Cacna2d1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Cacna2d1 (calcium voltage-gated channel auxiliary subunit alpha2delta 1) Heterocephalus glaber
Analyze
Symbol: Cacna2d1
Name: calcium voltage-gated channel auxiliary subunit alpha2delta 1
RGD ID: 18907596
Description: ENCODES a protein that exhibits voltage-gated calcium channel activity (ortholog); voltage-gated calcium channel activity involved in bundle of His cell action potential (ortholog); INVOLVED IN calcium ion transmembrane transport via high voltage-gated calcium channel (ortholog); calcium ion transport (ortholog); calcium ion transport into cytosol (ortholog); ASSOCIATED WITH brain infarction (ortholog); breast carcinoma (ortholog); Brugada syndrome (ortholog); FOUND IN GABA-ergic synapse (ortholog); glutamatergic synapse (ortholog); neuronal dense core vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: voltage-dependent calcium channel subunit alpha-2/delta-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473930,436,568 - 30,864,468 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473930,436,662 - 30,864,482 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Cacna2d1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473930,436,568 - 30,864,468 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473930,436,662 - 30,864,482 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CACNA2D1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38781,946,444 - 82,443,956 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl781,946,444 - 82,443,956 (-)EnsemblGRCh38hg38GRCh38
GRCh37781,575,760 - 82,073,272 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,417,354 - 81,910,967 (-)NCBINCBI36Build 36hg18NCBI36
Build 34781,224,068 - 81,717,682NCBI
Celera776,279,569 - 76,773,517 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef776,182,274 - 76,676,613 (-)NCBIHuRef
CHM1_1781,509,503 - 82,003,079 (-)NCBICHM1_1
T2T-CHM13v2.0783,197,632 - 83,695,210 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2780,910,288 - 81,405,123 (-)NCBI
Cacna2d1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39516,139,390 - 16,579,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl516,139,786 - 16,579,502 (+)EnsemblGRCm39 Ensembl
GRCm38515,934,264 - 16,374,511 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl515,934,691 - 16,374,511 (+)EnsemblGRCm38mm10GRCm38
MGSCv37515,440,509 - 15,880,329 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36515,446,612 - 15,882,875 (+)NCBIMGSCv36mm8
Celera512,936,968 - 13,372,202 (+)NCBICelera
Cytogenetic Map5A2- A3NCBI
cM Map56.56NCBI
Cacna2d1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8419,902,324 - 20,330,287 (-)NCBIGRCr8
mRatBN7.2418,950,611 - 19,374,969 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl418,951,002 - 19,374,969 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx424,107,697 - 24,535,090 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0419,924,586 - 20,351,968 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0418,305,637 - 18,733,033 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0415,706,974 - 16,130,848 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl415,710,417 - 16,130,848 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0415,681,399 - 16,105,483 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4415,139,881 - 15,566,740 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1415,169,848 - 15,566,733 (-)NCBI
Celera414,480,196 - 14,898,934 (-)NCBICelera
Cytogenetic Map4q12NCBI
Cacna2d1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554103,619,740 - 3,964,239 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554103,544,398 - 3,963,582 (+)NCBIChiLan1.0ChiLan1.0
CACNA2D1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2699,798,532 - 100,295,629 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17148,063,168 - 148,557,074 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0773,917,439 - 74,410,627 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1787,575,054 - 88,068,480 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl787,579,004 - 88,068,482 (-)Ensemblpanpan1.1panPan2
CACNA2D1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11821,561,091 - 21,949,970 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1821,564,676 - 21,949,544 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1821,233,630 - 21,714,674 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01822,009,947 - 22,485,359 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1822,009,954 - 22,485,691 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11821,646,522 - 22,121,006 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01821,182,147 - 21,656,514 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01821,836,185 - 22,311,929 (-)NCBIUU_Cfam_GSD_1.0
Cacna2d1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511863,375,924 - 63,825,676 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936734581,538 - 1,027,018 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936734577,656 - 1,027,412 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CACNA2D1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl997,781,090 - 98,266,969 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1997,781,057 - 98,265,925 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29108,068,038 - 108,554,997 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CACNA2D1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12166,449,154 - 66,937,643 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2166,770,578 - 66,934,898 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604237,008,715 - 37,508,631 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013280   ⟹   ENSHGLP00000013142
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473930,436,568 - 30,864,468 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000013281   ⟹   ENSHGLP00000013143
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473930,436,568 - 30,864,468 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000013282   ⟹   ENSHGLP00000013144
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473930,440,612 - 30,864,345 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000013283   ⟹   ENSHGLP00000013145
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473930,440,612 - 30,644,045 (-)Ensembl
RefSeq Acc Id: XM_004839765   ⟹   XP_004839822
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,436,662 - 30,864,481 (-)NCBI
RefSeq Acc Id: XM_013070349   ⟹   XP_012925803
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,436,662 - 30,864,481 (-)NCBI
RefSeq Acc Id: XM_013070350   ⟹   XP_012925804
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,436,662 - 30,864,481 (-)NCBI
RefSeq Acc Id: XM_013070351   ⟹   XP_012925805
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,436,662 - 30,864,481 (-)NCBI
RefSeq Acc Id: XM_013070352   ⟹   XP_012925806
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,445,335 - 30,864,482 (-)NCBI
RefSeq Acc Id: XM_021253994   ⟹   XP_021109653
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,436,662 - 30,864,482 (-)NCBI
RefSeq Acc Id: XM_021253995   ⟹   XP_021109654
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473930,448,398 - 30,864,482 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021109653   ⟸   XM_021253994
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925805   ⟸   XM_013070351
- Peptide Label: isoform X6
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925804   ⟸   XM_013070350
- Peptide Label: isoform X3
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004839822   ⟸   XM_004839765
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925803   ⟸   XM_013070349
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925806   ⟸   XM_013070352
- Peptide Label: isoform X7
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021109654   ⟸   XM_021253995
- Peptide Label: isoform X5
- UniProtKB: A0A0P6JVV8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000013143   ⟸   ENSHGLT00000013281
RefSeq Acc Id: ENSHGLP00000013145   ⟸   ENSHGLT00000013283
RefSeq Acc Id: ENSHGLP00000013144   ⟸   ENSHGLT00000013282
RefSeq Acc Id: ENSHGLP00000013142   ⟸   ENSHGLT00000013280


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009396 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000013280 ENTREZGENE
  ENSHGLT00000013281 ENTREZGENE
  ENSHGLT00000013282 ENTREZGENE
Gene3D-CATH 3.40.50.410 UniProtKB/TrEMBL
  PAS domain UniProtKB/TrEMBL
InterPro VDCC_a2/dsu UniProtKB/TrEMBL
  VWA_N UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene Cacna2d1 ENTREZGENE
PANTHER VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-1 UniProtKB/TrEMBL
  VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED UniProtKB/TrEMBL
Pfam VGCC_alpha2 UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
  VWA_N UniProtKB/TrEMBL
PROSITE VWFA UniProtKB/TrEMBL
SMART VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF53300 UniProtKB/TrEMBL
UniProt A0A0P6JVV8 ENTREZGENE, UniProtKB/TrEMBL