Scpep1 (serine carboxypeptidase 1) - Rat Genome Database

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Gene: Scpep1 (serine carboxypeptidase 1) Heterocephalus glaber
Analyze
Symbol: Scpep1
Name: serine carboxypeptidase 1
RGD ID: 18907258
Description: ENCODES a protein that exhibits carboxypeptidase activity (inferred); serine-type carboxypeptidase activity (inferred); INVOLVED IN blood vessel diameter maintenance (ortholog); negative regulation of blood pressure (ortholog); retinoic acid metabolic process (ortholog); ASSOCIATED WITH COVID-19 (ortholog); genetic disease (ortholog); Joubert syndrome 1 (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Retinoid-inducible serine carboxypeptidase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479512,016,302 - 12,042,353 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479512,016,363 - 12,041,615 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Scpep1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479512,016,302 - 12,042,353 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479512,016,363 - 12,041,615 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SCPEP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381756,978,131 - 57,006,768 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1756,978,129 - 57,006,768 (+)EnsemblGRCh38hg38GRCh38
GRCh371755,055,492 - 55,084,129 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361752,410,467 - 52,439,128 (+)NCBINCBI36Build 36hg18NCBI36
Build 341752,410,487 - 52,439,123NCBI
Celera1751,517,044 - 51,545,707 (+)NCBICelera
Cytogenetic Map17q22NCBI
HuRef1750,416,496 - 50,445,158 (+)NCBIHuRef
CHM1_11755,120,690 - 55,149,356 (+)NCBICHM1_1
T2T-CHM13v2.01757,855,772 - 57,884,410 (+)NCBIT2T-CHM13v2.0
Scpep1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391188,814,846 - 88,846,268 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1188,814,846 - 88,846,291 (-)EnsemblGRCm39 Ensembl
GRCm381188,924,020 - 88,955,442 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1188,924,020 - 88,955,465 (-)EnsemblGRCm38mm10GRCm38
MGSCv371188,785,334 - 88,816,756 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361188,740,110 - 88,771,522 (-)NCBIMGSCv36mm8
Celera1198,535,098 - 98,568,204 (-)NCBICelera
Cytogenetic Map11CNCBI
cM Map1154.34NCBI
Scpep1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81074,200,491 - 74,230,107 (-)NCBIGRCr8
mRatBN7.21073,703,275 - 73,732,892 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1073,703,278 - 73,732,850 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1078,318,490 - 78,347,988 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01077,823,415 - 77,852,910 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01073,286,585 - 73,316,078 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01076,230,371 - 76,263,866 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1076,230,373 - 76,263,866 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01073,846,394 - 73,880,406 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41077,347,473 - 77,377,945 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11077,361,844 - 77,392,315 (-)NCBI
Celera1072,609,315 - 72,638,737 (-)NCBICelera
Cytogenetic Map10q26NCBI
Scpep1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554515,846,552 - 5,876,851 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554515,847,371 - 5,876,286 (-)NCBIChiLan1.0ChiLan1.0
SCPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21973,151,012 - 73,179,770 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11777,961,953 - 77,990,686 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01751,055,293 - 51,084,032 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11755,915,746 - 55,944,374 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1755,915,746 - 55,944,377 (+)Ensemblpanpan1.1panPan2
SCPEP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1931,770,494 - 31,803,741 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl931,774,602 - 31,803,741 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha931,010,418 - 31,043,464 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0932,578,347 - 32,611,364 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl932,578,396 - 32,611,601 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1931,363,955 - 31,397,132 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0931,647,649 - 31,680,837 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0931,731,073 - 31,764,270 (+)NCBIUU_Cfam_GSD_1.0
Scpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560231,143,599 - 31,171,166 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364905,904,396 - 5,939,915 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364905,903,884 - 5,939,953 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SCPEP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1233,265,562 - 33,298,142 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11233,265,509 - 33,296,805 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21233,995,016 - 34,027,373 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SCPEP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11636,398,059 - 36,427,429 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1636,398,615 - 36,427,404 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660777,216,719 - 7,246,075 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017546   ⟹   ENSHGLP00000017373
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479512,016,302 - 12,042,353 (+)Ensembl
RefSeq Acc Id: XM_004859801   ⟹   XP_004859858
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479512,016,363 - 12,041,615 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004859858 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16799 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017373
GenBank Protein JAO01827 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004859858   ⟸   XM_004859801
- UniProtKB: G5C5I8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000017373   ⟸   ENSHGLT00000017546


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012440 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000017546 ENTREZGENE
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Peptidase_S10 UniProtKB/TrEMBL
  Ser_caboxypep_ser_AS UniProtKB/TrEMBL
NCBI Gene Scpep1 ENTREZGENE
PANTHER PTHR11802 UniProtKB/TrEMBL
  RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE UniProtKB/TrEMBL
Pfam Peptidase_S10 UniProtKB/TrEMBL
PRINTS CRBOXYPTASEC UniProtKB/TrEMBL
PROSITE CARBOXYPEPT_SER_SER UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt G5C5I8 ENTREZGENE, UniProtKB/TrEMBL