Padi4 (peptidyl arginine deiminase 4) - Rat Genome Database

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Gene: Padi4 (peptidyl arginine deiminase 4) Heterocephalus glaber
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Symbol: Padi4
Name: peptidyl arginine deiminase 4
RGD ID: 18909822
Description: ENCODES a protein that exhibits histone H3R17 arginine deiminase activity (ortholog); histone H3R2 arginine deiminase activity (ortholog); histone H3R26 arginine deiminase activity (ortholog); INVOLVED IN chromatin organization (ortholog); chromatin remodeling (ortholog); nucleosome assembly (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog); carcinoma (ortholog); chromosome 1p36 deletion syndrome (ortholog); FOUND IN protein-containing complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Protein-arginine deiminase type-4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,871,078 - 2,898,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,871,002 - 2,898,748 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Padi4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247642,871,078 - 2,898,584 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247642,871,002 - 2,898,748 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PADI4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38117,308,197 - 17,364,004 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl117,308,195 - 17,364,004 (+)EnsemblGRCh38hg38GRCh38
GRCh37117,634,692 - 17,690,499 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,507,279 - 17,563,082 (+)NCBINCBI36Build 36hg18NCBI36
Build 34117,379,997 - 17,435,801NCBI
Celera115,960,064 - 16,015,550 (+)NCBICelera
Cytogenetic Map1p36.13NCBI
HuRef115,880,966 - 15,936,461 (+)NCBIHuRef
CHM1_1117,743,078 - 17,796,994 (+)NCBICHM1_1
T2T-CHM13v2.0117,122,255 - 17,177,953 (+)NCBIT2T-CHM13v2.0
Padi4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394140,472,819 - 140,501,514 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4140,473,176 - 140,501,547 (-)EnsemblGRCm39 Ensembl
GRCm384140,745,508 - 140,774,239 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4140,745,865 - 140,774,236 (-)EnsemblGRCm38mm10GRCm38
MGSCv374140,301,423 - 140,330,118 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364140,017,941 - 140,046,261 (-)NCBIMGSCv36mm8
Celera4142,524,735 - 142,585,456 (-)NCBICelera
Cytogenetic Map4D3NCBI
cM Map472.34NCBI
Padi4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85158,324,417 - 158,357,466 (-)NCBIGRCr8
mRatBN7.25153,041,351 - 153,074,412 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5153,041,352 - 153,074,362 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5155,737,777 - 155,763,407 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05157,512,294 - 157,538,146 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05157,493,425 - 157,526,421 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05159,260,675 - 159,293,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5159,260,675 - 159,293,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05162,967,383 - 163,001,294 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45159,580,718 - 159,614,628 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15159,590,905 - 159,624,816 (-)NCBI
Celera5151,402,208 - 151,435,173 (-)NCBICelera
Cytogenetic Map5q36NCBI
Padi4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555271,536,423 - 1,561,130 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555271,536,917 - 1,560,508 (-)NCBIChiLan1.0ChiLan1.0
PADI4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21209,762,880 - 209,818,433 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11208,881,845 - 208,937,319 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0116,255,680 - 16,311,256 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1117,311,436 - 17,365,670 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl117,311,436 - 17,365,426 (+)Ensemblpanpan1.1panPan2
PADI4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1280,912,814 - 80,942,767 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl280,905,391 - 80,993,973 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha277,450,334 - 77,480,310 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0281,560,676 - 81,590,655 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl281,560,677 - 81,641,599 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1278,313,557 - 78,343,545 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0279,329,140 - 79,359,110 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0280,398,999 - 80,428,932 (-)NCBIUU_Cfam_GSD_1.0
Padi4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505838,394,401 - 38,414,845 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364744,221,672 - 4,238,599 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364744,219,183 - 4,239,551 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PADI4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl675,935,889 - 75,966,293 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1675,935,909 - 75,966,275 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2670,279,760 - 70,310,373 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PADI4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120115,212,214 - 115,262,634 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20115,212,254 - 115,262,581 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666033849,828 - 904,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


RefSeq Acc Id: ENSHGLT00000025850   ⟹   ENSHGLP00000025623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247642,871,078 - 2,898,584 (+)Ensembl
RefSeq Acc Id: XM_004850390   ⟹   XP_004850447
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247642,871,078 - 2,898,748 (+)NCBI
RefSeq Acc Id: XM_021262909   ⟹   XP_021118568
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247642,871,002 - 2,898,748 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004850447 (Get FASTA)   NCBI Sequence Viewer  
  XP_021118568 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14743 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025623
RefSeq Acc Id: XP_021118568   ⟸   XM_021262909
- Peptide Label: isoform X2
- UniProtKB: G5BZN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004850447   ⟸   XM_004850390
- Peptide Label: isoform X1
- UniProtKB: G5BZN2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000025623   ⟸   ENSHGLT00000025850


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018245 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025850 ENTREZGENE
Gene3D-CATH Protein-arginine deiminase, central domain UniProtKB/TrEMBL
  Protein-arginine deiminase, N-terminal domain UniProtKB/TrEMBL
InterPro Cupredoxin UniProtKB/TrEMBL
  PAD UniProtKB/TrEMBL
  PAD_C UniProtKB/TrEMBL
  PAD_central_sf UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
  PAD_N_sf UniProtKB/TrEMBL
  Prot_Arg_deaminase_cen_dom UniProtKB/TrEMBL
NCBI Gene Padi4 ENTREZGENE
PANTHER PEPTIDYLARGININE DEIMINASE UniProtKB/TrEMBL
  PROTEIN-ARGININE DEIMINASE TYPE-4 UniProtKB/TrEMBL
Pfam PAD UniProtKB/TrEMBL
  PAD_M UniProtKB/TrEMBL
  PAD_N UniProtKB/TrEMBL
PIRSF Protein-arginine_deiminase UniProtKB/TrEMBL
Superfamily-SCOP Cupredoxins UniProtKB/TrEMBL
  Pentein UniProtKB/TrEMBL
  Peptidylarginine deiminase Pad4, middle domain UniProtKB/TrEMBL
UniProt G5BZN2 ENTREZGENE, UniProtKB/TrEMBL