Mcam (melanoma cell adhesion molecule) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Mcam (melanoma cell adhesion molecule) Heterocephalus glaber
Analyze
Symbol: Mcam
Name: melanoma cell adhesion molecule
RGD ID: 18905550
Description: ENCODES a protein that exhibits laminin receptor activity (inferred); INVOLVED IN angiogenesis (ortholog); glomerular filtration (ortholog); positive regulation of cell migration (ortholog); ASSOCIATED WITH autoimmune disease of the nervous system (ortholog); CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); FOUND IN external side of plasma membrane (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cell surface glycoprotein MUC18
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,673,060 - 14,681,423 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,671,524 - 14,681,151 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Mcam
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,673,060 - 14,681,423 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478414,671,524 - 14,681,151 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
MCAM
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,308,529 - 119,317,130 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,308,529 - 119,321,521 (-)EnsemblGRCh38hg38GRCh38
GRCh3711119,179,239 - 119,187,840 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,684,444 - 118,693,050 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411118,684,187 - 118,693,050NCBI
Celera11116,339,434 - 116,348,037 (-)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11115,119,937 - 115,128,540 (-)NCBIHuRef
CHM1_111119,065,786 - 119,074,389 (-)NCBICHM1_1
T2T-CHM13v2.011119,329,165 - 119,337,763 (-)NCBIT2T-CHM13v2.0
Mcam
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,045,958 - 44,054,024 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,045,766 - 44,054,024 (+)EnsemblGRCm39 Ensembl
GRCm38944,134,658 - 44,142,727 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,134,469 - 44,142,727 (+)EnsemblGRCm38mm10GRCm38
MGSCv37943,942,741 - 43,950,809 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36943,885,666 - 43,893,719 (+)NCBIMGSCv36mm8
Celera941,392,205 - 41,400,272 (+)NCBICelera
Cytogenetic Map9A5.1NCBI
cM Map924.68NCBI
Mcam
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,376,225 - 53,384,407 (+)NCBIGRCr8
mRatBN7.2844,479,391 - 44,487,575 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,479,376 - 44,487,571 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx849,974,482 - 49,982,684 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,253,193 - 48,261,397 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,124,029 - 46,132,210 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,472,824 - 48,481,005 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,472,824 - 48,481,001 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,091,191 - 47,099,630 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,105,632 - 47,127,936 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,130,370 - 47,135,903 (+)NCBI
Celera844,066,232 - 44,074,417 (+)NCBICelera
Cytogenetic Map8q22NCBI
Mcam
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,397,051 - 20,404,780 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541220,396,056 - 20,404,777 (-)NCBIChiLan1.0ChiLan1.0
MCAM
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29120,016,269 - 120,024,928 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111121,119,769 - 121,128,446 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011114,149,583 - 114,158,234 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111118,076,841 - 118,084,748 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11118,078,179 - 118,083,893 (-)Ensemblpanpan1.1panPan2
MCAM
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,590,252 - 14,598,901 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,567,238 - 14,598,149 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha514,643,495 - 14,652,026 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0514,533,623 - 14,542,154 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,510,591 - 14,542,153 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,672,708 - 14,680,319 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,575,921 - 14,584,454 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,616,078 - 14,624,610 (+)NCBIUU_Cfam_GSD_1.0
Mcam
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,314,589 - 101,328,572 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,237,010 - 4,244,462 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,235,914 - 4,244,981 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MCAM
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,512,784 - 46,522,083 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1946,506,375 - 46,522,091 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,546,351 - 51,557,212 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MCAM
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,682,631 - 110,691,717 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,684,458 - 110,691,707 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604315,343,344 - 15,351,927 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000023327   ⟹   ENSHGLP00000023112
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478414,673,060 - 14,681,423 (-)Ensembl
RefSeq Acc Id: XM_004856796   ⟹   XP_004856853
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478414,671,524 - 14,681,151 (-)NCBI
RefSeq Acc Id: XM_021237657   ⟹   XP_021093316
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478414,671,524 - 14,681,151 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004856853 (Get FASTA)   NCBI Sequence Viewer  
  XP_021093316 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000023112
  ENSHGLP00100061137
GenBank Protein JAO00046 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021093316   ⟸   XM_021237657
- Peptide Label: isoform X2
RefSeq Acc Id: XP_004856853   ⟸   XM_004856796
- Peptide Label: isoform X1
- UniProtKB: A0A0N8ETS2 (UniProtKB/TrEMBL),   G5BHP3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000023112   ⟸   ENSHGLT00000023327


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000016479 Ensembl, ENTREZGENE
  ENSHGLG00100018320 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000023327 ENTREZGENE
  ENSHGLT00100087565 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro CD80_C2-set UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Immunoglobulin UniProtKB/TrEMBL
NCBI Gene Mcam ENTREZGENE
PANTHER CELL SURFACE GLYCOPROTEIN MUC18 UniProtKB/TrEMBL
  CELL SURFACE GLYCOPROTEIN MUC18-RELATED UniProtKB/TrEMBL
Pfam C2-set_2 UniProtKB/TrEMBL
  Ig_3 UniProtKB/TrEMBL
  PF00047 UniProtKB/TrEMBL
  V-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A0N8ETS2 ENTREZGENE, UniProtKB/TrEMBL
  G5BHP3 ENTREZGENE, UniProtKB/TrEMBL