Pdia5 (protein disulfide isomerase family A member 5) - Rat Genome Database

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Gene: Pdia5 (protein disulfide isomerase family A member 5) Heterocephalus glaber
Analyze
Symbol: Pdia5
Name: protein disulfide isomerase family A member 5
RGD ID: 18911415
Description: ENCODES a protein that exhibits protein-disulfide reductase activity (ortholog); INVOLVED IN protein folding (inferred); ASSOCIATED WITH alkaptonuria (ortholog); COVID-19 (ortholog); familial hypocalciuric hypercalcemia (ortholog); FOUND IN endoplasmic reticulum (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: protein disulfide-isomerase A5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pdia5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PDIA5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383123,067,025 - 123,162,104 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3123,067,025 - 123,225,227 (+)EnsemblGRCh38hg38GRCh38
GRCh373122,785,872 - 122,880,951 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363124,268,655 - 124,363,567 (+)NCBINCBI36Build 36hg18NCBI36
Celera3121,192,646 - 121,287,739 (+)NCBICelera
Cytogenetic Map3q21.1NCBI
HuRef3120,158,749 - 120,254,205 (+)NCBIHuRef
CHM1_13122,749,529 - 122,844,663 (+)NCBICHM1_1
T2T-CHM13v2.03125,787,101 - 125,882,179 (+)NCBIT2T-CHM13v2.0
Pdia5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391635,217,678 - 35,311,289 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1635,217,682 - 35,311,243 (-)EnsemblGRCm39 Ensembl
GRCm381635,397,308 - 35,490,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,397,312 - 35,490,873 (-)EnsemblGRCm38mm10GRCm38
MGSCv371635,397,398 - 35,490,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,317,059 - 35,410,620 (-)NCBIMGSCv36mm8
Celera1635,866,403 - 35,959,222 (-)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1625.37NCBI
Pdia5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,777,436 - 78,892,370 (+)NCBIGRCr8
mRatBN7.21165,272,152 - 65,359,087 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1165,272,155 - 65,359,084 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1174,095,261 - 74,182,045 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,757,523 - 66,844,318 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,788,798 - 65,875,595 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,493,035 - 68,578,999 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,493,035 - 68,578,995 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,580,311 - 71,666,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,117,749 - 67,204,482 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11167,175,337 - 67,262,069 (+)NCBI
Celera1164,733,302 - 64,819,377 (+)NCBICelera
Cytogenetic Map11q22NCBI
Pdia5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542722,268,511 - 22,356,181 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542722,268,730 - 22,356,123 (+)NCBIChiLan1.0ChiLan1.0
PDIA5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,012,763 - 121,107,773 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,017,569 - 121,112,548 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03120,155,981 - 120,250,961 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13127,059,751 - 127,154,451 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3127,059,751 - 127,154,451 (+)Ensemblpanpan1.1panPan2
PDIA5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13326,131,969 - 26,227,256 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3326,131,893 - 26,227,253 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3326,154,925 - 26,249,690 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03326,365,077 - 26,460,503 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3326,364,927 - 26,460,501 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13326,161,419 - 26,256,156 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03326,204,706 - 26,300,729 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,763,803 - 26,858,825 (+)NCBIUU_Cfam_GSD_1.0
Pdia5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602128,116,195 - 128,206,073 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367252,024,643 - 2,114,560 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367252,024,646 - 2,114,530 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDIA5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13137,296,883 - 137,398,628 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113137,300,086 - 137,398,465 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213146,843,483 - 146,941,924 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDIA5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12257,711,049 - 57,806,058 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2257,711,041 - 57,806,037 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041108,540,265 - 108,633,350 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004873616   ⟹   XP_004873673
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBI
RefSeq Acc Id: XM_004873617   ⟹   XP_004873674
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249121,408,645 - 1,495,317 (+)NCBI
RefSeq Acc Id: XM_021251262   ⟹   XP_021106921
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBI
RefSeq Acc Id: XR_002391830
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBI
RefSeq Acc Id: XR_002391831
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249121,408,645 - 1,523,498 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004873673 (Get FASTA)   NCBI Sequence Viewer  
  XP_004873674 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106921 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003049
GenBank Protein JAN98503 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021106921   ⟸   XM_021251262
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J4Q6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004873673   ⟸   XM_004873616
- Peptide Label: isoform X1
- UniProtKB: A0A0P6J4Q6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004873674   ⟸   XM_004873617
- Peptide Label: isoform X3
- UniProtKB: A0A0P6J4Q6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002278 ENTREZGENE
Ensembl Transcript ENSHGLT00000003104 ENTREZGENE
Gene3D-CATH Glutaredoxin UniProtKB/TrEMBL
InterPro PDI_a_PDIR UniProtKB/TrEMBL
  PDIA5_N_PDI_b UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/TrEMBL
  Thioredoxin_CS UniProtKB/TrEMBL
  Thioredoxin_domain UniProtKB/TrEMBL
NCBI Gene Pdia5 ENTREZGENE
PANTHER PROTEIN DISULFIDE-ISOMERASE A5 UniProtKB/TrEMBL
  PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED UniProtKB/TrEMBL
Pfam Thioredoxin UniProtKB/TrEMBL
PRINTS THIOREDOXIN UniProtKB/TrEMBL
PROSITE THIOREDOXIN_1 UniProtKB/TrEMBL
  THIOREDOXIN_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF52833 UniProtKB/TrEMBL
UniProt A0A0P6J4Q6 ENTREZGENE, UniProtKB/TrEMBL