Dph3 (diphthamide biosynthesis 3) - Rat Genome Database

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Gene: Dph3 (diphthamide biosynthesis 3) Heterocephalus glaber
Analyze
Symbol: Dph3
Name: diphthamide biosynthesis 3
RGD ID: 18905070
Description: INVOLVED IN protein histidyl modification to diphthamide (ortholog); ASSOCIATED WITH 3p deletion syndrome (ortholog); genetic disease (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DPH3 homolog; DPH3, KTI11 homolog; DPH3-like protein
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248211,496,565 - 1,500,896 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248211,494,321 - 1,500,911 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:30032202  


Genomics

Comparative Map Data
Dph3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248211,496,565 - 1,500,896 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248211,494,321 - 1,500,911 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
DPH3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38316,257,061 - 16,264,943 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl316,257,061 - 16,264,969 (-)EnsemblGRCh38hg38GRCh38
GRCh37316,298,568 - 16,306,450 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36316,276,969 - 16,281,490 (-)NCBINCBI36Build 36hg18NCBI36
Build 34316,277,013 - 16,281,409NCBI
Celera316,237,487 - 16,245,416 (-)NCBICelera
Cytogenetic Map3p25.1NCBI
HuRef316,231,591 - 16,239,520 (-)NCBIHuRef
CHM1_1316,249,497 - 16,257,426 (-)NCBICHM1_1
T2T-CHM13v2.0316,258,288 - 16,266,169 (-)NCBIT2T-CHM13v2.0
Dph3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391431,802,474 - 31,807,649 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1431,802,523 - 31,807,686 (-)EnsemblGRCm39 Ensembl
GRCm381432,080,517 - 32,085,692 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1432,080,566 - 32,085,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv371432,893,748 - 32,898,851 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361430,909,578 - 30,914,591 (-)NCBIMGSCv36mm8
Celera1428,339,467 - 28,344,570 (-)NCBICelera
Cytogenetic Map14BNCBI
cM Map1419.4NCBI
Dph3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8167,294,580 - 7,299,996 (-)NCBIGRCr8
mRatBN7.2167,288,295 - 7,293,734 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl167,282,705 - 7,291,265 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx167,289,080 - 7,294,550 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0168,433,932 - 8,439,402 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0167,298,934 - 7,304,354 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0168,202,048 - 8,207,492 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl168,202,048 - 8,207,464 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0168,119,073 - 8,124,489 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4167,541,193 - 7,546,609 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera167,904,888 - 7,910,304 (+)NCBICelera
Cytogenetic Map16p16NCBI
Dph3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554308,544,314 - 8,550,276 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554308,544,314 - 8,550,276 (-)NCBIChiLan1.0ChiLan1.0
DPH3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2216,243,141 - 16,250,240 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1316,247,905 - 16,254,959 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0316,183,158 - 16,190,184 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1316,520,076 - 16,527,196 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl316,520,076 - 16,527,196 (-)Ensemblpanpan1.1panPan2
DPH3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12326,522,367 - 26,529,808 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2326,522,374 - 26,527,827 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2326,497,520 - 26,505,024 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02327,023,638 - 27,031,142 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2327,023,665 - 27,031,141 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12326,724,242 - 26,731,957 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02326,786,230 - 26,793,945 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02327,035,260 - 27,042,764 (+)NCBIUU_Cfam_GSD_1.0
Dph3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118175,907,489 - 175,913,939 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049364739,046,062 - 9,052,522 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DPH3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl133,391,823 - 3,395,856 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1133,391,833 - 3,395,856 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2133,582,105 - 3,586,124 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DPH3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11561,103,247 - 61,111,114 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1561,103,102 - 61,111,115 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604134,108,453 - 34,115,488 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000005518   ⟹   ENSHGLP00000005447
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248211,496,565 - 1,500,896 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000005519   ⟹   ENSHGLP00000005448
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248211,496,813 - 1,500,733 (-)Ensembl
RefSeq Acc Id: ENSHGLT00000005520   ⟹   ENSHGLP00000005449
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248211,500,026 - 1,500,733 (-)Ensembl
RefSeq Acc Id: XM_004864251   ⟹   XP_004864308
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248211,494,321 - 1,500,911 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004864308 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB10487 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000005447
  ENSHGLP00000049467
  ENSHGLP00100047850
GenBank Protein JAO00859 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_004864308   ⟸   XM_004864251
- UniProtKB: G5BMH6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000005447   ⟸   ENSHGLT00000005518
RefSeq Acc Id: ENSHGLP00000005449   ⟸   ENSHGLT00000005520
RefSeq Acc Id: ENSHGLP00000005448   ⟸   ENSHGLT00000005519


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000003993 Ensembl, ENTREZGENE
  ENSHGLG00000045426 UniProtKB/TrEMBL
  ENSHGLG00100038649 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000005518 ENTREZGENE
  ENSHGLT00000049575 UniProtKB/TrEMBL
  ENSHGLT00100049079 UniProtKB/TrEMBL
Gene3D-CATH 3.10.660.10 UniProtKB/TrEMBL
InterPro DHP_MB_dom UniProtKB/TrEMBL
  DHP_MB_sf UniProtKB/TrEMBL
KEGG Report hgl:101720523 UniProtKB/TrEMBL
NCBI Gene Dph3 ENTREZGENE
PANTHER DPH3 HOMOLOG UniProtKB/TrEMBL
  PTHR21454 UniProtKB/TrEMBL
Pfam zf-CSL UniProtKB/TrEMBL
PROSITE DPH_MB UniProtKB/TrEMBL
Superfamily-SCOP SSF144217 UniProtKB/TrEMBL
UniProt G5BMH6 ENTREZGENE, UniProtKB/TrEMBL