Ift74 (intraflagellar transport 74) - Rat Genome Database

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Gene: Ift74 (intraflagellar transport 74) Heterocephalus glaber
Analyze
Symbol: Ift74
Name: intraflagellar transport 74
RGD ID: 18906375
Description: ENCODES a protein that exhibits beta-tubulin binding (inferred); chromatin binding (inferred); INVOLVED IN determination of left/right symmetry (ortholog); epidermis development (ortholog); heart development (ortholog); ASSOCIATED WITH asphyxiating thoracic dystrophy (ortholog); autism spectrum disorder (ortholog); Bardet-Biedl syndrome 22 (ortholog); FOUND IN intraciliary transport particle B (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: intraflagellar transport 74 homolog; intraflagellar transport protein 74 homolog
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473631,188,987 - 31,306,815 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473631,188,963 - 31,308,872 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Ift74
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473631,188,987 - 31,306,815 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473631,188,963 - 31,308,872 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
IFT74
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38926,947,110 - 27,066,134 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl926,947,039 - 27,066,134 (+)EnsemblGRCh38hg38GRCh38
GRCh37926,947,108 - 27,066,132 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36926,937,037 - 27,052,931 (+)NCBINCBI36Build 36hg18NCBI36
Build 34926,946,409 - 27,052,802NCBI
Celera926,875,190 - 26,991,082 (+)NCBICelera
Cytogenetic Map9p21.2NCBI
HuRef926,899,912 - 27,015,729 (+)NCBIHuRef
CHM1_1926,946,816 - 27,062,719 (+)NCBICHM1_1
T2T-CHM13v2.0926,957,713 - 27,076,715 (+)NCBIT2T-CHM13v2.0
Ift74
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39494,491,503 - 94,581,470 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl494,502,728 - 94,581,466 (+)EnsemblGRCm39 Ensembl
GRCm38494,603,266 - 94,693,233 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl494,614,491 - 94,693,229 (+)EnsemblGRCm38mm10GRCm38
MGSCv37494,281,211 - 94,359,924 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36494,146,847 - 94,185,247 (+)NCBIMGSCv36mm8
Celera493,023,677 - 93,103,044 (+)NCBICelera
Cytogenetic Map4C5NCBI
cM Map443.34NCBI
Ift74
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85114,576,106 - 114,679,581 (+)NCBIGRCr8
mRatBN7.25109,460,372 - 109,563,839 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5109,474,255 - 109,563,833 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5112,052,931 - 112,142,409 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05113,778,717 - 113,868,197 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05113,840,948 - 113,930,430 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05113,579,065 - 113,682,485 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5113,592,919 - 113,682,484 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05117,523,747 - 117,629,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45114,913,347 - 115,003,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15114,918,572 - 115,009,188 (+)NCBI
Celera5108,101,293 - 108,191,093 (+)NCBICelera
Cytogenetic Map5q33NCBI
Ift74
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554727,775,981 - 7,872,423 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554727,779,705 - 7,872,423 (-)NCBIChiLan1.0ChiLan1.0
IFT74
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21197,482,355 - 97,588,966 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1997,485,095 - 97,597,750 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0926,802,459 - 26,912,292 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1927,409,962 - 27,514,756 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl927,415,565 - 27,514,558 (+)Ensemblpanpan1.1panPan2
IFT74
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11145,159,124 - 45,242,019 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1145,161,086 - 45,242,012 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1143,834,528 - 43,919,561 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01146,103,920 - 46,188,986 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1146,105,889 - 46,188,982 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11144,761,014 - 44,845,589 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01144,650,812 - 44,735,508 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01145,397,519 - 45,482,097 (+)NCBIUU_Cfam_GSD_1.0
Ift74
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947160,007,880 - 160,079,709 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366112,588,695 - 2,660,532 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366112,588,711 - 2,660,496 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IFT74
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1196,086,072 - 196,173,880 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11196,084,498 - 196,173,880 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21218,533,803 - 218,621,870 (-)NCBISscrofa10.2Sscrofa10.2susScr3


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_013069765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_021252943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002392527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_002392528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01013442 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01013443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01013444 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01013445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01013446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01013447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01001025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000010661   ⟹   ENSHGLP00000010544
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473631,188,987 - 31,306,815 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000010662   ⟹   ENSHGLP00000010545
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473631,191,510 - 31,237,861 (+)Ensembl
RefSeq Acc Id: XM_013069765   ⟹   XP_012925219
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,188,965 - 31,269,837 (+)NCBI
RefSeq Acc Id: XM_021252934   ⟹   XP_021108593
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,191,510 - 31,308,872 (+)NCBI
RefSeq Acc Id: XM_021252935   ⟹   XP_021108594
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,188,965 - 31,308,872 (+)NCBI
RefSeq Acc Id: XM_021252937   ⟹   XP_021108596
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,188,964 - 31,308,872 (+)NCBI
RefSeq Acc Id: XM_021252938   ⟹   XP_021108597
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,189,317 - 31,308,872 (+)NCBI
RefSeq Acc Id: XM_021252939   ⟹   XP_021108598
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,191,510 - 31,308,872 (+)NCBI
RefSeq Acc Id: XM_021252940   ⟹   XP_021108599
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,194,716 - 31,308,872 (+)NCBI
RefSeq Acc Id: XM_021252942   ⟹   XP_021108601
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,188,963 - 31,298,594 (+)NCBI
RefSeq Acc Id: XM_021252943   ⟹   XP_021108602
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,188,963 - 31,236,955 (+)NCBI
RefSeq Acc Id: XR_002392527
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,191,510 - 31,308,872 (+)NCBI
RefSeq Acc Id: XR_002392528
Type: NON-CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473631,188,964 - 31,299,552 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021108601   ⟸   XM_021252942
- Peptide Label: isoform X4
RefSeq Acc Id: XP_021108602   ⟸   XM_021252943
- Peptide Label: isoform X5
RefSeq Acc Id: XP_021108596   ⟸   XM_021252937
- Peptide Label: isoform X1
- UniProtKB: G5BPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108594   ⟸   XM_021252935
- Peptide Label: isoform X1
- UniProtKB: G5BPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012925219   ⟸   XM_013069765
- Peptide Label: isoform X6
RefSeq Acc Id: XP_021108597   ⟸   XM_021252938
- Peptide Label: isoform X1
- UniProtKB: G5BPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108593   ⟸   XM_021252934
- Peptide Label: isoform X1
- UniProtKB: G5BPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108598   ⟸   XM_021252939
- Peptide Label: isoform X2
- UniProtKB: G5BPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021108599   ⟸   XM_021252940
- Peptide Label: isoform X3
- UniProtKB: G5BPW8 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000010544   ⟸   ENSHGLT00000010661
RefSeq Acc Id: ENSHGLP00000010545   ⟸   ENSHGLT00000010662


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000007564 Ensembl, ENTREZGENE
  ENSHGLG00100002966 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000010661 ENTREZGENE
  ENSHGLT00000010662 ENTREZGENE
  ENSHGLT00100047601 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.1490 UniProtKB/TrEMBL
InterPro IFT74 UniProtKB/TrEMBL
NCBI Gene Ift74 ENTREZGENE
PANTHER INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG UniProtKB/TrEMBL
  PTHR31432 UniProtKB/TrEMBL
UniProt A0A0P6K7U1_HETGA UniProtKB/TrEMBL
  G5BPW8 ENTREZGENE, UniProtKB/TrEMBL