Diaph3 (diaphanous related formin 3) - Rat Genome Database

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Gene: Diaph3 (diaphanous related formin 3) Heterocephalus glaber
Analyze
Symbol: Diaph3
Name: diaphanous related formin 3
RGD ID: 18905911
Description: ENCODES a protein that exhibits cytoskeletal protein binding (ortholog); microtubule binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN actin crosslink formation (ortholog); actin cytoskeleton organization (ortholog); actin filament bundle assembly (ortholog); ASSOCIATED WITH autosomal dominant auditory neuropathy 1 (ortholog); chromosome 13q14 deletion syndrome (ortholog); congenital dyserythropoietic anemia (ortholog); FOUND IN actin filament bundle (ortholog); cleavage furrow (ortholog); cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: diaphanous homolog 3; diaphanous-like protein 3; protein diaphanous homolog 3
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474821,045,085 - 21,383,605 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474820,937,242 - 21,439,554 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Diaph3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474821,045,085 - 21,383,605 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474820,937,242 - 21,439,554 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DIAPH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381359,665,583 - 60,163,928 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1359,665,583 - 60,163,928 (-)EnsemblGRCh38hg38GRCh38
GRCh371360,239,717 - 60,738,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361359,137,718 - 59,636,120 (-)NCBINCBI36Build 36hg18NCBI36
Build 341359,246,300 - 59,485,300NCBI
Celera1341,197,875 - 41,696,297 (-)NCBICelera
Cytogenetic Map13q21.2NCBI
HuRef1341,255,633 - 41,428,315 (-)NCBIHuRef
HuRef1340,931,297 - 41,246,568 (-)NCBIHuRef
CHM1_11360,207,261 - 60,705,825 (-)NCBICHM1_1
T2T-CHM13v2.01358,885,077 - 59,383,567 (-)NCBIT2T-CHM13v2.0
Diaph3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391486,892,793 - 87,378,683 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1486,892,803 - 87,378,671 (-)EnsemblGRCm39 Ensembl
GRCm381486,655,357 - 87,141,247 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1486,655,367 - 87,141,235 (-)EnsemblGRCm38mm10GRCm38
MGSCv371487,056,130 - 87,540,921 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361485,488,070 - 85,972,861 (-)NCBIMGSCv36mm8
Celera1484,160,281 - 84,666,148 (-)NCBICelera
Cytogenetic Map14E1NCBI
cM Map1443.95NCBI
Diaph3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81568,951,992 - 69,421,623 (-)NCBIGRCr8
mRatBN7.21562,543,375 - 63,013,060 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1562,543,375 - 63,012,975 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1566,656,922 - 67,116,561 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01567,742,429 - 68,202,078 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01564,634,100 - 65,103,658 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01569,928,507 - 70,400,077 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1570,039,424 - 70,399,924 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01573,538,942 - 74,007,617 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41568,905,784 - 69,267,707 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1562,058,201 - 62,525,728 (-)NCBICelera
Cytogenetic Map15q12NCBI
Diaph3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540444,653,501 - 45,105,966 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540444,653,308 - 45,106,943 (+)NCBIChiLan1.0ChiLan1.0
DIAPH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21461,191,418 - 61,681,129 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11359,783,100 - 60,272,789 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01340,846,270 - 41,335,920 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11359,568,025 - 60,056,893 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1359,676,307 - 60,056,672 (-)Ensemblpanpan1.1panPan2
DIAPH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12215,573,485 - 16,078,580 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2215,573,629 - 16,079,031 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2215,549,820 - 16,056,525 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02215,808,339 - 16,315,836 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2215,808,334 - 16,315,281 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12215,507,946 - 16,015,886 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02215,533,302 - 16,040,579 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02215,547,618 - 16,055,719 (-)NCBIUU_Cfam_GSD_1.0
Diaph3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945144,087,524 - 144,542,722 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367051,380,445 - 1,731,280 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367051,381,025 - 1,833,890 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DIAPH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1132,492,740 - 32,994,844 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11132,492,735 - 32,994,854 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21134,600,374 - 34,681,530 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DIAPH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1337,455,326 - 37,951,237 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660575,747,366 - 6,261,536 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_004844304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01028255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028264 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AHKG01028269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GEBF01003278 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JH169548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSHGLT00000026270   ⟹   ENSHGLP00000026040
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462474821,045,085 - 21,383,605 (-)Ensembl
RefSeq Acc Id: XM_004844304   ⟹   XP_004844361
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462474820,937,242 - 21,439,554 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004844361 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB07038 (Get FASTA)   NCBI Sequence Viewer  
  JAO00355 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004844361   ⟸   XM_004844304
- UniProtKB: A0A0P6J7Y2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000026040   ⟸   ENSHGLT00000026270


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000018541 Ensembl
Gene3D-CATH 1.10.20.40 UniProtKB/TrEMBL
  1.20.58.2220 UniProtKB/TrEMBL
  1.20.58.630 UniProtKB/TrEMBL
  1.25.10.10 UniProtKB/TrEMBL
  6.10.30.30 UniProtKB/TrEMBL
  Formin, FH3 diaphanous domain UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/TrEMBL
  DAD_dom UniProtKB/TrEMBL
  DIA_GBD_sf UniProtKB/TrEMBL
  FH2_Formin UniProtKB/TrEMBL
  FH2_Formin_sf UniProtKB/TrEMBL
  FH3_dom UniProtKB/TrEMBL
  GBD/FH3_dom UniProtKB/TrEMBL
  GTPase-bd UniProtKB/TrEMBL
NCBI Gene Diaph3 ENTREZGENE
PANTHER PROTEIN DIAPHANOUS UniProtKB/TrEMBL
  PTHR45691:SF9 UniProtKB/TrEMBL
Pfam Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
PROSITE DAD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
  GBD_FH3 UniProtKB/TrEMBL
SMART Drf_FH3 UniProtKB/TrEMBL
  Drf_GBD UniProtKB/TrEMBL
  FH2 UniProtKB/TrEMBL
Superfamily-SCOP Formin homology 2 domain (FH2 domain) UniProtKB/TrEMBL
  SSF48371 UniProtKB/TrEMBL
UniProt A0A0P6J7Y2 ENTREZGENE, UniProtKB/TrEMBL