Hmox2 (heme oxygenase 2) - Rat Genome Database

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Gene: Hmox2 (heme oxygenase 2) Heterocephalus glaber
Analyze
Symbol: Hmox2
Name: heme oxygenase 2
RGD ID: 18907057
Description: ENCODES a protein that exhibits heme oxygenase (decyclizing) activity (ortholog); INVOLVED IN response to hypoxia (ortholog); response to oxidative stress (ortholog); ASSOCIATED WITH Cerebral Hemorrhage (ortholog); epilepsy (ortholog); genetic disease (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: heme oxygenase (decycling) 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248242,272,515 - 2,317,115 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Hmox2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248242,272,515 - 2,317,115 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HMOX2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38164,474,736 - 4,510,347 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl164,474,690 - 4,510,347 (+)EnsemblGRCh38hg38GRCh38
GRCh37164,524,737 - 4,560,348 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36164,466,447 - 4,500,349 (+)NCBINCBI36Build 36hg18NCBI36
Build 34164,466,446 - 4,500,348NCBI
Celera164,733,625 - 4,769,241 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef164,492,031 - 4,527,516 (+)NCBIHuRef
CHM1_1164,524,657 - 4,560,277 (+)NCBICHM1_1
T2T-CHM13v2.0164,504,257 - 4,539,822 (+)NCBIT2T-CHM13v2.0
Hmox2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39164,544,225 - 4,584,606 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl164,544,225 - 4,584,606 (+)EnsemblGRCm39 Ensembl
GRCm38164,726,361 - 4,766,742 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl164,726,361 - 4,766,742 (+)EnsemblGRCm38mm10GRCm38
MGSCv37164,726,361 - 4,766,249 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36164,656,841 - 4,681,476 (+)NCBIMGSCv36mm8
Celera165,357,042 - 5,398,127 (+)NCBICelera
Cytogenetic Map16A1NCBI
cM Map162.46NCBI
Hmox2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81011,303,512 - 11,337,640 (-)NCBIGRCr8
mRatBN7.21010,797,076 - 10,831,178 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1010,797,055 - 10,831,148 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1015,505,604 - 15,539,849 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01014,994,426 - 15,028,671 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01010,663,877 - 10,698,152 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01010,990,034 - 11,035,493 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1010,990,034 - 11,035,484 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0109,756,647 - 9,800,842 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41010,914,157 - 10,929,448 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11010,914,156 - 10,929,448 (-)NCBI
Celera109,760,483 - 9,793,519 (-)NCBICelera
Cytogenetic Map10q12NCBI
Hmox2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544212,913,983 - 12,920,152 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544212,913,983 - 12,947,412 (-)NCBIChiLan1.0ChiLan1.0
HMOX2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2185,004,553 - 5,040,043 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1168,794,278 - 8,830,538 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0163,399,715 - 3,436,018 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1164,567,825 - 4,604,596 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl164,567,828 - 4,604,596 (+)Ensemblpanpan1.1panPan2
HMOX2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1636,881,073 - 36,898,062 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl636,881,506 - 36,898,042 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha638,209,606 - 38,240,992 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0637,085,031 - 37,117,118 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl637,085,038 - 37,117,547 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1636,879,455 - 36,911,205 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0636,772,360 - 36,804,385 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0637,174,250 - 37,205,632 (-)NCBIUU_Cfam_GSD_1.0
Hmox2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344106,695,873 - 106,712,812 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365304,556,706 - 4,557,663 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365304,556,617 - 4,558,250 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HMOX2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl337,831,439 - 37,868,128 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1337,829,044 - 37,868,163 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2338,887,097 - 38,923,044 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HMOX2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.154,157,402 - 4,201,223 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366606826,486,456 - 26,522,635 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004864783   ⟹   XP_004864840
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248242,290,270 - 2,317,115 (+)NCBI
RefSeq Acc Id: XM_004864784   ⟹   XP_004864841
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248242,272,515 - 2,317,115 (+)NCBI
RefSeq Acc Id: XM_004864785   ⟹   XP_004864842
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248242,272,519 - 2,317,115 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004864840 (Get FASTA)   NCBI Sequence Viewer  
  XP_004864841 (Get FASTA)   NCBI Sequence Viewer  
  XP_004864842 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB15057 (Get FASTA)   NCBI Sequence Viewer  
  JAN99224 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004864841   ⟸   XM_004864784
- UniProtKB: G5C0J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004864842   ⟸   XM_004864785
- UniProtKB: G5C0J6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004864840   ⟸   XM_004864783
- UniProtKB: G5C0J6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Gene3D-CATH 1.20.910.10 UniProtKB/TrEMBL
InterPro Haem_Oase UniProtKB/TrEMBL
  Haem_Oase-like UniProtKB/TrEMBL
  Haem_Oase-like_multi-hlx UniProtKB/TrEMBL
  Haem_oxygenase_CS UniProtKB/TrEMBL
KEGG Report hgl:101718879 UniProtKB/TrEMBL
NCBI Gene Hmox2 ENTREZGENE
PANTHER HEME OXYGENASE 2 UniProtKB/TrEMBL
  PTHR10720 UniProtKB/TrEMBL
Pfam Heme_oxygenase UniProtKB/TrEMBL
PRINTS HAEMOXYGNASE UniProtKB/TrEMBL
PROSITE HEME_OXYGENASE UniProtKB/TrEMBL
Superfamily-SCOP SSF48613 UniProtKB/TrEMBL
UniProt G5C0J6 ENTREZGENE, UniProtKB/TrEMBL