Osgin2 (oxidative stress induced growth inhibitor family member 2) - Rat Genome Database

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Gene: Osgin2 (oxidative stress induced growth inhibitor family member 2) Heterocephalus glaber
Analyze
Symbol: Osgin2
Name: oxidative stress induced growth inhibitor family member 2
RGD ID: 18909617
Description: ENCODES a protein that exhibits growth factor activity (inferred); INVOLVED IN negative regulation of cell growth (inferred); signal transduction (inferred); ASSOCIATED WITH genetic disease (ortholog); Nijmegen breakage syndrome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Oxidative stress-induced growth inhibitor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247442,070,775 - 2,091,549 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:21993625  


Genomics

Comparative Map Data
Osgin2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247442,070,775 - 2,091,549 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
OSGIN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38889,901,868 - 89,927,888 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl889,901,849 - 89,927,888 (+)EnsemblGRCh38hg38GRCh38
GRCh37890,914,096 - 90,940,116 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36890,983,269 - 91,009,271 (+)NCBINCBI36Build 36hg18NCBI36
Build 34890,983,268 - 91,009,271NCBI
Celera887,108,907 - 87,134,906 (+)NCBICelera
Cytogenetic Map8q21.3NCBI
HuRef886,124,270 - 86,150,270 (+)NCBIHuRef
CHM1_1890,955,027 - 90,981,021 (+)NCBICHM1_1
T2T-CHM13v2.0891,025,051 - 91,051,069 (+)NCBIT2T-CHM13v2.0
Osgin2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39415,996,354 - 16,015,266 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl415,997,121 - 16,013,888 (-)EnsemblGRCm39 Ensembl
GRCm38415,996,354 - 16,015,258 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl415,997,121 - 16,013,888 (-)EnsemblGRCm38mm10GRCm38
MGSCv37415,924,268 - 15,941,024 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36415,924,268 - 15,941,024 (-)NCBIMGSCv36mm8
Celera415,800,419 - 15,817,277 (-)NCBICelera
Cytogenetic Map4A2NCBI
cM Map46.66NCBI
Osgin2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8534,297,417 - 34,316,353 (-)NCBIGRCr8
mRatBN7.2529,500,406 - 29,519,340 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl529,500,408 - 29,520,831 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx531,656,853 - 31,675,705 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0533,249,519 - 33,268,371 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0533,209,699 - 33,228,549 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0529,663,131 - 29,683,634 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl529,663,685 - 29,682,005 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0534,341,646 - 34,361,956 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4530,582,447 - 30,601,332 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1530,582,407 - 30,601,836 (-)NCBI
Celera528,705,683 - 28,726,264 (-)NCBICelera
Cytogenetic Map5q13NCBI
Osgin2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554176,816,346 - 6,833,810 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554176,816,348 - 6,833,257 (+)NCBIChiLan1.0ChiLan1.0
OSGIN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27107,297,549 - 107,322,521 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1882,837,201 - 82,862,192 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0886,590,912 - 86,616,817 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1888,543,550 - 88,569,609 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl888,543,550 - 88,569,069 (+)Ensemblpanpan1.1panPan2
OSGIN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12935,386,817 - 35,405,133 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2935,390,259 - 35,404,269 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2935,534,147 - 35,557,301 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02935,579,176 - 35,602,495 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2935,578,475 - 35,602,018 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12935,570,328 - 35,593,670 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02935,591,068 - 35,614,314 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02936,024,837 - 36,048,581 (+)NCBIUU_Cfam_GSD_1.0
Osgin2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530344,030,169 - 44,055,294 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365443,737,412 - 3,761,555 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365443,737,417 - 3,762,536 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSGIN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl446,886,968 - 46,912,255 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1446,886,961 - 46,912,941 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2451,350,644 - 51,376,596 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OSGIN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1884,986,109 - 85,011,312 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl884,987,441 - 85,013,933 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603955,868,175 - 55,893,307 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004841965   ⟹   XP_004842022
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,070,775 - 2,090,727 (-)NCBI
RefSeq Acc Id: XM_013071195   ⟹   XP_012926649
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,070,775 - 2,091,549 (-)NCBI
RefSeq Acc Id: XM_021255965   ⟹   XP_021111624
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247442,070,775 - 2,088,394 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004842022 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926649 (Get FASTA)   NCBI Sequence Viewer  
  XP_021111624 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB06699 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024778
  ENSHGLP00000043590
Reference Protein Sequences
RefSeq Acc Id: XP_012926649   ⟸   XM_013071195
- Peptide Label: isoform X2
- UniProtKB: G5BBN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004842022   ⟸   XM_004841965
- Peptide Label: isoform X1
- UniProtKB: G5BBN8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021111624   ⟸   XM_021255965
- Peptide Label: isoform X2
- UniProtKB: G5BBN8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017665 ENTREZGENE
  ENSHGLG00000039904 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000025000 ENTREZGENE
  ENSHGLT00000052429 UniProtKB/TrEMBL
Gene3D-CATH FAD/NAD(P)-binding domain UniProtKB/TrEMBL
InterPro FAD/NAD-bd_sf UniProtKB/TrEMBL
  OKL38_fam UniProtKB/TrEMBL
NCBI Gene Osgin2 ENTREZGENE
PANTHER OXIDATIVE STRESS-INDUCED GROWTH INHIBITOR 2 UniProtKB/TrEMBL
  PROTEIN CBG05349 UniProtKB/TrEMBL
Superfamily-SCOP FAD/NAD(P)-binding domain UniProtKB/TrEMBL
UniProt G5BBN8 ENTREZGENE, UniProtKB/TrEMBL