Ptprt (protein tyrosine phosphatase receptor type T) - Rat Genome Database

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Gene: Ptprt (protein tyrosine phosphatase receptor type T) Heterocephalus glaber
Analyze
Symbol: Ptprt
Name: protein tyrosine phosphatase receptor type T
RGD ID: 18911622
Description: ENCODES a protein that exhibits alpha-actinin binding (ortholog); alpha-catenin binding (ortholog); beta-catenin binding (ortholog); INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (ortholog); cellular response to interleukin-6 (ortholog); homophilic cell adhesion via plasma membrane adhesion molecules (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); colon cancer (ortholog); FOUND IN cell surface (ortholog); glutamatergic synapse (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: receptor-type tyrosine-protein phosphatase T
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479011,062,926 - 12,136,937 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Ptprt
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479011,062,926 - 12,136,937 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTPRT
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382042,031,890 - 43,189,906 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2042,072,752 - 43,189,970 (-)EnsemblGRCh38hg38GRCh38
GRCh372040,701,396 - 41,818,546 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362040,134,806 - 41,251,971 (-)NCBINCBI36Build 36hg18NCBI36
Build 342040,134,806 - 41,251,971NCBI
Celera2037,412,018 - 38,527,269 (-)NCBICelera
Cytogenetic Map20q12-q13.11NCBI
HuRef2037,438,892 - 38,251,263 (-)NCBIHuRef
CHM1_12040,605,787 - 41,722,632 (-)NCBICHM1_1
T2T-CHM13v2.02043,763,752 - 44,923,941 (-)NCBIT2T-CHM13v2.0
Ptprt
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392161,363,908 - 162,503,106 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2161,363,910 - 162,503,067 (-)EnsemblGRCm39 Ensembl
GRCm382161,521,988 - 162,661,147 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2161,521,990 - 162,661,147 (-)EnsemblGRCm38mm10GRCm38
MGSCv372161,353,359 - 162,486,883 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362161,219,064 - 162,352,588 (-)NCBIMGSCv36mm8
Celera2167,464,067 - 168,594,641 (-)NCBICelera
Cytogenetic Map2H2NCBI
cM Map281.91NCBI
Ptprt
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83170,608,993 - 171,707,692 (-)NCBIGRCr8
mRatBN7.23150,189,343 - 151,288,145 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3150,194,859 - 151,288,124 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3154,002,029 - 155,097,905 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03162,501,480 - 163,596,833 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03160,241,501 - 161,340,196 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03157,537,192 - 158,328,984 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3157,544,583 - 158,328,881 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03163,757,891 - 164,563,677 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43152,380,772 - 153,172,076 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13152,154,289 - 153,093,067 (-)NCBI
Celera3148,867,063 - 149,656,746 (-)NCBICelera
Cytogenetic Map3q42NCBI
Ptprt
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544514,185,732 - 14,952,980 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544514,185,751 - 14,961,000 (+)NCBIChiLan1.0ChiLan1.0
PTPRT
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22147,800,918 - 48,928,561 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12047,794,017 - 48,921,662 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02038,399,267 - 39,526,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12039,494,674 - 40,317,701 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2039,502,794 - 40,317,701 (-)Ensemblpanpan1.1panPan2
PTPRT
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12429,992,957 - 30,764,469 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2430,000,637 - 30,820,835 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2429,632,448 - 30,668,607 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02430,697,308 - 31,823,739 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2430,697,341 - 31,730,741 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12429,966,056 - 30,996,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02430,064,525 - 31,108,057 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02430,613,756 - 31,646,408 (-)NCBIUU_Cfam_GSD_1.0
Ptprt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640178,978,646 - 179,802,109 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365303,555,103 - 4,319,704 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365303,555,070 - 4,327,558 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPRT
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1744,714,645 - 45,881,041 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11744,717,539 - 45,880,822 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21749,805,722 - 49,866,203 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPRT
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1220,613,352 - 21,720,417 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605069,391,453 - 70,534,508 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000016821   ⟹   ENSHGLP00000016650
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479011,062,926 - 12,136,937 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000016822   ⟹   ENSHGLP00000016651
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479011,062,926 - 12,136,937 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000016823   ⟹   ENSHGLP00000016652
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479011,062,926 - 12,136,937 (+)Ensembl
RefSeq Acc Id: XM_021239029   ⟹   XP_021094688
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBI
RefSeq Acc Id: XM_021239030   ⟹   XP_021094689
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBI
RefSeq Acc Id: XM_021239031   ⟹   XP_021094690
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBI
RefSeq Acc Id: XM_021239032   ⟹   XP_021094691
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBI
RefSeq Acc Id: XM_021239033   ⟹   XP_021094692
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479011,368,745 - 12,144,895 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021094688 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094689 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094690 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094691 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094692 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000016650
Reference Protein Sequences
RefSeq Acc Id: XP_021094691   ⟸   XM_021239032
- Peptide Label: isoform X4
- UniProtKB: G5BCX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094692   ⟸   XM_021239033
- Peptide Label: isoform X5
- UniProtKB: G5BCX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094688   ⟸   XM_021239029
- Peptide Label: isoform X1
- UniProtKB: G5BCX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094689   ⟸   XM_021239030
- Peptide Label: isoform X2
- UniProtKB: G5BCX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021094690   ⟸   XM_021239031
- Peptide Label: isoform X3
- UniProtKB: G5BCX1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000016650   ⟸   ENSHGLT00000016821
RefSeq Acc Id: ENSHGLP00000016652   ⟸   ENSHGLT00000016823
RefSeq Acc Id: ENSHGLP00000016651   ⟸   ENSHGLT00000016822


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011912 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000016821 ENTREZGENE
Gene3D-CATH 2.60.120.200 UniProtKB/TrEMBL
  Immunoglobulins UniProtKB/TrEMBL
  Protein tyrosine phosphatase superfamily UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  MAM_dom UniProtKB/TrEMBL
  Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptprt ENTREZGENE
PANTHER PROTEIN-TYROSINE-PHOSPHATASE UniProtKB/TrEMBL
  SUSHI DOMAIN-CONTAINING PROTEIN 1 UniProtKB/TrEMBL
Pfam fn3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  Y_phosphatase UniProtKB/TrEMBL
PRINTS MAMDOMAIN UniProtKB/TrEMBL
  PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  MAM_1 UniProtKB/TrEMBL
  MAM_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  MAM UniProtKB/TrEMBL
  PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP (Phosphotyrosine protein) phosphatases II UniProtKB/TrEMBL
  Concanavalin A-like lectins/glucanases UniProtKB/TrEMBL
  Fibronectin type III UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
UniProt G5BCX1 ENTREZGENE, UniProtKB/TrEMBL