Ranbp1 (RAN binding protein 1) - Rat Genome Database

Name: Ranbp1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Ranbp1 (RAN binding protein 1) Heterocephalus glaber

Analyze

Symbol:

Ranbp1

Name:

RAN binding protein 1

RGD ID:

18910937

Description:

ENCODES a protein that exhibits GDP-dissociation inhibitor activity (ortholog); INVOLVED IN cellular response to leptomycin B (ortholog); cellular response to xenobiotic stimulus (ortholog); positive regulation of mitotic centrosome separation (ortholog); PARTICIPATES IN CRM1 export pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); autistic disorder (ortholog); chromosome 22q11.2 deletion syndrome, distal (ortholog); FOUND IN axon cytoplasm (ortholog); plasma membrane bounded cell projection cytoplasm (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

ran-specific GTPase-activating protein

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	RANBP1 (RAN binding protein 1)	NCBI	Ortholog
Mus musculus (house mouse):	Ranbp1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Ranbp1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ranbp1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	RANBP1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	RANBP1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	RANBP1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	RANBP1 (RAN binding protein 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	728,014 - 736,043 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	728,123 - 736,045 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

autistic disorder (ISO)

chromosome 22q11.2 deletion syndrome, distal (ISO)

chromosome 22q11.2 microduplication syndrome (ISO)

DiGeorge syndrome (ISO)

dilated cardiomyopathy (ISO)

epilepsy (ISO)

genetic disease (ISO)

hemorrhagic disease (ISO)

human immunodeficiency virus infectious disease (ISO)

intellectual disability (ISO)

Kidney Neoplasms (ISO)

megacolon (ISO)

myocardial infarction (ISO)

Neurodevelopmental Disorders (ISO)

primary immunodeficiency disease (ISO)

schizophrenia (ISO)

sciatic neuropathy (ISO)

velocardiofacial syndrome (ISO)

Venous Thrombosis (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to leptomycin B (ISO)

cellular response to xenobiotic stimulus (ISO)

NLS-bearing protein import into nucleus (IEA)

nucleocytoplasmic transport (IEA)

positive regulation of mitotic centrosome separation (IEA,ISO)

positive regulation of neuron projection development (ISO)

response to calcium ion (ISO)

spindle organization (IEA,ISO)

Cellular Component

axon cytoplasm (ISO)

centrosome (IEA)

cytoplasm (IEA)

cytosol (IEA)

nuclear pore (IEA)

plasma membrane bounded cell projection cytoplasm (ISO)

Molecular Function

GDP-dissociation inhibitor activity (ISO)

GTPase activator activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

CRM1 export pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Ranbp1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624747	728,014 - 736,043 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624747	728,123 - 736,045 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

RANBP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	20,116,104 - 20,127,355 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	20,115,938 - 20,127,355 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	20,103,627 - 20,114,878 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	18,485,024 - 18,494,704 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	22	18,479,577 - 18,489,258	NCBI
Celera	22	3,957,074 - 3,966,754 (+)	NCBI		Celera
Cytogenetic Map	22	q11.21	NCBI
HuRef	22	3,724,122 - 3,735,532 (+)	NCBI		HuRef
CHM1_1	22	20,103,145 - 20,114,571 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	20,495,154 - 20,506,390 (+)	NCBI		T2T-CHM13v2.0

Ranbp1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	18,057,843 - 18,066,558 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	18,057,648 - 18,066,596 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	18,239,979 - 18,248,694 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	18,239,784 - 18,248,732 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	18,240,072 - 18,248,787 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	18,153,377 - 18,162,265 (-)	NCBI		MGSCv36	mm8
Celera	16	18,812,725 - 18,821,440 (-)	NCBI		Celera
Cytogenetic Map	16	A3	NCBI
cM Map	16	11.3	NCBI

Ranbp1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	96,246,912 - 96,255,145 (+)	NCBI		GRCr8
mRatBN7.2	11	82,742,603 - 82,750,836 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	82,742,600 - 82,750,838 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	91,470,989 - 91,479,222 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	84,132,217 - 84,140,450 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	83,185,732 - 83,193,965 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	86,890,585 - 86,898,818 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	86,890,585 - 86,898,818 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	89,984,523 - 89,992,756 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	84,736,402 - 84,744,635 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	84,776,987 - 84,785,231 (+)	NCBI
Celera	11	81,519,608 - 81,527,841 (+)	NCBI		Celera
Cytogenetic Map	11	q23	NCBI

Ranbp1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955442	17,985,544 - 17,992,759 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955442	17,985,456 - 17,992,945 (-)	NCBI	ChiLan1.0	ChiLan1.0

RANBP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	29,744,646 - 29,754,878 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	32,291,533 - 32,301,752 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	2,877,954 - 2,888,035 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	18,550,699 - 18,560,875 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	18,549,055 - 18,560,573 (+)	Ensembl	panpan1.1		panPan2

RANBP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	26	29,211,559 - 29,219,247 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	26	29,211,863 - 29,220,451 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	26	29,170,472 - 29,178,153 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	26	30,615,598 - 30,623,280 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	26	30,615,149 - 30,624,491 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	26	28,663,443 - 28,671,126 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	26	28,288,807 - 28,296,490 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	26	29,373,800 - 29,381,482 (-)	NCBI		UU_Cfam_GSD_1.0

RANBP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	51,494,359 - 51,500,417 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	51,494,258 - 51,500,420 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	55,131,300 - 55,137,463 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

RANBP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	5,611,968 - 5,622,414 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	5,612,268 - 5,622,191 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666085	1,311,461 - 1,321,901 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_004843291	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_004843292	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_004843293	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021257096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021257097	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021257098	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AHKG01026483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GEBF01001872	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSHGLT00000009155 ⟹ ENSHGLP00000009058

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla_female_1.0 Ensembl	NW_004624747	728,014 - 736,043 (+)	Ensembl

RefSeq Acc Id:

XM_004843291 ⟹ XP_004843348

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624747	728,123 - 736,045 (+)	NCBI

RefSeq Acc Id:

XM_004843292 ⟹ XP_004843349

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624747	728,125 - 736,045 (+)	NCBI

RefSeq Acc Id:

XM_004843293 ⟹ XP_004843350

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624747	728,125 - 736,045 (+)	NCBI

RefSeq Acc Id:

XM_021257096 ⟹ XP_021112755

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624747	728,123 - 736,045 (+)	NCBI

RefSeq Acc Id:

XM_021257097 ⟹ XP_021112756

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624747	728,792 - 736,045 (+)	NCBI

RefSeq Acc Id:

XM_021257098 ⟹ XP_021112757

Type:

CODING

Position:

Naked Mole-Rat Assembly	Chr	Position (strand)	Source
HetGla 1.0	NW_004624747	730,101 - 736,045 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_004843348	(Get FASTA)	NCBI Sequence Viewer
	XP_004843349	(Get FASTA)	NCBI Sequence Viewer
	XP_004843350	(Get FASTA)	NCBI Sequence Viewer
	XP_021112755	(Get FASTA)	NCBI Sequence Viewer
	XP_021112756	(Get FASTA)	NCBI Sequence Viewer
	XP_021112757	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSHGLP00000009058
GenBank Protein	JAO01761	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	XP_004843348 ⟸ XM_004843291
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_021112755 ⟸ XM_021257096
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_004843349 ⟸ XM_004843292
- Peptide Label:	isoform X4
- UniProtKB:	G5CA28 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_004843350 ⟸ XM_004843293
- Peptide Label:	isoform X5
- UniProtKB:	A0A0P6JXD5 (UniProtKB/TrEMBL), G5CA28 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_021112756 ⟸ XM_021257097
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_021112757 ⟸ XM_021257098
- Peptide Label:	isoform X6

RefSeq Acc Id:

ENSHGLP00000009058 ⟸ ENSHGLT00000009155

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSHGLG00000006504	Ensembl, ENTREZGENE
Ensembl Transcript	ENSHGLT00000009155	ENTREZGENE
Gene3D-CATH	2.30.29.30	UniProtKB/TrEMBL
InterPro	PH-like_dom_sf	UniProtKB/TrEMBL
	Ran_bind_dom	UniProtKB/TrEMBL
	RanBP1-like	UniProtKB/TrEMBL
	RanBP1_RanBD	UniProtKB/TrEMBL
NCBI Gene	Ranbp1	ENTREZGENE
PANTHER	PTHR23138	UniProtKB/TrEMBL
	RANBD1 DOMAIN-CONTAINING PROTEIN	UniProtKB/TrEMBL
Pfam	Ran_BP1	UniProtKB/TrEMBL
PROSITE	RANBD1	UniProtKB/TrEMBL
SMART	RanBD	UniProtKB/TrEMBL
Superfamily-SCOP	PH domain-like	UniProtKB/TrEMBL
UniProt	A0A0P6JXD5	ENTREZGENE, UniProtKB/TrEMBL
	G5CA28	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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