Trdmt1 (tRNA aspartic acid methyltransferase 1) - Rat Genome Database

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Gene: Trdmt1 (tRNA aspartic acid methyltransferase 1) Heterocephalus glaber
Analyze
Symbol: Trdmt1
Name: tRNA aspartic acid methyltransferase 1
RGD ID: 18907114
Description: ENCODES a protein that exhibits tRNA (cytidine-5-)-methyltransferase activity (ortholog); tRNA methyltransferase activity (ortholog); INVOLVED IN response to amphetamine (ortholog); tRNA methylation (ortholog); tRNA stabilization (ortholog); ASSOCIATED WITH genetic disease (ortholog); hypoparathyroidism-deafness-renal disease syndrome (ortholog); Imerslund-Grasbeck Syndrome (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: tRNA (cytosine(38)-C(5))-methyltransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,656,432 - 10,710,124 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,630,982 - 10,712,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Trdmt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462479610,656,432 - 10,710,124 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462479610,630,982 - 10,712,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
TRDMT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381017,137,336 - 17,201,672 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1017,137,336 - 17,202,054 (-)EnsemblGRCh38hg38GRCh38
GRCh371017,179,335 - 17,243,671 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361017,224,988 - 17,283,687 (-)NCBINCBI36Build 36hg18NCBI36
Celera1017,118,228 - 17,177,333 (-)NCBICelera
Cytogenetic Map10p13NCBI
HuRef1017,098,163 - 17,157,293 (-)NCBIHuRef
CHM1_11017,185,114 - 17,244,194 (-)NCBICHM1_1
T2T-CHM13v2.01017,155,855 - 17,220,211 (-)NCBIT2T-CHM13v2.0
Trdmt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39213,509,690 - 13,549,475 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl213,513,825 - 13,549,479 (-)EnsemblGRCm39 Ensembl
GRCm38213,504,879 - 13,544,797 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl213,509,014 - 13,544,668 (-)EnsemblGRCm38mm10GRCm38
MGSCv37213,431,788 - 13,466,291 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36213,428,017 - 13,462,517 (-)NCBIMGSCv36mm8
Celera213,420,290 - 13,454,789 (-)NCBICelera
Cytogenetic Map2A1NCBI
cM Map210.0NCBI
Trdmt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81781,510,740 - 81,554,036 (-)NCBIGRCr8
mRatBN7.21776,601,966 - 76,646,104 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1776,610,543 - 76,645,439 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1780,085,168 - 80,118,000 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01783,920,574 - 83,953,406 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01777,968,474 - 78,001,306 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01780,824,652 - 80,859,585 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1780,826,846 - 80,860,195 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01782,445,133 - 82,478,017 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41787,791,647 - 87,824,484 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11787,802,488 - 87,835,316 (-)NCBI
Celera1775,981,585 - 76,014,443 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
Trdmt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542910,742,097 - 10,771,877 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542910,741,512 - 10,774,268 (+)NCBIChiLan1.0ChiLan1.0
TRDMT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2829,989,412 - 30,044,694 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11029,985,157 - 30,050,016 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01017,460,091 - 17,518,855 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11017,726,701 - 17,791,345 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1017,738,374 - 17,791,345 (-)Ensemblpanpan1.1panPan2
TRDMT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1219,702,561 - 19,763,744 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl219,677,444 - 19,763,741 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha216,806,079 - 16,867,665 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0219,994,579 - 20,056,169 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl219,999,196 - 20,057,521 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1217,196,915 - 17,258,530 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0218,035,155 - 18,097,023 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0218,653,004 - 18,714,640 (+)NCBIUU_Cfam_GSD_1.0
Trdmt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934417,839,758 - 17,856,427 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493652010,104,050 - 10,122,057 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRDMT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1043,434,444 - 43,493,892 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11043,434,148 - 43,494,924 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21048,148,992 - 48,157,057 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRDMT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1917,098,086 - 17,166,267 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl917,100,491 - 17,155,826 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605122,733,372 - 22,794,872 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000005790   ⟹   ENSHGLP00000005718
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462479610,656,432 - 10,710,124 (+)Ensembl
RefSeq Acc Id: XM_004859970   ⟹   XP_004860027
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,656,843 - 10,712,689 (+)NCBI
RefSeq Acc Id: XM_004859973   ⟹   XP_004860030
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,656,844 - 10,704,925 (+)NCBI
RefSeq Acc Id: XM_021240502   ⟹   XP_021096161
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,656,836 - 10,712,689 (+)NCBI
RefSeq Acc Id: XR_002387865
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,656,732 - 10,710,051 (+)NCBI
RefSeq Acc Id: XR_002387866
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,656,743 - 10,712,689 (+)NCBI
RefSeq Acc Id: XR_002387867
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,656,833 - 10,710,041 (+)NCBI
RefSeq Acc Id: XR_002387868
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,657,293 - 10,710,051 (+)NCBI
RefSeq Acc Id: XR_002387869
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,630,982 - 10,710,051 (+)NCBI
RefSeq Acc Id: XR_002387870
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462479610,677,984 - 10,710,051 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004860027 (Get FASTA)   NCBI Sequence Viewer  
  XP_004860030 (Get FASTA)   NCBI Sequence Viewer  
  XP_021096161 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005718
Reference Protein Sequences
RefSeq Acc Id: XP_021096161   ⟸   XM_021240502
- Peptide Label: isoform X2
- UniProtKB: G5BFE5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860027   ⟸   XM_004859970
- Peptide Label: isoform X1
- UniProtKB: G5BFE5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004860030   ⟸   XM_004859973
- Peptide Label: isoform X3
RefSeq Acc Id: ENSHGLP00000005718   ⟸   ENSHGLT00000005790


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000004178 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005790 ENTREZGENE
Gene3D-CATH DNA Methylase, subunit A, domain 2 UniProtKB/TrEMBL
  Vaccinia Virus protein VP39 UniProtKB/TrEMBL
InterPro C5_MeTfrase UniProtKB/TrEMBL
  C5_meth_CS UniProtKB/TrEMBL
  SAM-dependent_MTases_sf UniProtKB/TrEMBL
NCBI Gene Trdmt1 ENTREZGENE
PANTHER TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE UniProtKB/TrEMBL
  TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE UniProtKB/TrEMBL
Pfam DNA_methylase UniProtKB/TrEMBL
PRINTS C5METTRFRASE UniProtKB/TrEMBL
PROSITE C5_MTASE_2 UniProtKB/TrEMBL
  SAM_MT_C5 UniProtKB/TrEMBL
Superfamily-SCOP S-adenosyl-L-methionine-dependent methyltransferases UniProtKB/TrEMBL
UniProt G5BFE5 ENTREZGENE, UniProtKB/TrEMBL