Epgn (epithelial mitogen) - Rat Genome Database

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Gene: Epgn (epithelial mitogen) Heterocephalus glaber
Analyze
Symbol: Epgn
Name: epithelial mitogen
RGD ID: 18906065
Description: ENCODES a protein that exhibits epidermal growth factor receptor binding (inferred); growth factor activity (inferred); receptor ligand activity (inferred); INVOLVED IN angiogenesis (ortholog); MAPK cascade (ortholog); positive regulation of MAPK cascade (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; FOUND IN extracellular space (ortholog); plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Epigen
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247301,403,915 - 1,412,610 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Epgn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247301,403,915 - 1,412,610 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EPGN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38474,308,470 - 74,316,789 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl474,308,470 - 74,316,789 (+)EnsemblGRCh38hg38GRCh38
GRCh37475,174,187 - 75,182,506 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36475,393,068 - 75,398,171 (+)NCBINCBI36Build 36hg18NCBI36
Celera472,534,457 - 72,539,560 (+)NCBICelera
Cytogenetic Map4q13.3NCBI
HuRef470,985,134 - 70,993,467 (+)NCBIHuRef
CHM1_1475,210,022 - 75,218,355 (+)NCBICHM1_1
T2T-CHM13v2.0477,652,095 - 77,660,414 (+)NCBIT2T-CHM13v2.0
Epgn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39591,175,376 - 91,183,071 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl591,175,323 - 91,183,074 (+)EnsemblGRCm39 Ensembl
GRCm38591,027,517 - 91,035,212 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl591,027,464 - 91,035,215 (+)EnsemblGRCm38mm10GRCm38
MGSCv37591,456,543 - 91,464,238 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36592,102,717 - 92,110,412 (+)NCBIMGSCv36mm8
Celera589,163,266 - 89,170,925 (+)NCBICelera
Cytogenetic Map5E1NCBI
cM Map544.78NCBI
Epgn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81417,360,968 - 17,369,000 (-)NCBIGRCr8
mRatBN7.21417,076,774 - 17,084,806 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1417,076,774 - 17,084,806 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1417,077,610 - 17,085,647 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01418,396,535 - 18,404,572 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01417,088,653 - 17,096,690 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01418,627,103 - 18,635,135 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1418,626,644 - 18,634,309 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01418,534,970 - 18,543,093 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,573,036 - 18,579,934 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1416,454,534 - 16,462,566 (-)NCBICelera
Cytogenetic Map14p22NCBI
Epgn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955474564,329 - 573,014 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955474564,329 - 573,014 (+)NCBIChiLan1.0ChiLan1.0
EPGN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2355,743,457 - 55,752,425 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1455,932,463 - 55,941,448 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0449,875,419 - 49,884,234 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1455,708,072 - 55,716,868 (-)NCBIpanpan1.1PanPan1.1panPan2
EPGN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11362,803,595 - 62,811,581 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1362,803,654 - 62,810,274 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1362,490,822 - 62,498,846 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01363,632,685 - 63,640,709 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1363,630,887 - 63,640,714 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11363,247,466 - 63,255,482 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01362,729,267 - 62,737,285 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01363,872,330 - 63,880,347 (+)NCBIUU_Cfam_GSD_1.0
Epgn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440528512,935,639 - 12,944,151 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365981,389,100 - 1,396,514 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365981,389,129 - 1,396,508 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPGN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl870,292,467 - 70,300,149 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1870,266,867 - 70,301,250 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2874,389,477 - 74,395,775 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPGN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1722,842,830 - 22,852,867 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl722,844,202 - 22,853,104 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660371,132,852 - 1,143,249 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004833913   ⟹   XP_004833970
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247301,403,915 - 1,412,610 (-)NCBI
RefSeq Acc Id: XM_021255334   ⟹   XP_021110993
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247301,404,557 - 1,412,366 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004833970 (Get FASTA)   NCBI Sequence Viewer  
  XP_021110993 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB12767 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000040262
  ENSHGLP00100030361
Reference Protein Sequences
RefSeq Acc Id: XP_004833970   ⟸   XM_004833913
- Peptide Label: isoform X2
- UniProtKB: G5BU09 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021110993   ⟸   XM_021255334
- Peptide Label: isoform X1


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000036014 UniProtKB/TrEMBL
  ENSHGLG00100051797 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000068059 UniProtKB/TrEMBL
  ENSHGLT00100066539 UniProtKB/TrEMBL
Gene3D-CATH Laminin UniProtKB/TrEMBL
InterPro EGF-like_dom UniProtKB/TrEMBL
KEGG Report hgl:101704232 UniProtKB/TrEMBL
NCBI Gene Epgn ENTREZGENE
PANTHER EPIGEN UniProtKB/TrEMBL
  PTHR10740 UniProtKB/TrEMBL
PRINTS EGFTGF UniProtKB/TrEMBL
PROSITE EGF_1 UniProtKB/TrEMBL
  EGF_2 UniProtKB/TrEMBL
  EGF_3 UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/TrEMBL
UniProt G5BU09 ENTREZGENE, UniProtKB/TrEMBL