Agbl1 (AGBL carboxypeptidase 1) - Rat Genome Database

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Gene: Agbl1 (AGBL carboxypeptidase 1) Heterocephalus glaber
Analyze
Symbol: Agbl1
Name: AGBL carboxypeptidase 1 (Ensembl:ATP/GTP binding protein like 1)
RGD ID: 18908607
Description: ENCODES a protein that exhibits tubulin binding (ortholog); INVOLVED IN proteolysis (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); Corneal Dystrophy, Fuchs Endothelial, 8 (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ATP/GTP binding protein like 1; Cytosolic carboxypeptidase 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476813,470,674 - 14,239,465 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476813,470,809 - 14,325,563 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
proteolysis  (IEA)

Cellular Component
cytosol  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Agbl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476813,470,674 - 14,239,465 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476813,470,809 - 14,325,563 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AGBL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381586,079,620 - 87,031,476 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1586,079,871 - 87,049,169 (+)EnsemblGRCh38hg38GRCh38
GRCh371586,622,851 - 87,572,283 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361584,486,246 - 85,373,287 (+)NCBINCBI36Build 36hg18NCBI36
Celera1563,086,740 - 63,973,544 (+)NCBICelera
Cytogenetic Map15q25.3NCBI
HuRef1562,798,057 - 63,684,981 (+)NCBIHuRef
CHM1_11586,526,864 - 87,413,136 (+)NCBICHM1_1
T2T-CHM13v2.01583,834,387 - 84,785,395 (+)NCBIT2T-CHM13v2.0
Agbl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39775,879,311 - 76,774,446 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl775,879,635 - 76,774,446 (+)EnsemblGRCm39 Ensembl
GRCm38776,229,591 - 77,124,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl776,229,887 - 77,124,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv37783,465,022 - 84,031,140 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36776,284,575 - 76,573,636 (+)NCBIMGSCv36mm8
Celera773,765,804 - 74,340,195 (+)NCBICelera
Cytogenetic Map7D1NCBI
cM Map743.87NCBI
Agbl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81139,453,667 - 140,360,473 (+)NCBIGRCr8
mRatBN7.21130,043,914 - 130,950,739 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1130,043,970 - 130,951,638 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01137,798,862 - 138,711,126 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1137,799,185 - 138,711,126 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01138,789,634 - 139,710,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41131,756,893 - 131,944,875 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1122,147,459 - 123,040,161 (+)NCBICelera
Cytogenetic Map1q31NCBI
Agbl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541618,130,605 - 18,686,108 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541617,885,757 - 18,686,124 (-)NCBIChiLan1.0ChiLan1.0
AGBL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21675,629,121 - 76,224,884 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11579,333,797 - 79,929,696 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01564,774,408 - 65,603,628 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11583,986,366 - 84,938,359 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1584,048,348 - 84,938,150 (+)Ensemblpanpan1.1panPan2
AGBL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1349,639,425 - 50,331,421 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl349,639,304 - 50,331,227 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha352,415,838 - 53,000,674 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0350,198,066 - 50,781,019 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl350,060,828 - 50,751,728 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1349,692,597 - 50,306,456 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0349,929,690 - 50,515,701 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0350,269,103 - 50,854,979 (+)NCBIUU_Cfam_GSD_1.0
Agbl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640133,839,393 - 133,880,423 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648312,358,754 - 12,586,674 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648312,358,731 - 13,056,267 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AGBL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1192,722,847 - 193,534,417 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11192,725,367 - 193,534,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21214,550,551 - 214,964,434 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AGBL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1294,702,646 - 5,528,743 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl294,703,207 - 5,294,973 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605941,633,731 - 42,381,338 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021264792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021264793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01048143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048148 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048162 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048164 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048175 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01048182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01006320 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH169905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000008876   ⟹   ENSHGLP00000008781
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476813,470,674 - 14,239,465 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000008877   ⟹   ENSHGLP00000008782
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476813,470,674 - 14,239,465 (+)Ensembl
RefSeq Acc Id: XM_021264792   ⟹   XP_021120451
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476813,470,809 - 14,325,563 (+)NCBI
RefSeq Acc Id: XM_021264793   ⟹   XP_021120452
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476813,470,809 - 14,238,390 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021120451 (Get FASTA)   NCBI Sequence Viewer  
  XP_021120452 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07878 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000008782
GenBank Protein JAN97312 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021120451   ⟸   XM_021264792
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JAB1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021120452   ⟸   XM_021264793
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000008782   ⟸   ENSHGLT00000008877
RefSeq Acc Id: ENSHGLP00000008781   ⟸   ENSHGLT00000008876


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000006320 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000008877 ENTREZGENE
Gene3D-CATH 1.25.10.10 UniProtKB/TrEMBL
  2.60.40.3120 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  CBPC1/4 UniProtKB/TrEMBL
  Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
NCBI Gene Agbl1 ENTREZGENE
PANTHER CYTOSOLIC CARBOXYPEPTIDASE UniProtKB/TrEMBL
  CYTOSOLIC CARBOXYPEPTIDASE 4 UniProtKB/TrEMBL
Pfam Pepdidase_M14_N UniProtKB/TrEMBL
  Peptidase_M14 UniProtKB/TrEMBL
Superfamily-SCOP SSF48371 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A0P6JAB1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-10 Agbl1  AGBL carboxypeptidase 1  Agbl1  ATP/GTP binding protein like 1  Symbol and/or name change 5135510 APPROVED