Shroom4 (shroom family member 4) - Rat Genome Database

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Gene: Shroom4 (shroom family member 4) Heterocephalus glaber
Analyze
Symbol: Shroom4
Name: shroom family member 4
RGD ID: 18909371
Description: ENCODES a protein that exhibits myosin II binding (ortholog); INVOLVED IN actin filament organization (ortholog); brain development (ortholog); cell morphogenesis (ortholog); ASSOCIATED WITH autistic disorder (ortholog); congenital disorder of glycosylation type IIm (ortholog); genetic disease (ortholog); FOUND IN actin cytoskeleton (ortholog); actin filament (ortholog); basal plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Protein Shroom4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248932,373,815 - 2,660,199 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248932,373,847 - 2,660,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Shroom4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248932,373,815 - 2,660,199 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248932,373,847 - 2,660,122 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SHROOM4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X50,575,534 - 50,814,194 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX50,586,796 - 50,814,302 (-)EnsemblGRCh38hg38GRCh38
GRCh37X50,329,796 - 50,557,194 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X50,351,387 - 50,573,784 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX54,378,231 - 54,600,597 (-)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX47,778,364 - 48,000,648 (-)NCBIHuRef
CHM1_1X50,414,359 - 50,636,708 (-)NCBICHM1_1
T2T-CHM13v2.0X49,846,979 - 50,085,560 (-)NCBIT2T-CHM13v2.0
Shroom4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X6,312,012 - 6,549,508 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX6,311,908 - 6,549,502 (+)EnsemblGRCm39 Ensembl
GRCm38X6,399,949 - 6,637,454 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX6,399,854 - 6,637,448 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X5,977,263 - 6,210,835 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X5,575,508 - 5,812,930 (+)NCBIMGSCv36mm8
CeleraX4,778,748 - 5,011,260 (-)NCBICelera
Cytogenetic MapXA1.1NCBI
cM MapX2.85NCBI
Shroom4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X18,537,371 - 18,748,665 (-)NCBIGRCr8
mRatBN7.2X15,869,065 - 16,076,850 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX15,869,065 - 16,076,869 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX20,679,710 - 20,887,970 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X19,195,300 - 19,403,570 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X15,460,250 - 15,668,526 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X16,723,360 - 16,929,829 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX16,719,803 - 16,929,907 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X17,500,772 - 17,711,666 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X29,125,307 - 29,334,579 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
CeleraX15,939,398 - 16,146,959 (-)NCBICelera
Cytogenetic MapXq12NCBI
Shroom4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049555431,810,125 - 2,046,144 (-)NCBIChiLan1.0ChiLan1.0
SHROOM4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X51,940,087 - 52,188,702 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X51,945,765 - 52,192,297 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X42,673,968 - 42,974,947 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X50,464,617 - 50,568,075 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX50,464,824 - 50,687,221 (-)Ensemblpanpan1.1panPan2
SHROOM4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X43,366,921 - 43,639,525 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX43,369,472 - 43,639,302 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX17,743,343 - 18,016,771 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X43,486,469 - 43,759,942 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX43,487,462 - 43,760,464 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X43,490,284 - 43,763,685 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X43,478,265 - 43,751,712 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X43,573,217 - 43,846,683 (-)NCBIUU_Cfam_GSD_1.0
Shroom4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X35,828,330 - 36,037,677 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049367212,068,731 - 2,166,537 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SHROOM4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX44,332,620 - 44,543,337 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X44,301,956 - 44,543,969 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X49,298,058 - 49,474,957 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SHROOM4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X47,392,156 - 47,618,816 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX47,397,570 - 47,616,973 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666086984,033 - 1,212,187 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021249971 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021249972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01100432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100435 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100437 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100439 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100440 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100441 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01100449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH167494 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000004555   ⟹   ENSHGLP00000004493
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248932,373,815 - 2,660,199 (-)Ensembl
RefSeq Acc Id: XM_021249971   ⟹   XP_021105630
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248932,373,847 - 2,660,122 (-)NCBI
RefSeq Acc Id: XM_021249972   ⟹   XP_021105631
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248932,373,848 - 2,429,769 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021105630 (Get FASTA)   NCBI Sequence Viewer  
  XP_021105631 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01976 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000004493
Reference Protein Sequences
RefSeq Acc Id: XP_021105630   ⟸   XM_021249971
- Peptide Label: isoform X1
- UniProtKB: G5AY65 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021105631   ⟸   XM_021249972
- Peptide Label: isoform X2
- UniProtKB: G5AY65 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000004493   ⟸   ENSHGLT00000004555


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003286 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000004555 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  6.10.250.3120 UniProtKB/TrEMBL
InterPro ASD2_dom UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  Shroom_fam UniProtKB/TrEMBL
NCBI Gene Shroom4 ENTREZGENE
PANTHER APICAL PROTEIN/SHROOM-RELATED UniProtKB/TrEMBL
  PROTEIN SHROOM4 UniProtKB/TrEMBL
Pfam ASD2 UniProtKB/TrEMBL
PROSITE ASD2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
Superfamily-SCOP PDZ domain-like UniProtKB/TrEMBL
UniProt G5AY65 ENTREZGENE, UniProtKB/TrEMBL