Nsun3 (NOP2/Sun RNA methyltransferase 3) - Rat Genome Database

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Gene: Nsun3 (NOP2/Sun RNA methyltransferase 3) Heterocephalus glaber
Analyze
Symbol: Nsun3
Name: NOP2/Sun RNA methyltransferase 3
RGD ID: 18909923
Description: ENCODES a protein that exhibits tRNA (cytidine-5-)-methyltransferase activity (ortholog); INVOLVED IN regulation of mitochondrial translation (ortholog); tRNA wobble base cytosine methylation (ortholog); ASSOCIATED WITH autosomal recessive thrombophilia due to protein S deficiency (ortholog); combined oxidative phosphorylation deficiency 48 (ortholog); genetic disease (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: NOP2/Sun RNA methyltransferase family member 3; Putative methyltransferase NSUN3; tRNA (cytosine(34)-C(5))-methyltransferase, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247896,787,234 - 6,846,201 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247896,787,255 - 6,853,438 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Nsun3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247896,787,234 - 6,846,201 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247896,787,255 - 6,853,438 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
NSUN3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38394,063,061 - 94,131,832 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl394,062,980 - 94,131,832 (+)EnsemblGRCh38hg38GRCh38
GRCh37393,781,905 - 93,850,676 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36395,264,545 - 95,328,320 (+)NCBINCBI36Build 36hg18NCBI36
Build 34395,264,544 - 95,328,320NCBI
Celera392,165,741 - 92,229,276 (+)NCBICelera
Cytogenetic Map3q11.2NCBI
HuRef391,144,472 - 91,208,238 (+)NCBIHuRef
CHM1_1393,744,859 - 93,808,667 (+)NCBICHM1_1
T2T-CHM13v2.0396,761,512 - 96,830,315 (+)NCBIT2T-CHM13v2.0
Nsun3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391662,552,807 - 62,607,238 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1662,552,807 - 62,607,181 (-)EnsemblGRCm39 Ensembl
GRCm381662,732,444 - 62,786,884 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1662,732,444 - 62,786,818 (-)EnsemblGRCm38mm10GRCm38
MGSCv371662,734,678 - 62,786,542 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361662,674,701 - 62,729,014 (-)NCBIMGSCv36mm8
Celera1663,043,633 - 63,095,414 (-)NCBICelera
Cytogenetic Map16C1.3NCBI
cM Map1636.43NCBI
Nsun3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,960,187 - 51,062,366 (+)NCBIGRCr8
mRatBN7.21137,490,832 - 37,575,607 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1137,490,838 - 37,568,543 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01138,535,971 - 38,590,274 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,536,165 - 38,590,107 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0164,370,946 - 64,455,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41138,158,332 - 38,234,163 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1137,368,514 - 37,444,379 (+)NCBICelera
Cytogenetic Map11q12NCBI
Nsun3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554073,342,876 - 3,397,150 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554073,322,246 - 3,397,289 (-)NCBIChiLan1.0ChiLan1.0
NSUN3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2291,974,964 - 92,046,645 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1391,979,752 - 92,051,217 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0391,128,431 - 91,203,337 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1397,807,732 - 97,878,472 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl397,807,732 - 97,878,472 (+)Ensemblpanpan1.1panPan2
NSUN3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1331,774,908 - 1,826,948 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl331,774,834 - 1,826,677 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha331,954,043 - 2,009,176 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0331,873,915 - 1,929,118 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl331,873,966 - 1,928,298 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1331,782,555 - 1,837,657 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0331,817,903 - 1,873,015 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0332,042,811 - 2,097,960 (+)NCBIUU_Cfam_GSD_1.0
Nsun3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602155,276,921 - 155,332,142 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936666185,231 - 236,193 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936666183,536 - 236,580 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NSUN3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13165,765,502 - 165,823,171 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113165,763,896 - 165,823,182 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213176,447,513 - 176,506,860 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NSUN3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12286,576,985 - 86,643,030 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2286,577,280 - 86,642,653 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604180,039,580 - 80,232,612 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000008722   ⟹   ENSHGLP00000008629
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247896,787,234 - 6,846,201 (+)Ensembl
RefSeq Acc Id: XM_004857927   ⟹   XP_004857984
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247896,787,255 - 6,846,194 (+)NCBI
RefSeq Acc Id: XM_021238830   ⟹   XP_021094489
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247896,787,255 - 6,853,438 (+)NCBI
RefSeq Acc Id: XM_021238832   ⟹   XP_021094491
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247896,787,255 - 6,853,437 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004857984 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094489 (Get FASTA)   NCBI Sequence Viewer  
  XP_021094491 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14497 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008629
GenBank Protein JAN97512 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021094489   ⟸   XM_021238830
- Peptide Label: isoform X1
RefSeq Acc Id: XP_021094491   ⟸   XM_021238832
- Peptide Label: isoform X3
RefSeq Acc Id: XP_004857984   ⟸   XM_004857927
- Peptide Label: isoform X2
- UniProtKB: A0A0P6J4Q3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000008629   ⟸   ENSHGLT00000008722


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006224 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000008722 ENTREZGENE
Gene3D-CATH 3.40.50.150 UniProtKB/TrEMBL
  6.20.240.40 UniProtKB/TrEMBL
InterPro MeTrfase_RsmB-F_NOP2_cat UniProtKB/TrEMBL
  MeTrfase_RsmB/NOP2 UniProtKB/TrEMBL
  RCMT UniProtKB/TrEMBL
  SAM-dependent_MTases UniProtKB/TrEMBL
NCBI Gene Nsun3 ENTREZGENE
PANTHER PTHR22808 UniProtKB/TrEMBL
  TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE, MITOCHONDRIAL UniProtKB/TrEMBL
Pfam Methyltr_RsmB-F UniProtKB/TrEMBL
PRINTS RCMTFAMILY UniProtKB/TrEMBL
PROSITE SAM_MT_RSMB_NOP UniProtKB/TrEMBL
Superfamily-SCOP SSF53335 UniProtKB/TrEMBL
UniProt A0A0P6J4Q3 ENTREZGENE, UniProtKB/TrEMBL