Tmed2 (transmembrane p24 trafficking protein 2) - Rat Genome Database

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Gene: Tmed2 (transmembrane p24 trafficking protein 2) Heterocephalus glaber
Analyze
Symbol: Tmed2
Name: transmembrane p24 trafficking protein 2
RGD ID: 18908200
Description: ENCODES a protein that exhibits frizzled binding (ortholog); smoothened binding (ortholog); INVOLVED IN allantois development (ortholog); branching involved in labyrinthine layer morphogenesis (ortholog); chorion development (ortholog); ASSOCIATED WITH genetic disease (ortholog); Myocardial Ischemia (ortholog); FOUND IN COPI-coated vesicle (ortholog); Golgi apparatus (ortholog); zymogen granule membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Transmembrane emp24 domain-containing protein 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474723,389,262 - 23,399,955 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474723,389,262 - 23,399,962 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Tmed2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474723,389,262 - 23,399,955 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474723,389,262 - 23,399,962 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TMED2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812123,584,552 - 123,598,582 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12123,584,533 - 123,598,582 (+)EnsemblGRCh38hg38GRCh38
GRCh3712124,069,099 - 124,083,129 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612122,635,029 - 122,648,641 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412122,594,040 - 122,607,561NCBI
Celera12123,665,514 - 123,679,126 (+)NCBICelera
Cytogenetic Map12q24.31NCBI
HuRef12121,030,441 - 121,044,052 (+)NCBIHuRef
CHM1_112123,890,022 - 123,903,633 (+)NCBICHM1_1
T2T-CHM13v2.012123,583,417 - 123,597,447 (+)NCBIT2T-CHM13v2.0
Tmed2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395124,678,835 - 124,688,566 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5124,678,758 - 124,688,569 (+)EnsemblGRCm39 Ensembl
GRCm385124,540,791 - 124,550,503 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5124,540,695 - 124,550,506 (+)EnsemblGRCm38mm10GRCm38
MGSCv375124,990,800 - 125,000,512 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365124,801,409 - 124,811,121 (+)NCBIMGSCv36mm8
Celera5121,616,969 - 121,626,684 (+)NCBICelera
Cytogenetic Map5FNCBI
cM Map563.65NCBI
Tmed2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81237,713,522 - 37,722,606 (-)NCBIGRCr8
mRatBN7.21232,052,542 - 32,061,628 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1232,052,543 - 32,071,903 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1233,231,743 - 33,240,850 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01233,843,066 - 33,852,174 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01232,894,932 - 32,904,047 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01237,471,259 - 37,480,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1237,471,260 - 37,480,297 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01239,342,087 - 39,351,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,165,291 - 33,174,326 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11233,028,678 - 33,037,714 (-)NCBI
Celera1233,742,602 - 33,751,640 (-)NCBICelera
Cytogenetic Map12q15NCBI
Tmed2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554825,404,739 - 5,415,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554825,404,739 - 5,415,243 (-)NCBIChiLan1.0ChiLan1.0
TMED2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210131,656,040 - 131,673,075 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112131,655,269 - 131,669,897 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012121,169,915 - 121,183,524 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112125,397,391 - 125,410,799 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12125,397,391 - 125,410,794 (+)Ensemblpanpan1.1panPan2
TMED2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1266,039,046 - 6,047,490 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl266,039,405 - 6,047,459 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha266,200,941 - 6,210,349 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0266,288,140 - 6,297,554 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl266,287,725 - 6,297,549 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,221,613 - 6,231,022 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0266,314,000 - 6,323,406 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0266,267,212 - 6,276,621 (-)NCBIUU_Cfam_GSD_1.0
Tmed2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118158,247,895 - 158,256,138 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365581,223,114 - 1,231,479 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365581,223,114 - 1,258,699 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMED2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1429,390,335 - 29,400,440 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11429,390,903 - 29,400,454 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21431,082,626 - 31,092,755 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TMED2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111118,913,145 - 118,927,335 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11118,913,078 - 118,928,281 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037126,348,858 - 126,363,072 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000027607   ⟹   ENSHGLP00000027365
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474723,389,262 - 23,399,955 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000027608   ⟹   ENSHGLP00000027366
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474723,389,342 - 23,398,598 (+)Ensembl
RefSeq Acc Id: XM_004843955   ⟹   XP_004844012
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474723,389,262 - 23,399,962 (+)NCBI
RefSeq Acc Id: XM_021257621   ⟹   XP_021113280
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474723,389,262 - 23,399,962 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004844012 (Get FASTA)   NCBI Sequence Viewer  
  XP_021113280 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB01481 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000027365
  ENSHGLP00000049679
  ENSHGLP00100002932
  ENSHGLP00100026310
GenBank Protein JAN96276 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021113280   ⟸   XM_021257621
- Peptide Label: isoform X1
- UniProtKB: G5BJI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004844012   ⟸   XM_004843955
- Peptide Label: isoform X2
- UniProtKB: G5AWT5 (UniProtKB/TrEMBL),   G5BJI3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000027365   ⟸   ENSHGLT00000027607
RefSeq Acc Id: ENSHGLP00000027366   ⟸   ENSHGLT00000027608


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019458 Ensembl, ENTREZGENE
  ENSHGLG00000020012 UniProtKB/TrEMBL
  ENSHGLG00100002257 UniProtKB/TrEMBL
  ENSHGLG00100019302 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000027607 ENTREZGENE
  ENSHGLT00000028222 UniProtKB/TrEMBL
  ENSHGLT00100002987 UniProtKB/TrEMBL
  ENSHGLT00100026578 UniProtKB/TrEMBL
InterPro Emp24-like UniProtKB/TrEMBL
  GOLD_dom UniProtKB/TrEMBL
  GOLD_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101698066 UniProtKB/TrEMBL
NCBI Gene Tmed2 ENTREZGENE
PANTHER PTHR22811 UniProtKB/TrEMBL
  TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam EMP24_GP25L UniProtKB/TrEMBL
PROSITE GOLD UniProtKB/TrEMBL
SMART EMP24_GP25L UniProtKB/TrEMBL
Superfamily-SCOP SSF101576 UniProtKB/TrEMBL
UniProt G5AWT5 ENTREZGENE, UniProtKB/TrEMBL
  G5BJI3 ENTREZGENE, UniProtKB/TrEMBL