Sema6b (semaphorin 6B) - Rat Genome Database

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Gene: Sema6b (semaphorin 6B) Heterocephalus glaber
Analyze
Symbol: Sema6b
Name: semaphorin 6B
RGD ID: 18910372
Description: ENCODES a protein that exhibits chemorepellent activity (inferred); semaphorin receptor binding (inferred); INVOLVED IN central nervous system development (ortholog); hippocampus development (ortholog); ASSOCIATED WITH amenorrhea (ortholog); autistic disorder (ortholog); cerebellar hypoplasia (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Semaphorin-6B
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,182,812 - 5,192,486 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,170,745 - 5,193,568 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Sema6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,182,812 - 5,192,486 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248285,170,745 - 5,193,568 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SEMA6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38194,542,593 - 4,559,684 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl194,542,593 - 4,581,776 (-)EnsemblGRCh38hg38GRCh38
GRCh37194,542,605 - 4,559,696 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36194,493,600 - 4,509,503 (-)NCBINCBI36Build 36hg18NCBI36
Build 34194,493,599 - 4,509,503NCBI
Celera194,481,386 - 4,497,296 (-)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef194,304,316 - 4,321,196 (-)NCBIHuRef
CHM1_1194,542,791 - 4,559,971 (-)NCBICHM1_1
T2T-CHM13v2.0194,526,261 - 4,543,368 (-)NCBIT2T-CHM13v2.0
Sema6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391756,430,085 - 56,447,343 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1756,430,085 - 56,447,343 (-)EnsemblGRCm39 Ensembl
GRCm381756,123,085 - 56,140,343 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1756,123,085 - 56,140,343 (-)EnsemblGRCm38mm10GRCm38
MGSCv371756,262,508 - 56,279,766 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361755,716,378 - 55,726,158 (-)NCBIMGSCv36mm8
Celera1759,541,746 - 59,547,130 (-)NCBICelera
Cytogenetic Map17DNCBI
cM Map1729.17NCBI
Sema6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr891,038,103 - 1,055,063 (-)NCBIGRCr8
mRatBN7.29950,939 - 967,905 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl9950,939 - 961,521 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx91,397,335 - 1,406,976 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.096,744,614 - 6,754,255 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.095,702,372 - 5,712,013 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0910,934,273 - 10,951,252 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl910,941,613 - 10,951,252 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.099,921,231 - 9,938,199 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,547,095 - 7,556,706 (+)NCBICelera
Cytogenetic Map9q11NCBI
Sema6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554954,388,516 - 4,399,313 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554954,387,147 - 4,399,430 (+)NCBIChiLan1.0ChiLan1.0
SEMA6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2208,937,116 - 8,975,577 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1198,166,915 - 8,205,350 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0193,562,673 - 3,600,981 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1194,510,286 - 4,528,178 (-)NCBIpanpan1.1PanPan1.1panPan2
SEMA6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,151,913 - 55,173,434 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,161,818 - 55,173,135 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2054,874,562 - 54,901,970 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02055,803,993 - 55,831,315 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2055,820,883 - 55,831,921 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12054,881,306 - 54,893,886 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02055,346,572 - 55,374,433 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02055,545,006 - 55,572,679 (+)NCBIUU_Cfam_GSD_1.0
Sema6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,172,541 - 215,192,053 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365882,642,859 - 2,653,742 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365882,642,730 - 2,654,520 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEMA6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl274,258,439 - 74,296,385 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1274,262,303 - 74,296,386 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SEMA6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.164,276,548 - 4,304,738 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660813,880,980 - 3,921,504 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000011381   ⟹   ENSHGLP00000011256
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248285,182,812 - 5,192,486 (+)Ensembl
RefSeq Acc Id: XM_013065962   ⟹   XP_012921416
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248285,170,745 - 5,193,568 (+)NCBI
Protein Sequences
Protein RefSeqs XP_012921416 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14607 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000011256
Reference Protein Sequences
RefSeq Acc Id: XP_012921416   ⟸   XM_013065962
- UniProtKB: G5BZ96 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000011256   ⟸   ENSHGLT00000011381


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000008078 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000011381 ENTREZGENE
Gene3D-CATH ligand-binding face of the semaphorins, domain 2 UniProtKB/TrEMBL
  YVTN repeat-like/Quinoprotein amine dehydrogenase UniProtKB/TrEMBL
InterPro Plexin_repeat UniProtKB/TrEMBL
  Semap_dom UniProtKB/TrEMBL
  Semap_dom_sf UniProtKB/TrEMBL
  Semaphorin UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
NCBI Gene Sema6b ENTREZGENE
PANTHER SEMAPHORIN UniProtKB/TrEMBL
  SEMAPHORIN-6B UniProtKB/TrEMBL
Pfam PSI UniProtKB/TrEMBL
  Sema UniProtKB/TrEMBL
PROSITE SEMA UniProtKB/TrEMBL
SMART Sema UniProtKB/TrEMBL
Superfamily-SCOP Plexin repeat UniProtKB/TrEMBL
  Sema domain UniProtKB/TrEMBL
UniProt G5BZ96 ENTREZGENE, UniProtKB/TrEMBL