Zeb1 (zinc finger E-box binding homeobox 1) - Rat Genome Database

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Gene: Zeb1 (zinc finger E-box binding homeobox 1) Heterocephalus glaber
Analyze
Symbol: Zeb1
Name: zinc finger E-box binding homeobox 1
RGD ID: 18906191
Description: ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); double-stranded DNA binding (ortholog); INVOLVED IN animal organ development (ortholog); cartilage development (ortholog); cell population proliferation (ortholog); ASSOCIATED WITH acute myocardial infarction (ortholog); Breast Neoplasms (ortholog); corneal dystrophy (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: zinc finger E-box-binding homeobox 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248053,964,450 - 4,042,527 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248053,964,448 - 4,044,546 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytosol  (ISO)
nucleoplasm  (ISO)
nucleus  (IEA)

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Zeb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248053,964,450 - 4,042,527 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248053,964,448 - 4,044,546 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ZEB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381031,318,417 - 31,529,804 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1031,318,495 - 31,529,814 (+)EnsemblGRCh38hg38GRCh38
GRCh371031,607,346 - 31,818,732 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361031,648,148 - 31,856,742 (+)NCBINCBI36Build 36hg18NCBI36
Build 341031,648,147 - 31,856,740NCBI
Celera1031,373,372 - 31,583,958 (+)NCBICelera
Cytogenetic Map10p11.22NCBI
HuRef1031,330,231 - 31,538,974 (+)NCBIHuRef
CHM1_11031,608,067 - 31,818,701 (+)NCBICHM1_1
T2T-CHM13v2.01031,348,155 - 31,559,554 (+)NCBIT2T-CHM13v2.0
Zeb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39185,591,330 - 5,775,468 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl185,591,860 - 5,775,467 (+)EnsemblGRCm39 Ensembl
GRCm38185,591,327 - 5,775,468 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl185,591,860 - 5,775,467 (+)EnsemblGRCm38mm10GRCm38
MGSCv37185,591,889 - 5,774,909 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36185,591,889 - 5,774,909 (+)NCBIMGSCv36mm8
Celera185,749,281 - 5,819,757 (+)NCBICelera
Cytogenetic Map18A1NCBI
cM Map184.42NCBI
Zeb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81756,644,397 - 56,811,155 (-)NCBIGRCr8
mRatBN7.21751,948,948 - 52,116,018 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1751,948,948 - 52,115,214 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1755,134,749 - 55,300,937 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01759,137,668 - 59,303,854 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01753,287,135 - 53,453,509 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01754,656,627 - 54,714,920 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1754,658,463 - 54,714,914 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01752,353,064 - 52,373,420 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41760,177,150 - 60,198,584 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11760,187,896 - 60,245,300 (-)NCBI
Celera1747,960,914 - 48,019,394 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Zeb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542923,010,790 - 23,198,250 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542923,011,627 - 23,198,188 (+)NCBIChiLan1.0ChiLan1.0
ZEB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2843,969,716 - 44,179,649 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11043,974,837 - 44,184,975 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01031,449,202 - 31,659,534 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11032,043,863 - 32,253,550 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1032,046,491 - 32,253,550 (+)Ensemblpanpan1.1panPan2
ZEB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1215,300,401 - 15,481,535 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl215,299,723 - 15,481,495 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha212,788,320 - 12,969,363 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0213,536,487 - 13,717,784 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl213,501,815 - 13,717,743 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1212,976,357 - 13,157,263 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0212,866,906 - 13,048,214 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0213,140,991 - 13,322,104 (-)NCBIUU_Cfam_GSD_1.0
Zeb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934410,517,823 - 10,676,265 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493657417,684 - 178,293 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493657417,643 - 175,762 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZEB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1042,013,084 - 42,214,205 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11042,013,114 - 42,216,139 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21046,547,219 - 46,726,896 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZEB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1930,674,893 - 30,862,682 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl930,674,578 - 30,863,250 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605639,637,685 - 39,830,491 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000026732   ⟹   ENSHGLP00000026496
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248053,964,450 - 4,042,527 (+)Ensembl
RefSeq Acc Id: XM_021242083   ⟹   XP_021097742
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248053,964,448 - 4,044,546 (+)NCBI
RefSeq Acc Id: XM_021242084   ⟹   XP_021097743
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248053,964,448 - 4,044,546 (+)NCBI
RefSeq Acc Id: XM_021242085   ⟹   XP_021097744
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248054,026,297 - 4,044,546 (+)NCBI
Protein Sequences
Protein RefSeqs XP_021097742 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097743 (Get FASTA)   NCBI Sequence Viewer  
  XP_021097744 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000026496
RefSeq Acc Id: XP_021097742   ⟸   XM_021242083
- Peptide Label: isoform X1
- UniProtKB: G5BE31 (UniProtKB/TrEMBL),   A0AAX6RLS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097743   ⟸   XM_021242084
- Peptide Label: isoform X1
- UniProtKB: G5BE31 (UniProtKB/TrEMBL),   A0AAX6RLS4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021097744   ⟸   XM_021242085
- Peptide Label: isoform X2
- UniProtKB: A0AAX6RMS3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000026496   ⟸   ENSHGLT00000026732


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018844 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000026732 ENTREZGENE
Gene3D-CATH Classic Zinc Finger UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
InterPro Di19_Zn-bd UniProtKB/TrEMBL
  Homeobox-like_sf UniProtKB/TrEMBL
  Homeobox_dom UniProtKB/TrEMBL
  Znf_C2H2_sf UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/TrEMBL
  ZnF_E-box_Homeobox UniProtKB/TrEMBL
NCBI Gene Zeb1 ENTREZGENE
PANTHER HISTONE H4 TRANSCRIPTION FACTOR-RELATED UniProtKB/TrEMBL
  ZINC FINGER E-BOX-BINDING HOMEOBOX 1 UniProtKB/TrEMBL
Pfam zf-C2H2 UniProtKB/TrEMBL
  zf-Di19 UniProtKB/TrEMBL
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
  ZnF_C2H2 UniProtKB/TrEMBL
Superfamily-SCOP beta-beta-alpha zinc fingers UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
UniProt A0AAX6RLS4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6RMS3 ENTREZGENE, UniProtKB/TrEMBL
  G5BE31 ENTREZGENE, UniProtKB/TrEMBL