnsemblGRCm38mm10GRCm38
MGSCv371431,528,035 - 31,635,907 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361429,595,009 - 29,646,972 (+)NCBIMGSCv36mm8
Celera1426,972,255 - 27,079,725 (+)NCBICelera
Cytogenetic Map14BNCBI
cM Map1418.99NCBI
Sfmbt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8165,896,686 - 6,016,311 (+)NCBIGRCr8
mRatBN7.2165,889,046 - 6,009,860 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl165,890,782 - 6,006,605 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx165,903,220 - 6,017,256 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0167,048,672 - 7,162,718 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0165,901,842 - 6,023,496 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0166,775,648 - 6,896,155 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl166,779,281 - 6,895,299 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0166,705,856 - 6,825,699 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4166,124,155 - 6,241,008 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1166,185,489 - 6,241,002 (+)NCBI
Celera169,184,923 - 9,236,952 (-)NCBICelera
Cytogenetic Map16p16NCBI
Sfmbt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554302,856,054 - 2,915,517 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554302,850,149 - 3,014,859 (-)NCBIChiLan1.0ChiLan1.0
SFMBT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2252,899,440 - 53,045,144 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1352,904,212 - 53,049,915 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0352,841,693 - 52,991,613 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1354,071,144 - 54,215,061 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl354,071,144 - 54,138,538 (-)Ensemblpanpan1.1panPan2
SFMBT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12036,853,108 - 36,978,306 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2036,921,566 - 36,972,675 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2036,788,231 - 36,914,516 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02037,130,153 - 37,256,719 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2037,183,169 - 37,251,023 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12036,567,757 - 36,687,554 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02036,928,798 - 37,055,250 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02037,207,224 - 37,327,384 (+)NCBIUU_Cfam_GSD_1.0
Sfmbt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118170,511,523 - 170,644,846 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364733,654,555 - 3,781,577 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364733,650,096 - 3,784,191 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SFMBT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1335,025,769 - 35,180,042 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11335,020,627 - 35,181,074 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21338,213,183 - 38,314,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SFMBT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12214,285,362 - 14,439,624 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2214,290,494 - 14,438,192 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041152,456,991 - 152,611,732 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021244049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021244057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002389216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01081153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01081165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_021244049   ⟹   XP_021099708
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,186,122 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244050   ⟹   XP_021099709
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,160,661 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244051   ⟹   XP_021099710
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,186,122 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244052   ⟹   XP_021099711
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,160,661 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244053   ⟹   XP_021099712
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,186,122 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244054   ⟹   XP_021099713
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,273,861 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244055   ⟹   XP_021099714
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,186,119 - 4,319,874 (+)NCBI
RefSeq Acc Id: XM_021244056   ⟹   XP_021099715
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,217,863 - 4,322,266 (+)NCBI
RefSeq Acc Id: XM_021244057   ⟹   XP_021099716
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,186,115 - 4,314,872 (+)NCBI
RefSeq Acc Id: XR_002389216
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248224,186,122 - 4,328,058 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021099709   ⟸   XM_021244050
- Peptide Label: isoform X1
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099711   ⟸   XM_021244052
- Peptide Label: isoform X1
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099716   ⟸   XM_021244057
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021099714   ⟸   XM_021244055
- Peptide Label: isoform X4
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099708   ⟸   XM_021244049
- Peptide Label: isoform X1
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099712   ⟸   XM_021244053
- Peptide Label: isoform X2
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099710   ⟸   XM_021244051
- Peptide Label: isoform X1
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099715   ⟸   XM_021244056
- Peptide Label: isoform X1
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021099713   ⟸   XM_021244054
- Peptide Label: isoform X3
- UniProtKB: G5BUN6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009343 ENTREZGENE
Ensembl Transcript ENSHGLT00000013207 ENTREZGENE
Gene3D-CATH 2.30.30.140 UniProtKB/TrEMBL
  SLED domain UniProtKB/TrEMBL
  Transcription Factor, Ets-1 UniProtKB/TrEMBL
InterPro Mbt UniProtKB/TrEMBL
  MBT_SFMBT1_rpt2 UniProtKB/TrEMBL
  MBT_SFMBT1_rpt3 UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Scm-like-4MBT1/2_SAM UniProtKB/TrEMBL
  SLED UniProtKB/TrEMBL
  SLED_sf UniProtKB/TrEMBL
NCBI Gene Sfmbt1 ENTREZGENE
PANTHER POLYCOMB GROUP PROTEIN UniProtKB/TrEMBL
  SCM-LIKE WITH FOUR MBT DOMAINS PROTEIN 1 UniProtKB/TrEMBL
Pfam MBT UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
  SLED UniProtKB/TrEMBL
PROSITE MBT UniProtKB/TrEMBL
SMART MBT UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
Superfamily-SCOP SAM/Pointed domain UniProtKB/TrEMBL
  Tudor/PWWP/MBT UniProtKB/TrEMBL
UniProt G5BUN6 ENTREZGENE, UniProtKB/TrEMBL