Bpifa1 (BPI fold containing family A member 1) - Rat Genome Database

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Gene: Bpifa1 (BPI fold containing family A member 1) Heterocephalus glaber
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Symbol: Bpifa1
Name: BPI fold containing family A member 1
RGD ID: 18910147
Description: ENCODES a protein that exhibits lipid binding (inferred); INVOLVED IN killing of cells of another organism (ortholog); multicellular organismal-level water homeostasis (ortholog); positive regulation of acute inflammatory response (ortholog); ASSOCIATED WITH fetal alcohol spectrum disorder (ortholog); glutathione synthetase deficiency (ortholog); glutatione synthetase deficiency with 5-oxoprolinuria (ortholog); FOUND IN extracellular space (ortholog); microvillus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: BPI fold-containing family A member 1; Protein Plunc
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248426,024,460 - 6,031,718 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Bpifa1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248426,024,460 - 6,031,718 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
BPIFA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382033,235,996 - 33,243,306 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2033,235,995 - 33,243,311 (+)EnsemblGRCh38hg38GRCh38
GRCh372031,823,802 - 31,831,112 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362031,287,463 - 31,294,773 (+)NCBINCBI36Build 36hg18NCBI36
Build 342031,287,462 - 31,294,772NCBI
Celera2028,577,699 - 28,585,012 (+)NCBICelera
Cytogenetic Map20q11.21NCBI
HuRef2028,611,406 - 28,618,725 (+)NCBIHuRef
CHM1_12031,724,914 - 31,732,227 (+)NCBICHM1_1
T2T-CHM13v2.02034,963,235 - 34,970,520 (+)NCBIT2T-CHM13v2.0
Bpifa1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392153,984,800 - 153,991,137 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2153,984,800 - 153,991,139 (+)EnsemblGRCm39 Ensembl
GRCm382154,142,880 - 154,149,217 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2154,142,880 - 154,149,219 (+)EnsemblGRCm38mm10GRCm38
MGSCv372153,968,616 - 153,974,953 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362153,834,326 - 153,840,658 (+)NCBIMGSCv36mm8
Celera2160,065,103 - 160,071,425 (+)NCBICelera
Cytogenetic Map2H1NCBI
cM Map276.15NCBI
Bpifa1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83163,087,965 - 163,093,708 (+)NCBIGRCr8
mRatBN7.23142,627,810 - 142,633,553 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3142,627,810 - 142,633,552 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3146,529,706 - 146,535,449 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03155,113,544 - 155,119,287 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03152,853,782 - 152,859,525 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03149,624,867 - 149,630,610 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3149,624,712 - 149,630,613 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03156,002,440 - 156,008,183 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43144,529,855 - 144,535,598 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13144,435,476 - 144,441,219 (+)NCBI
Celera3141,369,225 - 141,374,968 (+)NCBICelera
Cytogenetic Map3q41NCBI
Bpifa1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542228,063,077 - 28,069,939 (-)NCBIChiLan1.0ChiLan1.0
BPIFA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22138,929,074 - 38,936,568 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12038,922,172 - 38,929,666 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02029,524,619 - 29,532,996 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12030,641,138 - 30,649,515 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2030,642,191 - 30,649,515 (+)Ensemblpanpan1.1panPan2
BPIFA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12422,475,407 - 22,482,666 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2422,457,631 - 22,482,661 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2422,121,008 - 22,128,270 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02423,161,382 - 23,168,638 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2423,160,932 - 23,168,633 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12422,436,703 - 22,443,958 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02422,546,960 - 22,554,221 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02422,978,118 - 22,985,370 (+)NCBIUU_Cfam_GSD_1.0
BPIFA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1736,754,498 - 36,761,621 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11736,754,498 - 36,761,622 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21741,704,827 - 41,711,955 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BPIFA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1237,571,577 - 37,579,529 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl237,573,837 - 37,578,667 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605089,321,049 - 89,329,502 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_021246909   ⟹   XP_021102568
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248426,025,719 - 6,031,718 (-)NCBI
RefSeq Acc Id: XM_021246910   ⟹   XP_021102569
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248426,024,460 - 6,031,718 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021102568 (Get FASTA)   NCBI Sequence Viewer  
  XP_021102569 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB11311 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000009295
GenBank Protein JAO00118 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021102569   ⟸   XM_021246910
- Peptide Label: isoform X2
- UniProtKB: A0AAX6S2A6 (UniProtKB/TrEMBL),   G5BPV3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021102568   ⟸   XM_021246909
- Peptide Label: isoform X1
- UniProtKB: A0AAX6S385 (UniProtKB/TrEMBL),   G5BPV3 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006666 ENTREZGENE
Ensembl Transcript ENSHGLT00000009395 ENTREZGENE
InterPro Bactericidal_perm-incr_a/b_dom UniProtKB/TrEMBL
  BPI_fold-superfamily_member UniProtKB/TrEMBL
  Lipid-bd_serum_glycop_N UniProtKB/TrEMBL
NCBI Gene Bpifa1 ENTREZGENE
PANTHER BPI FOLD-CONTAINING FAMILY A MEMBER 1 UniProtKB/TrEMBL
  PTHR47015:SF1 UniProtKB/TrEMBL
Pfam LBP_BPI_CETP UniProtKB/TrEMBL
Superfamily-SCOP SSF55394 UniProtKB/TrEMBL
UniProt A0AAX6S2A6 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6S385 ENTREZGENE, UniProtKB/TrEMBL
  G5BPV3 ENTREZGENE, UniProtKB/TrEMBL