Tbl3 (transducin beta like 3) - Rat Genome Database

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Gene: Tbl3 (transducin beta like 3) Heterocephalus glaber
Analyze
Symbol: Tbl3
Name: transducin beta like 3
RGD ID: 18908865
Description: ENCODES a protein that exhibits U3 snoRNA binding (inferred); INVOLVED IN endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (inferred); endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (inferred); ribosomal small subunit biogenesis (inferred); ASSOCIATED WITH epilepsy (ortholog); genetic disease (ortholog); idiopathic generalized epilepsy (ortholog); FOUND IN 90S preribosome (inferred); nucleolus (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: transducin beta-like protein 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913282,887 - 289,407 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913282,883 - 289,523 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Tbl3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624913282,887 - 289,407 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624913282,883 - 289,523 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TBL3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38161,972,053 - 1,982,929 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl161,972,053 - 1,982,929 (+)EnsemblGRCh38hg38GRCh38
GRCh37162,022,054 - 2,032,930 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36161,962,065 - 1,968,752 (+)NCBINCBI36Build 36hg18NCBI36
Build 34161,962,064 - 1,968,752NCBI
Celera162,234,243 - 2,240,930 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef161,946,130 - 1,952,817 (+)NCBIHuRef
CHM1_1162,021,993 - 2,028,680 (+)NCBICHM1_1
T2T-CHM13v2.0161,992,012 - 2,002,867 (+)NCBIT2T-CHM13v2.0
Tbl3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,919,627 - 24,926,627 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1724,916,923 - 24,926,634 (-)EnsemblGRCm39 Ensembl
GRCm381724,700,653 - 24,707,653 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,697,949 - 24,707,660 (-)EnsemblGRCm38mm10GRCm38
MGSCv371724,837,598 - 24,844,598 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361724,428,253 - 24,435,253 (-)NCBIMGSCv36mm8
Celera1725,223,575 - 25,230,579 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1712.49NCBI
Tbl3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81014,230,660 - 14,235,873 (-)NCBIGRCr8
mRatBN7.21013,726,127 - 13,731,340 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1013,726,129 - 13,731,372 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1018,472,824 - 18,478,043 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01017,961,677 - 17,966,896 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01013,460,879 - 13,466,098 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01014,066,984 - 14,072,197 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1014,066,948 - 14,072,230 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,883,207 - 13,888,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,953,946 - 13,959,159 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11013,953,945 - 13,959,159 (-)NCBI
Celera1013,405,868 - 13,411,081 (-)NCBICelera
Cytogenetic Map10q12NCBI
Tbl3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544215,290,759 - 15,297,442 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544215,290,759 - 15,297,070 (-)NCBIChiLan1.0ChiLan1.0
TBL3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2182,365,658 - 2,377,209 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1166,150,383 - 6,159,150 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v016725,629 - 732,350 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1162,061,074 - 2,067,974 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl162,061,199 - 2,067,715 (+)Ensemblpanpan1.1panPan2
TBL3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1638,956,227 - 38,962,189 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl638,788,454 - 38,962,167 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha640,195,917 - 40,201,875 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0639,273,245 - 39,279,203 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl639,273,245 - 39,279,193 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1638,950,022 - 38,955,978 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0638,922,328 - 38,928,286 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0639,401,215 - 39,407,173 (-)NCBIUU_Cfam_GSD_1.0
Tbl3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344104,642,890 - 104,649,243 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366942,060,220 - 2,066,575 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366942,060,218 - 2,066,525 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TBL3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl339,989,740 - 39,995,123 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1339,989,739 - 39,996,138 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TBL3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.151,867,943 - 1,874,640 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl51,867,917 - 1,875,236 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606829,193,058 - 29,199,944 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000003338   ⟹   ENSHGLP00000003283
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_004624913282,887 - 289,407 (-)Ensembl
RefSeq Acc Id: XM_004873675   ⟹   XP_004873732
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624913282,883 - 289,520 (-)NCBI
RefSeq Acc Id: XM_021251436   ⟹   XP_021107095
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_004624913282,883 - 289,523 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004873732 (Get FASTA)   NCBI Sequence Viewer  
  XP_021107095 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB14216 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000003283
  ENSHGLP00100017461
GenBank Protein JAN97313 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021107095   ⟸   XM_021251436
- Peptide Label: isoform X2
- UniProtKB: G5BY55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004873732   ⟸   XM_004873675
- Peptide Label: isoform X1
- UniProtKB: A0A0P6K1T9 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000003283   ⟸   ENSHGLT00000003338


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000002431 Ensembl, ENTREZGENE
  ENSHGLG00100012878 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000003338 ENTREZGENE
  ENSHGLT00100017646 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  SSU_processome_Utp13 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101722099 UniProtKB/TrEMBL
NCBI Gene Tbl3 ENTREZGENE
PANTHER TRANSDUCIN BETA-LIKE 3 UniProtKB/TrEMBL
  TRANSDUCIN BETA-LIKE PROTEIN 3 UniProtKB/TrEMBL
Pfam Utp13 UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/TrEMBL
UniProt A0A0P6K1T9 ENTREZGENE, UniProtKB/TrEMBL
  G5BY55 ENTREZGENE, UniProtKB/TrEMBL