Slc22a2 (solute carrier family 22 member 2) - Rat Genome Database

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Gene: Slc22a2 (solute carrier family 22 member 2) Heterocephalus glaber
Analyze
Symbol: Slc22a2
Name: solute carrier family 22 member 2
RGD ID: 18905623
Description: ENCODES a protein that exhibits acetylcholine transmembrane transporter activity (ortholog); amine transmembrane transporter activity (ortholog); choline transmembrane transporter activity (ortholog); INVOLVED IN acetylcholine transport (ortholog); amine transport (ortholog); amino acid import across plasma membrane (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH 3-methylglutaconic aciduria with deafness, encephalopathy, and Leigh-like syndrome (ortholog); acute kidney failure (ortholog); end stage renal disease (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); cholinergic synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248552,623,547 - 2,659,742 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248552,623,595 - 2,661,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc22a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248552,623,547 - 2,659,742 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248552,623,595 - 2,661,739 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLC22A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386160,216,755 - 160,258,821 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6160,171,061 - 160,277,638 (-)EnsemblGRCh38hg38GRCh38
GRCh376160,637,787 - 160,679,853 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,557,780 - 160,599,949 (-)NCBINCBI36Build 36hg18NCBI36
Build 346160,608,201 - 160,650,370NCBI
Celera6161,284,724 - 161,329,224 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6158,107,747 - 158,154,417 (-)NCBIHuRef
CHM1_16160,900,027 - 160,942,556 (-)NCBICHM1_1
T2T-CHM13v2.06161,462,946 - 161,508,769 (-)NCBIT2T-CHM13v2.0
Slc22a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391712,803,076 - 12,847,376 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1712,803,019 - 12,847,375 (+)EnsemblGRCm39 Ensembl
GRCm381712,584,189 - 12,628,489 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,584,132 - 12,628,488 (+)EnsemblGRCm38mm10GRCm38
MGSCv371712,777,055 - 12,821,354 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,427,547 - 12,471,846 (+)NCBIMGSCv36mm8
Celera1712,614,783 - 12,660,660 (+)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.61NCBI
Slc22a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,668,817 - 50,711,019 (-)NCBIGRCr8
mRatBN7.2148,121,061 - 48,163,268 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl148,121,061 - 48,163,268 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,812,678 - 48,854,865 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,798,480 - 54,840,630 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,888,183 - 48,930,374 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,318,025 - 48,360,219 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,317,995 - 48,360,261 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,394,014 - 51,435,104 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,395,676 - 42,442,847 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,398,620 - 42,445,782 (-)NCBI
Celera143,920,665 - 43,963,268 (-)NCBICelera
Cytogenetic Map1q11NCBI
Slc22a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,567,212 - 20,609,105 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,567,241 - 20,608,281 (+)NCBIChiLan1.0ChiLan1.0
SLC22A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25180,320,892 - 180,367,795 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16178,223,301 - 178,271,798 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06158,058,226 - 158,150,917 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16163,066,654 - 163,158,469 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6163,065,317 - 163,158,931 (-)Ensemblpanpan1.1panPan2
SLC22A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,327,621 - 49,348,435 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,327,296 - 49,348,435 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha150,170,589 - 50,191,400 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,505,206 - 49,533,863 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,503,308 - 49,533,595 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,395,180 - 49,415,993 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,266,805 - 49,288,175 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,882,427 - 49,903,195 (-)NCBIUU_Cfam_GSD_1.0
Slc22a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946144,341,980 - 144,375,967 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648911,594,480 - 11,627,786 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648911,605,403 - 11,627,786 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC22A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,289,831 - 7,323,146 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,289,278 - 7,323,418 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.218,980,529 - 9,012,013 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC22A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,835,077 - 87,881,410 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,833,430 - 87,881,081 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604060,218,540 - 60,262,523 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000024750   ⟹   ENSHGLP00000024529
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248552,623,547 - 2,659,742 (+)Ensembl
RefSeq Acc Id: XM_004869005   ⟹   XP_004869062
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248552,623,601 - 2,661,739 (+)NCBI
RefSeq Acc Id: XM_004869006   ⟹   XP_004869063
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248552,623,595 - 2,661,739 (+)NCBI
RefSeq Acc Id: XM_004869007   ⟹   XP_004869064
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248552,623,597 - 2,661,739 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004869062 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869063 (Get FASTA)   NCBI Sequence Viewer  
  XP_004869064 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024529
Reference Protein Sequences
RefSeq Acc Id: XP_004869063   ⟸   XM_004869006
- Peptide Label: isoform X2
- UniProtKB: G5BC55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869064   ⟸   XM_004869007
- Peptide Label: isoform X3
- UniProtKB: G5BC55 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004869062   ⟸   XM_004869005
- Peptide Label: isoform X1
- UniProtKB: G5BC55 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000024529   ⟸   ENSHGLT00000024750


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017482 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000024750 ENTREZGENE
Gene3D-CATH MFS general substrate transporter like domains UniProtKB/TrEMBL
InterPro MFS_dom UniProtKB/TrEMBL
  MFS_sugar_transport-like UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/TrEMBL
  Orgcat_transp/SVOP UniProtKB/TrEMBL
  Sugar_transporter_CS UniProtKB/TrEMBL
NCBI Gene Slc22a2 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 22 MEMBER UniProtKB/TrEMBL
  SOLUTE CARRIER FAMILY 22 MEMBER 2 UniProtKB/TrEMBL
Pfam Sugar_tr UniProtKB/TrEMBL
PROSITE MFS UniProtKB/TrEMBL
  SUGAR_TRANSPORT_1 UniProtKB/TrEMBL
Superfamily-SCOP MFS general substrate transporter UniProtKB/TrEMBL
UniProt G5BC55 ENTREZGENE, UniProtKB/TrEMBL