Slc5a2 (solute carrier family 5 member 2) - Rat Genome Database

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Gene: Slc5a2 (solute carrier family 5 member 2) Heterocephalus glaber
Analyze
Symbol: Slc5a2
Name: solute carrier family 5 member 2
RGD ID: 18909876
Description: ENCODES a protein that exhibits glucose:sodium symporter activity (ortholog); INVOLVED IN glucose transmembrane transport (ortholog); negative regulation of urine volume (ortholog); renal potassium excretion (ortholog); PARTICIPATES IN sodium-glucose cotransporter mediated glucose transport pathway; ASSOCIATED WITH branched-chain keto acid dehydrogenase kinase deficiency (ortholog); genetic disease (ortholog); hypertension (ortholog); FOUND IN brush border membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: sodium/glucose cotransporter 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478214,483,822 - 14,490,841 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478214,484,532 - 14,490,598 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc5a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478214,483,822 - 14,490,841 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478214,484,532 - 14,490,598 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLC5A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381631,483,123 - 31,490,769 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1631,483,002 - 31,490,860 (+)EnsemblGRCh38hg38GRCh38
GRCh371631,494,444 - 31,502,090 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361631,401,940 - 31,409,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 341631,401,939 - 31,409,590NCBI
Celera1628,806,298 - 28,813,953 (-)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1629,054,639 - 29,062,297 (+)NCBIHuRef
CHM1_11632,813,088 - 32,820,740 (+)NCBICHM1_1
T2T-CHM13v2.01631,870,510 - 31,878,162 (+)NCBIT2T-CHM13v2.0
Slc5a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397127,864,855 - 127,871,602 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7127,864,829 - 127,871,602 (+)EnsemblGRCm39 Ensembl
GRCm387128,265,683 - 128,272,430 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7128,265,657 - 128,272,430 (+)EnsemblGRCm38mm10GRCm38
MGSCv377135,409,211 - 135,415,947 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367128,056,845 - 128,063,581 (+)NCBIMGSCv36mm8
Celera7128,101,772 - 128,108,508 (+)NCBICelera
Cytogenetic Map7F3NCBI
cM Map770.08NCBI
Slc5a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81192,277,621 - 192,283,742 (+)NCBIGRCr8
mRatBN7.21182,847,185 - 182,853,309 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1182,847,106 - 182,853,306 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1191,197,664 - 191,203,785 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01198,383,752 - 198,389,873 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01191,053,939 - 191,060,060 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01199,682,688 - 199,688,809 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1199,682,688 - 199,688,809 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01206,728,635 - 206,734,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41187,523,230 - 187,529,351 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11187,673,110 - 187,679,232 (+)NCBI
Celera1180,493,106 - 180,499,226 (+)NCBICelera
Cytogenetic Map1q37NCBI
Slc5a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554938,322,597 - 8,329,646 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554938,322,972 - 8,329,886 (+)NCBIChiLan1.0ChiLan1.0
SLC5A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21834,692,678 - 34,699,920 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11639,494,547 - 39,501,343 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01623,474,992 - 23,482,603 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11631,853,610 - 31,861,261 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1631,853,602 - 31,861,261 (+)Ensemblpanpan1.1panPan2
SLC5A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1616,765,935 - 16,772,145 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl616,765,938 - 16,772,137 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha618,393,645 - 18,399,844 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0616,890,717 - 16,896,969 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl616,890,717 - 16,905,803 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1616,694,325 - 16,700,565 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0616,614,024 - 16,620,201 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0616,925,700 - 16,931,900 (-)NCBIUU_Cfam_GSD_1.0
Slc5a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344125,693,244 - 125,699,926 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365438,336,873 - 8,343,322 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365438,336,884 - 8,343,322 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC5A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,081,141 - 17,089,568 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,081,138 - 17,089,422 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,348,680 - 17,354,123 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC5A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1528,183,141 - 28,191,352 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl528,183,618 - 28,191,120 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660681,248,831 - 1,257,049 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017278   ⟹   ENSHGLP00000017107
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478214,483,822 - 14,490,841 (+)Ensembl
RefSeq Acc Id: XM_004856259   ⟹   XP_004856316
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478214,484,532 - 14,490,598 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004856316 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017107
  ENSHGLP00100016063
GenBank Protein JAO00797 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004856316   ⟸   XM_004856259
- UniProtKB: A0A0P6K5Z9 (UniProtKB/TrEMBL),   G5BYB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000017107   ⟸   ENSHGLT00000017278


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012248 Ensembl, ENTREZGENE
  ENSHGLG00100011853 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017278 ENTREZGENE
  ENSHGLT00100016240 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1730.10 UniProtKB/TrEMBL
InterPro Na/Glc_symporter_sf UniProtKB/TrEMBL
  Na/solute_symporter UniProtKB/TrEMBL
  Na/solute_symporter_CS UniProtKB/TrEMBL
KEGG Report hgl:101723512 UniProtKB/TrEMBL
NCBI Gene Slc5a2 ENTREZGENE
PANTHER SODIUM/GLUCOSE COTRANSPORTER 2 UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 5 UniProtKB/TrEMBL
Pfam SSF UniProtKB/TrEMBL
PROSITE NA_SOLUT_SYMP_1 UniProtKB/TrEMBL
  NA_SOLUT_SYMP_2 UniProtKB/TrEMBL
  NA_SOLUT_SYMP_3 UniProtKB/TrEMBL
UniProt A0A0P6K5Z9 ENTREZGENE, UniProtKB/TrEMBL
  G5BYB8 ENTREZGENE, UniProtKB/TrEMBL