Riok2 (RIO kinase 2) - Rat Genome Database

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Gene: Riok2 (RIO kinase 2) Heterocephalus glaber
Analyze
Symbol: Riok2
Name: RIO kinase 2
RGD ID: 18909768
Description: ENCODES a protein that exhibits ATP binding (inferred); protein kinase activity (inferred); protein serine/threonine kinase activity (inferred); INVOLVED IN positive regulation of ribosomal small subunit export from nucleus (ortholog); positive regulation of rRNA processing (ortholog); regulation of mitotic metaphase/anaphase transition (ortholog); PARTICIPATES IN ribosome biogenesis pathway; ASSOCIATED WITH familial adenomatous polyposis 1 (ortholog); genetic disease (ortholog); Hereditary Neoplastic Syndromes (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Serine/threonine-protein kinase RIO2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474315,808,445 - 15,828,415 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Riok2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474315,808,445 - 15,828,415 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RIOK2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38597,160,867 - 97,183,247 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl597,160,867 - 97,183,247 (-)EnsemblGRCh38hg38GRCh38
GRCh37596,496,571 - 96,518,951 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36596,524,397 - 96,544,700 (-)NCBINCBI36Build 36hg18NCBI36
Build 34596,524,396 - 96,544,700NCBI
Celera592,380,971 - 92,403,748 (-)NCBICelera
Cytogenetic Map5q15NCBI
HuRef591,686,274 - 91,709,022 (-)NCBIHuRef
CHM1_1595,929,175 - 95,951,630 (-)NCBICHM1_1
T2T-CHM13v2.0597,661,631 - 97,684,062 (-)NCBIT2T-CHM13v2.0
Riok2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391717,594,594 - 17,615,161 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1717,594,571 - 17,615,161 (+)EnsemblGRCm39 Ensembl
GRCm381717,374,332 - 17,394,899 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1717,374,309 - 17,394,899 (+)EnsemblGRCm38mm10GRCm38
MGSCv371717,511,296 - 17,531,863 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361717,074,154 - 17,098,589 (+)NCBIMGSCv36mm8
Celera1718,322,390 - 18,343,205 (+)NCBICelera
Cytogenetic Map17A3.2NCBI
cM Map179.77NCBI
Riok2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8166,776,215 - 66,792,480 (+)NCBIGRCr8
mRatBN7.2158,103,132 - 58,119,397 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl158,103,084 - 58,120,512 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx162,941,961 - 62,958,386 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0171,633,479 - 71,649,966 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0164,851,986 - 64,868,412 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0159,130,008 - 59,146,457 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl159,129,951 - 59,146,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0160,057,339 - 60,073,788 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4155,897,247 - 55,913,533 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1155,900,191 - 55,916,476 (+)NCBI
Celera154,297,817 - 54,314,118 (+)NCBICelera
Cytogenetic Map1q12NCBI
Riok2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541815,487,248 - 15,513,831 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541815,487,248 - 15,509,490 (+)NCBIChiLan1.0ChiLan1.0
RIOK2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2492,412,899 - 92,433,579 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1590,566,534 - 90,587,226 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0592,473,239 - 92,494,763 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1598,026,237 - 98,048,360 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl598,028,426 - 98,048,256 (-)Ensemblpanpan1.1panPan2
RIOK2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1312,548,830 - 12,571,312 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl312,548,847 - 12,571,298 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha313,888,964 - 13,911,359 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0312,432,261 - 12,454,732 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl312,432,300 - 12,456,110 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1312,386,660 - 12,409,131 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0312,387,940 - 12,410,400 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0312,587,610 - 12,610,085 (+)NCBIUU_Cfam_GSD_1.0
Riok2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213168,108,339 - 168,128,473 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365236,293,710 - 6,314,999 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365236,293,735 - 6,313,840 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RIOK2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.12103,802,044 - 103,823,566 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22107,632,269 - 107,655,935 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RIOK2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1490,992,940 - 91,010,016 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl490,996,371 - 91,010,036 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604939,647,567 - 39,671,772 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004841726   ⟹   XP_004841783
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474315,808,445 - 15,828,415 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004841783 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15950 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000012778
GenBank Protein JAN98255 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004841783   ⟸   XM_004841726
- UniProtKB: A0A0P6K281 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009139 ENTREZGENE
Ensembl Transcript ENSHGLT00000012915 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Rio2 UniProtKB/TrEMBL
  RIO2_wHTH_N UniProtKB/TrEMBL
  RIO_kinase UniProtKB/TrEMBL
  RIO_kinase_CS UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
NCBI Gene Riok2 ENTREZGENE
PANTHER SER/THR-PROTEIN KINASE RIO2 UniProtKB/TrEMBL
  SERINE/THREONINE-PROTEIN KINASE RIO2 UniProtKB/TrEMBL
Pfam RIO1 UniProtKB/TrEMBL
  Rio2_N UniProtKB/TrEMBL
PROSITE RIO1 UniProtKB/TrEMBL
SMART RIO UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0P6K281 ENTREZGENE, UniProtKB/TrEMBL