P2rx5 (purinergic receptor P2X 5) - Rat Genome Database

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Gene: P2rx5 (purinergic receptor P2X 5) Heterocephalus glaber
Analyze
Symbol: P2rx5
Name: purinergic receptor P2X 5
RGD ID: 18910064
Description: ENCODES a protein that exhibits ATP-gated ion channel activity (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN chloride transport (ortholog); excitatory postsynaptic potential (ortholog); monoatomic cation transmembrane transport (ortholog); ASSOCIATED WITH Canavan disease (ortholog); genetic disease (ortholog); FOUND IN cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: P2X purinoceptor 5; purinergic receptor P2X, ligand-gated ion channel, 5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247866,327,419 - 6,342,980 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247866,327,132 - 6,343,040 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (ISO)
membrane  (IEA)
plasma membrane  (IEA)
postsynapse  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
P2rx5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247866,327,419 - 6,342,980 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247866,327,132 - 6,343,040 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
P2RX5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38173,673,227 - 3,696,155 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl173,672,199 - 3,696,240 (-)EnsemblGRCh38hg38GRCh38
GRCh37173,576,521 - 3,599,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36173,523,270 - 3,546,332 (-)NCBINCBI36Build 36hg18NCBI36
Build 34173,523,272 - 3,546,332NCBI
Celera173,590,263 - 3,611,320 (-)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef173,468,232 - 3,490,048 (-)NCBIHuRef
CHM1_1173,587,157 - 3,608,787 (-)NCBICHM1_1
T2T-CHM13v2.0173,562,283 - 3,584,749 (-)NCBIT2T-CHM13v2.0
P2rx5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391173,029,164 - 73,063,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1173,051,247 - 73,063,511 (+)EnsemblGRCm39 Ensembl
GRCm381173,155,389 - 73,172,687 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1173,160,421 - 73,172,685 (+)EnsemblGRCm38mm10GRCm38
MGSCv371172,974,032 - 72,986,189 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361172,976,720 - 72,988,880 (+)NCBIMGSCv36mm8
Celera1180,697,612 - 80,709,777 (+)NCBICelera
Cytogenetic Map11B4NCBI
cM Map1145.25NCBI
P2rx5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81058,276,329 - 58,291,108 (+)NCBIGRCr8
mRatBN7.21057,777,737 - 57,789,426 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1057,777,819 - 57,789,423 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1062,433,638 - 62,445,218 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01061,922,089 - 61,933,678 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01057,421,249 - 57,432,831 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01059,725,438 - 59,737,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1059,725,398 - 59,737,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01059,464,489 - 59,476,098 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41060,036,074 - 60,047,683 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11060,049,703 - 60,061,303 (+)NCBI
Celera1056,901,047 - 56,912,634 (+)NCBICelera
Cytogenetic Map10q24NCBI
P2rx5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546713,126,116 - 13,139,768 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546713,125,710 - 13,140,031 (+)NCBIChiLan1.0ChiLan1.0
P2RX5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21911,281,816 - 11,307,884 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11713,247,323 - 13,273,351 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0173,722,117 - 3,745,833 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1173,720,232 - 3,735,656 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl173,719,457 - 3,739,709 (-)Ensemblpanpan1.1panPan2
P2RX5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1947,500,593 - 47,516,790 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha946,662,847 - 46,679,019 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0948,345,924 - 48,362,108 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl948,345,926 - 48,362,078 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1947,123,686 - 47,139,818 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0947,412,831 - 47,428,998 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0947,468,460 - 47,484,856 (-)NCBIUU_Cfam_GSD_1.0
P2rx5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560255,515,339 - 55,530,836 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936677370,138 - 385,649 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936677370,141 - 385,669 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
P2RX5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1249,778,800 - 49,796,110 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11249,780,241 - 49,796,287 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21251,643,316 - 51,649,939 (-)NCBISscrofa10.2Sscrofa10.2susScr3
P2RX5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1163,173,215 - 3,198,262 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl163,180,595 - 3,196,341 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605918,597,921 - 18,612,118 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004857228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021238140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002386927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01062114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000017053   ⟹   ENSHGLP00000016882
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247866,327,419 - 6,342,980 (-)Ensembl
RefSeq Acc Id: XM_004857228   ⟹   XP_004857285
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,038 (-)NCBI
RefSeq Acc Id: XM_021238133   ⟹   XP_021093792
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,040 (-)NCBI
RefSeq Acc Id: XM_021238134   ⟹   XP_021093793
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,039 (-)NCBI
RefSeq Acc Id: XM_021238135   ⟹   XP_021093794
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,040 (-)NCBI
RefSeq Acc Id: XM_021238136   ⟹   XP_021093795
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,040 (-)NCBI
RefSeq Acc Id: XM_021238137   ⟹   XP_021093796
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,039 (-)NCBI
RefSeq Acc Id: XM_021238138   ⟹   XP_021093797
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,040 (-)NCBI
RefSeq Acc Id: XM_021238139   ⟹   XP_021093798
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,343,020 (-)NCBI
RefSeq Acc Id: XM_021238140   ⟹   XP_021093799
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,330,205 - 6,339,034 (-)NCBI
RefSeq Acc Id: XR_002386921
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,327,132 - 6,343,040 (-)NCBI
RefSeq Acc Id: XR_002386922
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,327,132 - 6,343,040 (-)NCBI
RefSeq Acc Id: XR_002386923
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,327,132 - 6,343,040 (-)NCBI
RefSeq Acc Id: XR_002386924
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,332,030 - 6,343,040 (-)NCBI
RefSeq Acc Id: XR_002386925
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,332,044 - 6,343,040 (-)NCBI
RefSeq Acc Id: XR_002386926
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,332,030 - 6,343,040 (-)NCBI
RefSeq Acc Id: XR_002386927
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247866,332,926 - 6,343,040 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021093797   ⟸   XM_021238138
- Peptide Label: isoform X6
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093795   ⟸   XM_021238136
- Peptide Label: isoform X4
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093794   ⟸   XM_021238135
- Peptide Label: isoform X3
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093792   ⟸   XM_021238133
- Peptide Label: isoform X1
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093796   ⟸   XM_021238137
- Peptide Label: isoform X5
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093793   ⟸   XM_021238134
- Peptide Label: isoform X2
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004857285   ⟸   XM_004857228
- Peptide Label: isoform X8
- UniProtKB: G5B933 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021093798   ⟸   XM_021238139
- Peptide Label: isoform X7
RefSeq Acc Id: XP_021093799   ⟸   XM_021238140
- Peptide Label: isoform X9
RefSeq Acc Id: ENSHGLP00000016882   ⟸   ENSHGLT00000017053


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012071 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017053 ENTREZGENE
Gene3D-CATH atp-gated p2x4 ion channel UniProtKB/TrEMBL
  atp-gated p2x4 ion channel domain UniProtKB/TrEMBL
InterPro P2X5_purnocptor UniProtKB/TrEMBL
  P2X_extracellular_dom_sf UniProtKB/TrEMBL
  P2X_purnocptor UniProtKB/TrEMBL
NCBI Gene P2rx5 ENTREZGENE
PANTHER P2X PURINOCEPTOR UniProtKB/TrEMBL
  P2X PURINOCEPTOR 5 UniProtKB/TrEMBL
Pfam P2X_receptor UniProtKB/TrEMBL
PIRSF P2X_purinoceptor UniProtKB/TrEMBL
PRINTS P2X5RECEPTOR UniProtKB/TrEMBL
  P2XRECEPTOR UniProtKB/TrEMBL
PROSITE P2X_RECEPTOR UniProtKB/TrEMBL
UniProt G5B933 ENTREZGENE, UniProtKB/TrEMBL