Prpf6 (pre-mRNA processing factor 6) - Rat Genome Database

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Gene: Prpf6 (pre-mRNA processing factor 6) Heterocephalus glaber
Analyze
Symbol: Prpf6
Name: pre-mRNA processing factor 6
RGD ID: 18910343
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein-macromolecule adaptor activity (ortholog); ribonucleoprotein complex binding (ortholog); INVOLVED IN positive regulation of transcription by RNA polymerase II (ortholog); RNA localization (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH developmental and epileptic encephalopathy (ortholog); developmental and epileptic encephalopathy 33 (ortholog); early infantile epileptic encephalopathy (ortholog); FOUND IN nuclear speck (ortholog); nucleus (ortholog); U2-type precatalytic spliceosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: pre-mRNA-processing factor 6
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,601,047 - 29,664,054 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474129,601,050 - 29,664,054 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Prpf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474129,601,047 - 29,664,054 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474129,601,050 - 29,664,054 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRPF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382063,981,132 - 64,033,100 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2063,981,132 - 64,033,100 (+)EnsemblGRCh38hg38GRCh38
GRCh372062,612,485 - 62,664,453 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362062,082,875 - 62,134,897 (+)NCBINCBI36Build 36hg18NCBI36
Build 342062,082,900 - 62,134,895NCBI
Celera2059,299,064 - 59,350,558 (+)NCBICelera
Cytogenetic Map20q13.33NCBI
HuRef2059,347,184 - 59,398,551 (+)NCBIHuRef
CHM1_12062,513,489 - 62,564,783 (+)NCBICHM1_1
T2T-CHM13v2.02065,800,894 - 65,853,046 (+)NCBIT2T-CHM13v2.0
Prpf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392181,243,112 - 181,297,454 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2181,233,661 - 181,297,453 (+)EnsemblGRCm39 Ensembl
GRCm382181,601,319 - 181,655,661 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2181,591,868 - 181,655,660 (+)EnsemblGRCm38mm10GRCm38
MGSCv372181,336,024 - 181,390,366 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362181,530,799 - 181,585,067 (+)NCBIMGSCv36mm8
Celera2185,682,918 - 185,737,812 (+)NCBICelera
Cytogenetic Map2H4NCBI
cM Map2103.67NCBI
Prpf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83189,084,465 - 189,148,705 (+)NCBIGRCr8
mRatBN7.23168,706,952 - 168,771,191 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3168,704,299 - 168,774,991 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3173,086,155 - 173,150,690 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03182,045,248 - 182,109,782 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03178,707,876 - 178,772,145 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03177,098,137 - 177,162,937 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3177,098,073 - 177,162,916 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03180,807,600 - 180,871,661 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43170,740,406 - 170,804,674 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13170,646,458 - 170,710,709 (+)NCBI
Celera3163,816,537 - 163,880,658 (-)NCBICelera
Cytogenetic Map3q43NCBI
PRPF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22169,800,307 - 69,850,708 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12069,792,317 - 69,842,719 (+)NCBINHGRI_mPanPan1
PanPan1.12061,899,076 - 61,948,088 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2061,899,076 - 61,948,088 (+)Ensemblpanpan1.1panPan2
PRPF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12447,439,210 - 47,483,531 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2447,433,130 - 47,483,522 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2446,572,911 - 46,617,337 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02448,578,493 - 48,622,460 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2448,581,925 - 48,622,458 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12447,422,699 - 47,467,056 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02447,547,594 - 47,591,550 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02448,286,014 - 48,330,440 (+)NCBIUU_Cfam_GSD_1.0
Prpf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640195,721,774 - 195,767,285 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493651411,175,526 - 11,220,241 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493651411,175,410 - 11,220,928 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRPF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1762,815,085 - 62,858,382 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11762,815,509 - 62,857,795 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
PRPF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12211,482 - 259,590 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2211,604 - 259,447 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605047,645,668 - 47,789,609 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013035   ⟹   ENSHGLP00000012898
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474129,601,047 - 29,664,054 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000013036   ⟹   ENSHGLP00000012899
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474129,601,175 - 29,663,971 (+)Ensembl
RefSeq Acc Id: XM_004841124   ⟹   XP_004841181
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474129,601,050 - 29,664,054 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004841181 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012898
GenBank Protein JAO03312 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004841181   ⟸   XM_004841124
- UniProtKB: A0A0P6K8U3 (UniProtKB/TrEMBL),   G5C8B0 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000012899   ⟸   ENSHGLT00000013036
RefSeq Acc Id: ENSHGLP00000012898   ⟸   ENSHGLT00000013035


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009222 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013035 ENTREZGENE
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
InterPro HAT UniProtKB/TrEMBL
  PRP1_N UniProtKB/TrEMBL
  Syf1-like UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  TPR_repeat UniProtKB/TrEMBL
KEGG Report hgl:101704761 UniProtKB/TrEMBL
NCBI Gene Prpf6 ENTREZGENE
PANTHER PTHR11246 UniProtKB/TrEMBL
  PTHR11246:SF1 UniProtKB/TrEMBL
Pfam PRP1_N UniProtKB/TrEMBL
  TPR_16 UniProtKB/TrEMBL
  TPR_19 UniProtKB/TrEMBL
SMART HAT UniProtKB/TrEMBL
  TPR UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/TrEMBL
UniProt A0A0P6K8U3 ENTREZGENE, UniProtKB/TrEMBL
  G5C8B0 ENTREZGENE, UniProtKB/TrEMBL