Ptpn12 (protein tyrosine phosphatase non-receptor type 12) - Rat Genome Database

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Gene: Ptpn12 (protein tyrosine phosphatase non-receptor type 12) Heterocephalus glaber
Analyze
Symbol: Ptpn12
Name: protein tyrosine phosphatase non-receptor type 12
RGD ID: 18909455
Description: ENCODES a protein that exhibits phosphoprotein phosphatase activity (ortholog); protein tyrosine phosphatase activity (ortholog); SH3 domain binding (ortholog); INVOLVED IN tissue regeneration (ortholog); ASSOCIATED WITH Chromosome 7q11.23 Deletion Syndrome, Distal, 1.2-MB (ortholog); colon carcinoma (ortholog); colorectal cancer (ortholog); FOUND IN cytosol (ortholog); podosome (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tyrosine-protein phosphatase non-receptor type 12
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473926,747,830 - 26,828,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ptpn12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473926,747,830 - 26,828,535 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PTPN12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38777,537,295 - 77,640,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl777,537,295 - 77,640,069 (+)EnsemblGRCh38hg38GRCh38
GRCh37777,166,612 - 77,269,386 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36777,004,771 - 77,107,322 (+)NCBINCBI36Build 36hg18NCBI36
Build 34776,811,485 - 76,914,037NCBI
Celera771,867,421 - 71,970,039 (+)NCBICelera
Cytogenetic Map7q11.23NCBI
HuRef771,768,818 - 71,871,494 (+)NCBIHuRef
CHM1_1777,097,083 - 77,199,758 (+)NCBICHM1_1
T2T-CHM13v2.0778,789,201 - 78,891,996 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2776,499,836 - 76,602,451 (+)NCBI
Ptpn12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39521,191,643 - 21,261,009 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl521,191,643 - 21,260,909 (-)EnsemblGRCm39 Ensembl
GRCm38520,986,645 - 21,055,911 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl520,986,645 - 21,055,911 (-)EnsemblGRCm38mm10GRCm38
MGSCv37520,492,463 - 20,561,615 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36520,498,469 - 20,567,621 (-)NCBIMGSCv36mm8
Celera517,944,646 - 18,014,696 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map59.83NCBI
Ptpn12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8414,913,071 - 14,985,084 (+)NCBIGRCr8
mRatBN7.2414,020,997 - 14,092,931 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl414,021,052 - 14,092,927 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx419,158,307 - 19,230,084 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0414,960,328 - 15,032,112 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0413,343,956 - 13,415,737 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0410,631,129 - 10,702,390 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl410,631,073 - 10,702,386 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0410,623,632 - 10,695,128 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.449,517,642 - 9,589,954 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.149,517,585 - 9,574,832 (+)NCBI
Celera49,582,368 - 9,654,126 (+)NCBICelera
Cytogenetic Map4q11NCBI
Ptpn12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554107,557,103 - 7,599,139 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554107,556,283 - 7,599,170 (-)NCBIChiLan1.0ChiLan1.0
PTPN12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2695,387,345 - 95,490,209 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17143,651,984 - 143,754,849 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0769,457,158 - 69,560,111 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1783,268,834 - 83,371,120 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl783,268,834 - 83,371,120 (+)Ensemblpanpan1.1panPan2
PTPN12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11817,608,665 - 17,692,543 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1817,607,936 - 17,692,219 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1817,266,233 - 17,315,593 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01817,927,205 - 18,011,994 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1817,927,265 - 18,011,993 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11817,677,847 - 17,762,567 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01817,617,247 - 17,702,020 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01817,886,436 - 17,971,250 (+)NCBIUU_Cfam_GSD_1.0
Ptpn12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511859,785,782 - 59,892,793 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647920,909,551 - 21,016,606 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647920,909,557 - 21,016,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTPN12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9102,480,924 - 102,563,751 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19102,480,914 - 102,563,969 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29112,920,939 - 112,961,308 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PTPN12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12171,285,917 - 71,389,645 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2171,285,736 - 71,389,926 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604232,533,869 - 32,637,803 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004839736   ⟹   XP_004839793
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473926,747,830 - 26,828,535 (+)NCBI
RefSeq Acc Id: XM_004839737   ⟹   XP_004839794
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473926,747,830 - 26,828,535 (+)NCBI
RefSeq Acc Id: XM_021253963   ⟹   XP_021109622
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473926,748,818 - 26,828,535 (+)NCBI
RefSeq Acc Id: XM_021253964   ⟹   XP_021109623
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473926,748,818 - 26,828,535 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004839793 (Get FASTA)   NCBI Sequence Viewer  
  XP_004839794 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109622 (Get FASTA)   NCBI Sequence Viewer  
  XP_021109623 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008318
Reference Protein Sequences
RefSeq Acc Id: XP_004839793   ⟸   XM_004839736
- Peptide Label: isoform X3
- UniProtKB: G5AJU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839794   ⟸   XM_004839737
- Peptide Label: isoform X4
- UniProtKB: G5AJU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109622   ⟸   XM_021253963
- Peptide Label: isoform X1
- UniProtKB: G5AJU8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109623   ⟸   XM_021253964
- Peptide Label: isoform X2
- UniProtKB: G5AJU8 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006021 ENTREZGENE
Ensembl Transcript ENSHGLT00000008407 ENTREZGENE
Gene3D-CATH Protein tyrosine phosphatase superfamily UniProtKB/TrEMBL
InterPro Prot-tyrosine_phosphatase-like UniProtKB/TrEMBL
  PTN12 UniProtKB/TrEMBL
  PTN12/18/22 UniProtKB/TrEMBL
  PTP_cat UniProtKB/TrEMBL
  Tyr_Pase_AS UniProtKB/TrEMBL
  Tyr_Pase_cat UniProtKB/TrEMBL
  Tyr_Pase_dom UniProtKB/TrEMBL
NCBI Gene Ptpn12 ENTREZGENE
PANTHER TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 12 UniProtKB/TrEMBL
Pfam Y_phosphatase UniProtKB/TrEMBL
PIRSF Tyr-Ptase_nr12 UniProtKB/TrEMBL
PRINTS PRTYPHPHTASE UniProtKB/TrEMBL
PROSITE TYR_PHOSPHATASE_1 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_2 UniProtKB/TrEMBL
  TYR_PHOSPHATASE_PTP UniProtKB/TrEMBL
SMART PTPc UniProtKB/TrEMBL
  PTPc_motif UniProtKB/TrEMBL
Superfamily-SCOP (Phosphotyrosine protein) phosphatases II UniProtKB/TrEMBL
UniProt G5AJU8 ENTREZGENE, UniProtKB/TrEMBL