Irf6 (interferon regulatory factor 6) - Rat Genome Database

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Gene: Irf6 (interferon regulatory factor 6) Heterocephalus glaber
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Symbol: Irf6
Name: interferon regulatory factor 6
RGD ID: 18906863
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); sequence-specific DNA binding (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cell development (ortholog); cell population proliferation (ortholog); cranial skeletal system development (ortholog); ASSOCIATED WITH cleft lip (ortholog); cleft palate (ortholog); Congenital Limb Deformities (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248072,193,798 - 2,206,768 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248072,190,721 - 2,207,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Irf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248072,193,798 - 2,206,768 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248072,190,721 - 2,207,183 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IRF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381209,785,617 - 209,806,142 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1209,785,617 - 209,806,175 (-)EnsemblGRCh38hg38GRCh38
GRCh371209,958,962 - 209,979,487 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361208,027,885 - 208,046,102 (-)NCBINCBI36Build 36hg18NCBI36
Build 341206,349,656 - 206,367,874NCBI
Celera1183,192,156 - 183,210,363 (-)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1180,634,114 - 180,654,661 (-)NCBIHuRef
CHM1_11211,231,296 - 211,251,831 (-)NCBICHM1_1
T2T-CHM13v2.01209,032,385 - 209,052,912 (-)NCBIT2T-CHM13v2.0
Irf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391192,835,420 - 192,854,344 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1192,835,419 - 192,854,331 (+)EnsemblGRCm39 Ensembl
GRCm381193,153,112 - 193,172,036 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,153,111 - 193,172,023 (+)EnsemblGRCm38mm10GRCm38
MGSCv371194,979,306 - 194,998,230 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361194,853,878 - 194,872,730 (+)NCBIMGSCv36mm8
Celera1200,028,192 - 200,047,120 (+)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.6NCBI
Irf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,200,876 - 107,220,083 (+)NCBIGRCr8
mRatBN7.213104,672,179 - 104,691,386 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13104,672,179 - 104,691,386 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,189,790 - 107,208,999 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,573,644 - 108,592,851 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013105,791,610 - 105,810,817 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013111,870,121 - 111,889,328 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13111,870,121 - 111,889,328 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,425,025 - 116,444,232 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413108,986,973 - 109,006,180 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.113109,176,076 - 109,195,282 (+)NCBI
Celera13104,102,428 - 104,121,635 (+)NCBICelera
Cytogenetic Map13q27NCBI
Irf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554892,415,925 - 2,437,837 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554892,404,773 - 2,434,729 (+)NCBIChiLan1.0ChiLan1.0
IRF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2139,591,466 - 39,612,943 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1139,557,629 - 39,581,840 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,361,612 - 185,382,516 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11190,226,722 - 190,247,145 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1190,226,727 - 190,247,145 (-)Ensemblpanpan1.1panPan2
IRF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,447,826 - 8,467,265 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,448,538 - 8,462,661 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha78,024,947 - 8,044,365 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.078,148,397 - 8,167,818 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl78,148,402 - 8,167,733 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.178,078,084 - 8,097,501 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.078,175,119 - 8,194,534 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.078,313,202 - 8,332,619 (-)NCBIUU_Cfam_GSD_1.0
Irf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934466,052,551 - 66,071,017 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365573,292,873 - 3,311,369 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365573,292,927 - 3,309,002 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,164,440 - 133,185,628 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,164,360 - 133,184,045 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29146,240,235 - 146,259,915 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IRF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12519,648,131 - 19,665,722 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605520,247,186 - 20,267,525 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000010209   ⟹   ENSHGLP00000010097
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248072,193,798 - 2,206,768 (+)Ensembl
RefSeq Acc Id: XM_004862015   ⟹   XP_004862072
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248072,192,768 - 2,207,183 (+)NCBI
RefSeq Acc Id: XM_013078654   ⟹   XP_012934108
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248072,192,765 - 2,207,183 (+)NCBI
RefSeq Acc Id: XM_021242415   ⟹   XP_021098074
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248072,190,721 - 2,207,183 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004862072 (Get FASTA)   NCBI Sequence Viewer  
  XP_012934108 (Get FASTA)   NCBI Sequence Viewer  
  XP_021098074 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB06336 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000010097
RefSeq Acc Id: XP_021098074   ⟸   XM_021242415
- Peptide Label: isoform X1
RefSeq Acc Id: XP_012934108   ⟸   XM_013078654
- Peptide Label: isoform X1
RefSeq Acc Id: XP_004862072   ⟸   XM_004862015
- Peptide Label: isoform X2
- UniProtKB: G5BAM5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000010097   ⟸   ENSHGLT00000010209


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007242 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000010209 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  2.60.200.10 UniProtKB/TrEMBL
InterPro Interferon_reg_fac_CS UniProtKB/TrEMBL
  Interferon_reg_fact_DNA-bd_dom UniProtKB/TrEMBL
  Interferon_reg_factor-3 UniProtKB/TrEMBL
  SMAD-like_dom_sf UniProtKB/TrEMBL
  SMAD_FHA_dom_sf UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report hgl:101711748 UniProtKB/TrEMBL
NCBI Gene Irf6 ENTREZGENE
PANTHER INTERFERON REGULATORY FACTOR UniProtKB/TrEMBL
  INTERFERON REGULATORY FACTOR 6 UniProtKB/TrEMBL
Pfam IRF UniProtKB/TrEMBL
  IRF-3 UniProtKB/TrEMBL
PRINTS INTFRNREGFCT UniProtKB/TrEMBL
PROSITE IRF_1 UniProtKB/TrEMBL
  IRF_2 UniProtKB/TrEMBL
SMART IRF UniProtKB/TrEMBL
  IRF-3 UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF49879 UniProtKB/TrEMBL
UniProt G5BAM5 ENTREZGENE, UniProtKB/TrEMBL