Styk1 (serine/threonine/tyrosine kinase 1) - Rat Genome Database

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Gene: Styk1 (serine/threonine/tyrosine kinase 1) Heterocephalus glaber
Analyze
Symbol: Styk1
Name: serine/threonine/tyrosine kinase 1
RGD ID: 18906605
Description: ENCODES a protein that exhibits ATP binding (inferred); kinase activity (inferred); protein kinase activity (inferred); INVOLVED IN cell surface receptor protein tyrosine kinase signaling pathway (inferred); ASSOCIATED WITH genetic disease (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Tyrosine-protein kinase STYK1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475227,295,114 - 27,333,517 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475227,294,428 - 27,334,347 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Styk1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475227,295,114 - 27,333,517 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475227,294,428 - 27,334,347 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
STYK1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,618,923 - 10,674,052 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,618,923 - 10,674,318 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,771,522 - 10,826,651 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,662,805 - 10,717,906 (-)NCBINCBI36Build 36hg18NCBI36
Build 341210,662,804 - 10,717,906NCBI
Celera1215,919,887 - 15,975,209 (-)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1210,500,495 - 10,555,642 (-)NCBIHuRef
CHM1_11210,740,892 - 10,796,266 (-)NCBICHM1_1
T2T-CHM13v2.01210,492,227 - 10,547,157 (-)NCBIT2T-CHM13v2.0
Styk1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396131,276,096 - 131,330,532 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6131,276,105 - 131,330,560 (-)EnsemblGRCm39 Ensembl
GRCm386131,299,133 - 131,353,836 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6131,299,142 - 131,353,597 (-)EnsemblGRCm38mm10GRCm38
MGSCv376131,249,162 - 131,263,845 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366131,264,837 - 131,279,520 (-)NCBIMGSCv36mm8
Celera6136,338,911 - 136,354,908 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.44NCBI
Styk1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84166,779,030 - 166,829,310 (-)NCBIGRCr8
mRatBN7.24165,047,613 - 165,097,890 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4165,048,440 - 165,096,440 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.04165,528,027 - 165,543,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4165,529,294 - 165,541,314 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04228,090,097 - 228,138,926 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44168,993,921 - 169,005,941 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera4153,658,246 - 153,673,584 (-)NCBICelera
Cytogenetic Map4q42NCBI
Styk1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554137,163,253 - 7,189,322 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554137,127,373 - 7,188,492 (+)NCBIChiLan1.0ChiLan1.0
STYK1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21016,087,902 - 16,143,975 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11216,082,374 - 16,140,743 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,642,786 - 10,700,727 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11210,911,351 - 10,966,630 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1210,911,351 - 10,967,149 (-)Ensemblpanpan1.1panPan2
STYK1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12735,087,835 - 35,117,233 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2735,087,792 - 35,117,975 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2711,411,271 - 11,444,287 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02735,433,127 - 35,466,250 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2735,432,852 - 35,465,126 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12735,315,888 - 35,348,839 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02735,261,744 - 35,294,808 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02711,026,868 - 11,059,723 (-)NCBIUU_Cfam_GSD_1.0
Styk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494596,768,682 - 96,812,055 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493715894,034 - 110,364 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493715894,023 - 110,364 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
STYK1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl561,397,025 - 61,421,406 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1561,395,553 - 61,418,696 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2564,096,988 - 64,143,254 (+)NCBISscrofa10.2Sscrofa10.2susScr3
STYK1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,420,178 - 10,475,523 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,419,664 - 10,454,878 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660892,498,530 - 2,553,706 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000013564   ⟹   ENSHGLP00000013424
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475227,295,114 - 27,318,581 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000013565   ⟹   ENSHGLP00000013425
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475227,295,767 - 27,333,517 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000013566   ⟹   ENSHGLP00000013426
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462475227,295,767 - 27,307,988 (-)Ensembl
RefSeq Acc Id: XM_004845892   ⟹   XP_004845949
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,294,428 - 27,318,855 (-)NCBI
RefSeq Acc Id: XM_021259181   ⟹   XP_021114840
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,318,878 (-)NCBI
RefSeq Acc Id: XM_021259182   ⟹   XP_021114841
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,318,479 (-)NCBI
RefSeq Acc Id: XM_021259183   ⟹   XP_021114842
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,318,338 (-)NCBI
RefSeq Acc Id: XM_021259184   ⟹   XP_021114843
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,319,188 (-)NCBI
RefSeq Acc Id: XM_021259185   ⟹   XP_021114844
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,334,346 (-)NCBI
RefSeq Acc Id: XM_021259186   ⟹   XP_021114845
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,319,188 (-)NCBI
RefSeq Acc Id: XM_021259187   ⟹   XP_021114846
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,334,347 (-)NCBI
RefSeq Acc Id: XM_021259188   ⟹   XP_021114847
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,317,611 (-)NCBI
RefSeq Acc Id: XM_021259189   ⟹   XP_021114848
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462475227,295,767 - 27,334,347 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_004845949   ⟸   XM_004845892
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114848   ⟸   XM_021259189
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114846   ⟸   XM_021259187
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114844   ⟸   XM_021259185
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114845   ⟸   XM_021259186
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114843   ⟸   XM_021259184
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114840   ⟸   XM_021259181
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114841   ⟸   XM_021259182
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114842   ⟸   XM_021259183
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021114847   ⟸   XM_021259188
- UniProtKB: G5BE04 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000013426   ⟸   ENSHGLT00000013566
RefSeq Acc Id: ENSHGLP00000013425   ⟸   ENSHGLT00000013565
RefSeq Acc Id: ENSHGLP00000013424   ⟸   ENSHGLT00000013564


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000009598 Ensembl, ENTREZGENE
  ENSHGLG00100003122 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000013564 ENTREZGENE
  ENSHGLT00000013565 ENTREZGENE
  ENSHGLT00100004164 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
KEGG Report hgl:101711283 UniProtKB/TrEMBL
NCBI Gene Styk1 ENTREZGENE
PANTHER SERINE/THREONINE/TYROSINE KINASE 1 UniProtKB/TrEMBL
  TYROSINE-PROTEIN KINASE RECEPTOR UniProtKB/TrEMBL
Pfam PK_Tyr_Ser-Thr UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt G5BE04 ENTREZGENE, UniProtKB/TrEMBL