Trpm6 (transient receptor potential cation channel subfamily M member 6) - Rat Genome Database

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Gene: Trpm6 (transient receptor potential cation channel subfamily M member 6) Heterocephalus glaber
Analyze
Symbol: Trpm6
Name: transient receptor potential cation channel subfamily M member 6
RGD ID: 18906973
Description: ENCODES a protein that exhibits calcium ion transmembrane transporter activity (ortholog); magnesium ion transmembrane transporter activity (ortholog); INVOLVED IN magnesium ion transmembrane transport (ortholog); metal ion transport (ortholog); response to toxic substance (ortholog); ASSOCIATED WITH cone-rod dystrophy (ortholog); Eye Abnormalities (ortholog); genetic disease (ortholog); FOUND IN brush border membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248112,345,698 - 2,465,385 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248112,342,084 - 2,494,601 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Trpm6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248112,345,698 - 2,465,385 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248112,342,084 - 2,494,601 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
TRPM6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38974,722,495 - 74,887,921 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl974,722,495 - 74,888,094 (-)Ensemblhg38GRCh38
GRCh37977,337,411 - 77,502,837 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36976,527,231 - 76,692,830 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34974,566,964 - 74,732,564NCBI
Celera947,911,447 - 48,077,035 (-)NCBICelera
Cytogenetic Map9q21.13NCBI
HuRef947,159,778 - 47,325,152 (-)NCBIHuRef
CHM1_1977,483,852 - 77,649,496 (-)NCBICHM1_1
T2T-CHM13v2.0986,875,552 - 87,041,025 (-)NCBIT2T-CHM13v2.0
Trpm6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391918,707,566 - 18,869,885 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1918,727,347 - 18,869,875 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381918,730,177 - 18,892,521 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1918,749,983 - 18,892,511 (+)Ensemblmm10GRCm38
MGSCv371918,824,473 - 18,967,001 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361918,817,002 - 18,959,534 (+)NCBIMGSCv36mm8
Celera1919,438,745 - 19,578,144 (+)NCBICelera
Cytogenetic Map19BNCBI
cM Map1913.21NCBI
Trpm6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81225,559,528 - 225,747,106 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1225,576,872 - 225,747,108 (+)EnsemblGRCr8
mRatBN7.21216,136,407 - 216,320,523 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1216,170,038 - 216,320,520 (+)EnsemblmRatBN7.2
Rnor_6.01234,478,908 - 234,631,264 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1234,479,289 - 234,596,971 (-)Ensemblrn6Rnor6.0
Rnor_5.01241,578,982 - 241,729,073 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41222,363,324 - 222,502,191 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1213,469,067 - 213,615,762 (+)NCBICelera
RGSC_v3.11222,493,769 - 222,666,592 (+)NCBI
Cytogenetic Map1q51NCBI
Trpm6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555124,179,651 - 4,321,902 (+)Ensembl
ChiLan1.0NW_0049555124,179,194 - 4,323,523 (+)NCBIChiLan1.0ChiLan1.0
TRPM6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21173,887,787 - 74,054,681 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1973,893,728 - 74,060,622 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0949,949,883 - 50,114,169 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1973,576,594 - 73,742,195 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl973,576,594 - 73,742,195 (-)EnsemblpanPan2panpan1.1
TRPM6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1183,250,870 - 83,437,044 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl183,308,788 - 83,436,644 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha183,772,476 - 83,901,214 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0183,758,383 - 83,891,749 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl183,740,158 - 83,887,142 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1183,486,316 - 83,642,749 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0183,204,818 - 83,361,350 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0183,989,135 - 84,122,089 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Trpm6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947130,536,862 - 130,665,571 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650310,508,989 - 10,616,972 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493650310,508,989 - 10,637,424 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRPM6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1227,811,204 - 227,963,309 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11227,809,511 - 228,037,923 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,708,592 - 254,863,990 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRPM6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11285,773,663 - 85,954,807 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1285,773,344 - 85,903,293 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603874,218,052 - 74,377,383 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trpm6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1218,760,619 - 18,901,122 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000005333   ⟹   ENSHGLP00000005264
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248112,345,698 - 2,465,385 (-)Ensembl
RefSeq Acc Id: XM_004862521   ⟹   XP_004862578
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,342,084 - 2,494,601 (-)NCBI
RefSeq Acc Id: XM_013078796   ⟹   XP_012934250
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,342,084 - 2,494,392 (-)NCBI
RefSeq Acc Id: XM_021242724   ⟹   XP_021098383
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,342,084 - 2,494,171 (-)NCBI
RefSeq Acc Id: XM_021242725   ⟹   XP_021098384
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,342,084 - 2,494,172 (-)NCBI
RefSeq Acc Id: XM_021242726   ⟹   XP_021098385
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,377,898 - 2,494,183 (-)NCBI
RefSeq Acc Id: XM_021242727   ⟹   XP_021098386
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,407,925 - 2,494,185 (-)NCBI
RefSeq Acc Id: XR_002388723
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248112,378,408 - 2,494,184 (-)NCBI
RefSeq Acc Id: XP_004862578   ⟸   XM_004862521
- Peptide Label: isoform X2
- UniProtKB: G5BHU0 (UniProtKB/TrEMBL),   A0AAX6PY28 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012934250   ⟸   XM_013078796
- Peptide Label: isoform X4
- UniProtKB: A0A0P6J5I7 (UniProtKB/TrEMBL),   G5BHU0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098384   ⟸   XM_021242725
- Peptide Label: isoform X3
- UniProtKB: G5BHU0 (UniProtKB/TrEMBL),   A0AAX6RQV0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098383   ⟸   XM_021242724
- Peptide Label: isoform X1
- UniProtKB: G5BHU0 (UniProtKB/TrEMBL),   A0AAX6RRH8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098385   ⟸   XM_021242726
- Peptide Label: isoform X5
- UniProtKB: G5BHU0 (UniProtKB/TrEMBL),   A0AAX6RMP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021098386   ⟸   XM_021242727
- Peptide Label: isoform X6
- UniProtKB: A0AAX6RNN0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000005264   ⟸   ENSHGLT00000005333


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003851 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000005333 ENTREZGENE
Gene3D-CATH 1.20.5.1010 UniProtKB/TrEMBL
  MHCK/EF2 kinase UniProtKB/TrEMBL
  Phosphorylase Kinase, domain 1 UniProtKB/TrEMBL
InterPro Ion_trans_dom UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MHCK_EF2_kinase UniProtKB/TrEMBL
  TRPM UniProtKB/TrEMBL
  TRPM-like UniProtKB/TrEMBL
  TRPM6 UniProtKB/TrEMBL
  TRPM_SLOG UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
  TRPM_tetra_sf UniProtKB/TrEMBL
KEGG Report hgl:101707911 UniProtKB/TrEMBL
NCBI Gene Trpm6 ENTREZGENE
PANTHER PTHR13800:SF15 UniProtKB/TrEMBL
  TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 UniProtKB/TrEMBL
Pfam Alpha_kinase UniProtKB/TrEMBL
  Ion_trans UniProtKB/TrEMBL
  LSDAT_euk UniProtKB/TrEMBL
  TRPM2 UniProtKB/TrEMBL
  TRPM_tetra UniProtKB/TrEMBL
PROSITE ALPHA_KINASE UniProtKB/TrEMBL
SMART Alpha_kinase UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A0P6J5I7 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PY28 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RMP3 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RNN0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RQV0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RRH8 ENTREZGENE, UniProtKB/TrEMBL
  G5BHU0 ENTREZGENE, UniProtKB/TrEMBL