Prkg2 (protein kinase cGMP-dependent 2) - Rat Genome Database

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Gene: Prkg2 (protein kinase cGMP-dependent 2) Heterocephalus glaber
Analyze
Symbol: Prkg2
Name: protein kinase cGMP-dependent 2
RGD ID: 18907274
Description: ENCODES a protein that exhibits cGMP-dependent protein kinase activity (ortholog); identical protein binding (ortholog); mitogen-activated protein kinase binding (ortholog); INVOLVED IN cellular hypotonic response (ortholog); circadian regulation of gene expression (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH acromesomelic dysplasia-4 (ortholog); Dwarfism (ortholog); genetic disease (ortholog); FOUND IN nuclear membrane (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cGMP-dependent protein kinase 2; protein kinase, cGMP-dependent, type II
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247579,798,808 - 9,906,517 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247579,799,777 - 9,904,825 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Prkg2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247579,798,808 - 9,906,517 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247579,799,777 - 9,904,825 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PRKG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38481,087,370 - 81,217,836 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl481,087,370 - 81,215,222 (-)EnsemblGRCh38hg38GRCh38
GRCh37482,008,524 - 82,136,376 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36482,228,861 - 82,345,239 (-)NCBINCBI36Build 36hg18NCBI36
Build 34482,367,015 - 82,483,394NCBI
Celera479,302,549 - 79,418,932 (-)NCBICelera
Cytogenetic Map4q21.21NCBI
HuRef477,753,401 - 77,870,008 (-)NCBIHuRef
CHM1_1481,986,323 - 82,102,706 (-)NCBICHM1_1
T2T-CHM13v2.0484,417,063 - 84,547,534 (-)NCBIT2T-CHM13v2.0
Prkg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39599,077,632 - 99,185,042 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl599,077,632 - 99,185,210 (-)EnsemblGRCm39 Ensembl
GRCm38598,929,773 - 99,037,375 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl598,929,773 - 99,037,351 (-)EnsemblGRCm38mm10GRCm38
MGSCv37599,358,792 - 99,466,098 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36599,171,570 - 99,277,381 (-)NCBIMGSCv36mm8
Celera596,252,278 - 96,360,518 (-)NCBICelera
Cytogenetic Map5E3NCBI
cM Map548.35NCBI
Prkg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81410,864,020 - 10,972,617 (+)NCBIGRCr8
mRatBN7.21410,559,882 - 10,668,479 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1410,559,882 - 10,666,888 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1410,540,037 - 10,640,477 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01411,839,852 - 11,940,298 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01410,529,813 - 10,630,458 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01412,217,121 - 12,313,616 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1412,218,553 - 12,315,229 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01412,159,378 - 12,255,994 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41411,888,101 - 12,005,547 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11411,888,100 - 12,005,547 (+)NCBI
Celera1410,666,687 - 10,755,836 (+)NCBICelera
Cytogenetic Map14p22NCBI
Prkg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554335,286,153 - 5,491,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554335,286,594 - 5,387,571 (-)NCBIChiLan1.0ChiLan1.0
PRKG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2348,855,500 - 48,982,421 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1449,044,222 - 49,172,066 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0442,987,217 - 43,114,993 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1448,836,953 - 48,960,383 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl448,836,953 - 48,960,383 (+)Ensemblpanpan1.1panPan2
PRKG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1325,266,435 - 5,365,396 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl325,266,442 - 5,365,396 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3236,517,409 - 36,617,588 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0325,294,681 - 5,395,076 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl325,294,693 - 5,395,085 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1325,324,348 - 5,424,902 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0325,231,256 - 5,331,589 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03234,635,113 - 34,735,693 (+)NCBIUU_Cfam_GSD_1.0
Prkg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052856,966,547 - 7,070,004 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936749900,208 - 991,891 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PRKG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8136,755,469 - 136,852,906 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18136,754,698 - 136,854,589 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28146,048,858 - 146,148,011 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PRKG2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1729,511,796 - 29,629,943 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl729,511,380 - 29,618,330 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660378,011,684 - 8,129,346 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000010253   ⟹   ENSHGLP00000010139
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247579,798,808 - 9,906,517 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000010254   ⟹   ENSHGLP00000010140
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247579,800,335 - 9,903,732 (+)Ensembl
RefSeq Acc Id: XM_004847992   ⟹   XP_004848049
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247579,800,286 - 9,904,825 (+)NCBI
RefSeq Acc Id: XM_004847993   ⟹   XP_004848050
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247579,799,777 - 9,904,825 (+)NCBI
RefSeq Acc Id: XM_013073352   ⟹   XP_012928806
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247579,800,285 - 9,904,825 (+)NCBI
RefSeq Acc Id: XM_013073353   ⟹   XP_012928807
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247579,855,634 - 9,904,825 (+)NCBI
RefSeq Acc Id: XM_021260976   ⟹   XP_021116635
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247579,857,418 - 9,904,825 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004848050   ⟸   XM_004847993
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JAK9 (UniProtKB/TrEMBL),   G5AME9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012928806   ⟸   XM_013073352
- Peptide Label: isoform X2
- UniProtKB: G5AME9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004848049   ⟸   XM_004847992
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JAK9 (UniProtKB/TrEMBL),   G5AME9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012928807   ⟸   XM_013073353
- Peptide Label: isoform X3
RefSeq Acc Id: XP_021116635   ⟸   XM_021260976
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000010140   ⟸   ENSHGLT00000010254
RefSeq Acc Id: ENSHGLP00000010139   ⟸   ENSHGLT00000010253


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007272 Ensembl, ENTREZGENE
  ENSHGLG00100014125 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000010253 ENTREZGENE
  ENSHGLT00000010254 ENTREZGENE
  ENSHGLT00100091841 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/TrEMBL
  cGMP_dep_kinase UniProtKB/TrEMBL
  cNMP-bd-like UniProtKB/TrEMBL
  cNMP-bd_CS UniProtKB/TrEMBL
  cNMP-bd_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  RmlC-like_jellyroll UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
  STKc_cGK UniProtKB/TrEMBL
KEGG Report hgl:101697843 UniProtKB/TrEMBL
NCBI Gene Prkg2 ENTREZGENE
PANTHER CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE UniProtKB/TrEMBL
  PTHR24353:SF24 UniProtKB/TrEMBL
Pfam cNMP_binding UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
PIRSF cGMP-dep_kinase UniProtKB/TrEMBL
PRINTS CGMPKINASE UniProtKB/TrEMBL
PROSITE AGC_KINASE_CTER UniProtKB/TrEMBL
  CNMP_BINDING_1 UniProtKB/TrEMBL
  CNMP_BINDING_2 UniProtKB/TrEMBL
  CNMP_BINDING_3 UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART cNMP UniProtKB/TrEMBL
  S_TK_X UniProtKB/TrEMBL
  S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF51206 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A0P6JAK9 ENTREZGENE, UniProtKB/TrEMBL
  G5AME9 ENTREZGENE, UniProtKB/TrEMBL