Heyl (hes related family bHLH transcription factor with YRPW motif like) - Rat Genome Database

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Gene: Heyl (hes related family bHLH transcription factor with YRPW motif like) Heterocephalus glaber
Analyze
Symbol: Heyl
Name: hes related family bHLH transcription factor with YRPW motif like
RGD ID: 18905905
Description: ENCODES a protein that exhibits AF-1 domain binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription factor activity (ortholog); INVOLVED IN atrioventricular valve morphogenesis (ortholog); cardiac epithelial to mesenchymal transition (ortholog); cardiac ventricle morphogenesis (ortholog); PARTICIPATES IN Notch signaling pathway; ASSOCIATED WITH Breast Neoplasms (ortholog); Carotid Artery Injuries (ortholog); Charcot-Marie-Tooth disease dominant intermediate C (ortholog); FOUND IN cytoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Hairy/enhancer-of-split related with YRPW motif-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,122,079 - 22,135,252 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,118,995 - 22,135,280 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (ISO)
nucleus  (IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Heyl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,122,079 - 22,135,252 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,118,995 - 22,135,280 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
HEYL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38139,623,435 - 39,639,643 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl139,623,435 - 39,639,643 (-)EnsemblGRCh38hg38GRCh38
GRCh37140,089,107 - 40,105,315 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36139,861,690 - 39,877,935 (-)NCBINCBI36Build 36hg18NCBI36
Build 34139,758,917 - 39,774,411NCBI
Celera138,370,855 - 38,387,100 (-)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef138,207,488 - 38,223,733 (-)NCBIHuRef
CHM1_1140,204,476 - 40,220,725 (-)NCBICHM1_1
T2T-CHM13v2.0139,487,908 - 39,508,063 (-)NCBIT2T-CHM13v2.0
Heyl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394123,127,349 - 123,143,663 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4123,127,349 - 123,143,668 (+)EnsemblGRCm39 Ensembl
GRCm384123,233,556 - 123,249,870 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4123,233,556 - 123,249,875 (+)EnsemblGRCm38mm10GRCm38
MGSCv374122,910,799 - 122,927,113 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364122,736,156 - 122,752,173 (+)NCBIMGSCv36mm8
Celera4121,565,928 - 121,582,239 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.41NCBI
Heyl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,793,271 - 140,810,262 (+)NCBIGRCr8
mRatBN7.25135,508,160 - 135,525,152 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,508,160 - 135,525,152 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5138,214,573 - 138,231,698 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05139,984,540 - 140,001,666 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05139,991,677 - 140,008,802 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,923,914 - 140,940,905 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,923,914 - 140,940,905 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,713,817 - 144,730,808 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,544,185 - 142,561,176 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15142,549,721 - 142,563,036 (+)NCBI
Celera5134,047,073 - 134,064,064 (+)NCBICelera
Cytogenetic Map5q36NCBI
Heyl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545217,134,770 - 17,152,924 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545217,137,066 - 17,152,714 (-)NCBIChiLan1.0ChiLan1.0
HEYL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21187,182,481 - 187,198,009 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11186,320,121 - 186,335,647 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0138,913,549 - 38,929,798 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,240,114 - 40,256,300 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl140,240,118 - 40,256,933 (-)Ensemblpanpan1.1panPan2
Heyl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505855,678,981 - 55,688,610 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647421,505,149 - 21,510,624 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647421,503,763 - 21,513,392 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEYL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl695,442,661 - 95,459,575 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1695,442,655 - 95,459,597 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2688,532,056 - 88,547,809 (-)NCBISscrofa10.2Sscrofa10.2susScr3
HEYL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12093,230,189 - 93,246,549 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603323,571,967 - 23,587,587 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000017192   ⟹   ENSHGLP00000017021
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476422,122,079 - 22,135,252 (-)Ensembl
RefSeq Acc Id: XM_004851031   ⟹   XP_004851088
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476422,118,995 - 22,135,280 (-)NCBI
RefSeq Acc Id: XM_004851032   ⟹   XP_004851089
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476422,118,995 - 22,132,083 (-)NCBI
RefSeq Acc Id: XM_021263390   ⟹   XP_021119049
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476422,118,995 - 22,129,556 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004851088 (Get FASTA)   NCBI Sequence Viewer  
  XP_004851089 (Get FASTA)   NCBI Sequence Viewer  
  XP_021119049 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB16597 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000017021
  ENSHGLP00100037036
GenBank Protein JAO00642 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004851088   ⟸   XM_004851031
- Peptide Label: isoform X1
- UniProtKB: G5C4Y6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004851089   ⟸   XM_004851032
- Peptide Label: isoform X2
RefSeq Acc Id: XP_021119049   ⟸   XM_021263390
- Peptide Label: isoform X2
RefSeq Acc Id: ENSHGLP00000017021   ⟸   ENSHGLT00000017192


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000012182 Ensembl, ENTREZGENE
  ENSHGLG00100034949 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000017192 ENTREZGENE
  ENSHGLT00100084493 UniProtKB/TrEMBL
Gene3D-CATH 4.10.280.10 UniProtKB/TrEMBL
  6.10.250.980 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  Orange_dom UniProtKB/TrEMBL
KEGG Report hgl:101713703 UniProtKB/TrEMBL
NCBI Gene Heyl ENTREZGENE
PANTHER BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED UniProtKB/TrEMBL
  HAIRY/ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF-LIKE PROTEIN UniProtKB/TrEMBL
Pfam Hairy_orange UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
  ORANGE UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
  ORANGE UniProtKB/TrEMBL
Superfamily-SCOP Orange domain-like UniProtKB/TrEMBL
  SSF47459 UniProtKB/TrEMBL
UniProt G5C4Y6 ENTREZGENE, UniProtKB/TrEMBL