Ca14 (carbonic anhydrase 14) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Ca14 (carbonic anhydrase 14) Heterocephalus glaber
Analyze
Symbol: Ca14
Name: carbonic anhydrase 14
RGD ID: 18909942
Description: ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); INVOLVED IN one-carbon metabolic process (inferred); ASSOCIATED WITH gastrointestinal stromal tumor (ortholog); genetic disease (ortholog); immunodeficiency 42 (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,012,280 - 18,022,508 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,011,094 - 18,018,585 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Ca14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477218,012,280 - 18,022,508 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477218,011,094 - 18,018,585 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CA14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381150,257,774 - 150,265,078 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1150,257,251 - 150,265,078 (+)EnsemblGRCh38hg38GRCh38
GRCh371150,230,169 - 150,237,478 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,488,047 - 148,504,102 (+)NCBINCBI36Build 36hg18NCBI36
Build 341147,043,290 - 147,050,549NCBI
Celera1123,345,949 - 123,353,209 (+)NCBICelera
Cytogenetic Map1q21.2NCBI
HuRef1121,608,885 - 121,616,145 (+)NCBIHuRef
CHM1_11151,625,949 - 151,633,204 (+)NCBICHM1_1
T2T-CHM13v2.01149,382,687 - 149,389,995 (+)NCBIT2T-CHM13v2.0
Car14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39395,805,080 - 95,812,443 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl395,805,080 - 95,812,003 (-)EnsemblGRCm39 Ensembl
GRCm38395,897,768 - 95,905,117 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl395,897,768 - 95,904,691 (-)EnsemblGRCm38mm10GRCm38
MGSCv37395,701,723 - 95,708,562 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36395,983,205 - 95,990,044 (-)NCBIMGSCv36mm8
Celera397,331,353 - 97,338,218 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map341.48NCBI
Car14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82186,131,196 - 186,138,164 (-)NCBIGRCr8
mRatBN7.22183,442,263 - 183,449,231 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2183,441,667 - 183,449,693 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2191,107,404 - 191,113,724 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02188,910,980 - 188,917,289 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02183,739,941 - 183,746,261 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02198,010,142 - 198,017,635 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2198,010,349 - 198,016,898 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02217,500,302 - 217,507,935 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42190,683,916 - 190,690,229 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera2175,971,924 - 175,978,237 (-)NCBICelera
Cytogenetic Map2q34NCBI
Ca14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955413510,089 - 516,892 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955413510,089 - 516,892 (-)NCBIChiLan1.0ChiLan1.0
CA14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2199,573,623 - 99,583,732 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1199,327,600 - 99,334,890 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01125,602,521 - 125,610,323 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11129,253,787 - 129,261,676 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1129,253,787 - 129,261,676 (+)Ensemblpanpan1.1panPan2
CA14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11759,504,181 - 59,510,497 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1759,504,483 - 59,510,127 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1758,950,038 - 58,956,854 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01760,519,100 - 60,525,928 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1760,519,842 - 60,525,928 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11759,349,547 - 59,356,380 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01759,433,284 - 59,440,110 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01760,161,286 - 60,168,105 (+)NCBIUU_Cfam_GSD_1.0
Ca14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505821,514,788 - 21,521,689 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936580544,852 - 555,089 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936580545,221 - 552,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl498,821,579 - 98,828,736 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1498,821,577 - 98,828,934 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CA14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366603813,026,361 - 13,034,889 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013059   ⟹   ENSHGLP00000012922
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462477218,012,280 - 18,022,508 (+)Ensembl
RefSeq Acc Id: XM_004853963   ⟹   XP_004854020
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477218,011,508 - 18,018,585 (+)NCBI
RefSeq Acc Id: XM_013075574   ⟹   XP_012931028
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462477218,011,094 - 18,018,585 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004854020 (Get FASTA)   NCBI Sequence Viewer  
  XP_012931028 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08593 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012922
  ENSHGLP00000048743
  ENSHGLP00100031306
Reference Protein Sequences
RefSeq Acc Id: XP_012931028   ⟸   XM_013075574
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004854020   ⟸   XM_004853963
- Peptide Label: isoform X1
- UniProtKB: G5BH32 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000012922   ⟸   ENSHGLT00000013059


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009239 Ensembl, ENTREZGENE
  ENSHGLG00000035588 UniProtKB/TrEMBL
  ENSHGLG00100034641 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000013059 ENTREZGENE
  ENSHGLT00000086224 UniProtKB/TrEMBL
  ENSHGLT00100070358 UniProtKB/TrEMBL
Gene3D-CATH 3.10.200.10 UniProtKB/TrEMBL
InterPro CA_dom UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/TrEMBL
KEGG Report hgl:101718354 UniProtKB/TrEMBL
NCBI Gene Ca14 ENTREZGENE
PANTHER PTHR18952 UniProtKB/TrEMBL
  PTHR18952:SF84 UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/TrEMBL
PROSITE ALPHA_CA_2 UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/TrEMBL
UniProt G5BH32 ENTREZGENE, UniProtKB/TrEMBL