Cstf2 (cleavage stimulation factor subunit 2) - Rat Genome Database

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Gene: Cstf2 (cleavage stimulation factor subunit 2) Heterocephalus glaber
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Symbol: Cstf2
Name: cleavage stimulation factor subunit 2
RGD ID: 18904685
Description: ENCODES a protein that exhibits mRNA binding (inferred); RNA binding (inferred); INVOLVED IN cellular response to nerve growth factor stimulus (ortholog); PARTICIPATES IN 3'-end pre-mRNA processing pathway; RNA polymerase II transcription termination pathway; ASSOCIATED WITH autistic disorder (ortholog); autosomal hemophilia A (ortholog); developmental and epileptic encephalopathy 9 (ortholog); FOUND IN cleavage body (ortholog); nuclear body (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Cleavage stimulation factor 64 kDa subunit
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249021,755,308 - 1,780,826 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Cstf2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249021,755,308 - 1,780,826 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
CSTF2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X100,820,391 - 100,841,520 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX100,820,391 - 100,841,520 (+)EnsemblGRCh38hg38GRCh38
GRCh37X100,075,380 - 100,096,509 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X99,962,004 - 99,982,580 (+)NCBINCBI36Build 36hg18NCBI36
Build 34X99,881,528 - 99,902,066NCBI
CeleraX100,594,139 - 100,614,716 (+)NCBICelera
Cytogenetic MapXq22.1NCBI
HuRefX89,874,108 - 89,894,686 (+)NCBIHuRef
CHM1_1X99,968,275 - 99,988,854 (+)NCBICHM1_1
T2T-CHM13v2.0X99,262,925 - 99,284,058 (+)NCBIT2T-CHM13v2.0
Cstf2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X132,959,925 - 132,987,571 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX132,959,936 - 132,987,568 (+)EnsemblGRCm39 Ensembl
GRCm38X134,059,176 - 134,086,822 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX134,059,187 - 134,086,819 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X130,593,888 - 130,621,360 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X129,405,699 - 129,433,171 (+)NCBIMGSCv36mm8
CeleraX116,935,737 - 116,962,977 (+)NCBICelera
Cytogenetic MapXE3NCBI
cM MapX55.63NCBI
Cstf2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X101,546,809 - 101,572,760 (+)NCBIGRCr8
mRatBN7.2X97,253,559 - 97,279,476 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX97,253,586 - 97,279,476 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX98,927,891 - 98,953,618 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X102,437,661 - 102,463,386 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X99,941,058 - 99,966,783 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X104,882,726 - 104,909,746 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX104,882,704 - 104,909,739 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X104,716,784 - 104,742,717 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
CeleraX98,299,890 - 98,325,615 (+)NCBICelera
Cytogenetic MapXq32NCBI
Cstf2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555036,949,823 - 6,975,030 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555036,949,901 - 6,971,281 (+)NCBIChiLan1.0ChiLan1.0
CSTF2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X100,419,293 - 100,442,986 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X100,422,898 - 100,446,591 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X90,023,054 - 90,046,229 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X100,161,749 - 100,182,304 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX100,161,749 - 100,182,304 (+)Ensemblpanpan1.1panPan2
CSTF2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X74,758,399 - 74,782,470 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX74,758,496 - 74,782,194 (+)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X76,171,588 - 76,195,408 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX76,171,635 - 76,197,985 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X73,736,569 - 73,760,382 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X75,400,536 - 75,424,341 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X75,162,067 - 75,185,882 (+)NCBIUU_Cfam_GSD_1.0
Cstf2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X63,486,186 - 63,512,707 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365846,040,336 - 6,066,703 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365846,042,785 - 6,066,758 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CSTF2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX82,508,736 - 82,540,863 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X82,508,739 - 82,540,861 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X90,379,919 - 90,409,507 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CSTF2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X89,154,895 - 89,180,783 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX89,155,771 - 89,183,551 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606514,085,220 - 14,106,442 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_004872579   ⟹   XP_004872636
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,755,308 - 1,780,826 (-)NCBI
RefSeq Acc Id: XM_004872580   ⟹   XP_004872637
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,755,308 - 1,780,825 (-)NCBI
RefSeq Acc Id: XM_013068427   ⟹   XP_012923881
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,755,308 - 1,780,826 (-)NCBI
RefSeq Acc Id: XM_021250453   ⟹   XP_021106112
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046249021,755,308 - 1,780,681 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004872636 (Get FASTA)   NCBI Sequence Viewer  
  XP_004872637 (Get FASTA)   NCBI Sequence Viewer  
  XP_012923881 (Get FASTA)   NCBI Sequence Viewer  
  XP_021106112 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB12429 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000000790
RefSeq Acc Id: XP_004872636   ⟸   XM_004872579
- Peptide Label: isoform X3
- UniProtKB: G5BT18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012923881   ⟸   XM_013068427
- Peptide Label: isoform X1
- UniProtKB: A0AAX6QRC9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004872637   ⟸   XM_004872580
- Peptide Label: isoform X4
- UniProtKB: A0AAX6QCG8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021106112   ⟸   XM_021250453
- Peptide Label: isoform X2
- UniProtKB: A0AAX6SAX2 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000000659 ENTREZGENE
Ensembl Transcript ENSHGLT00000000830 ENTREZGENE
Gene3D-CATH 1.10.20.70 UniProtKB/TrEMBL
  1.25.40.630 UniProtKB/TrEMBL
  3.30.70.330 UniProtKB/TrEMBL
InterPro CSTF2_hinge UniProtKB/TrEMBL
  CSTF_C UniProtKB/TrEMBL
  CSTF_C_sf UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
KEGG Report hgl:101718350 UniProtKB/TrEMBL
NCBI Gene Cstf2 ENTREZGENE
PANTHER CLEAVAGE STIMULATION FACTOR SUBUNIT 2 UniProtKB/TrEMBL
  PTHR45735:SF6 UniProtKB/TrEMBL
Pfam CSTF2_hinge UniProtKB/TrEMBL
  CSTF_C UniProtKB/TrEMBL
  RRM_1 UniProtKB/TrEMBL
PROSITE RRM UniProtKB/TrEMBL
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0AAX6QCG8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QRC9 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6SAX2 ENTREZGENE, UniProtKB/TrEMBL
  G5BT18 ENTREZGENE, UniProtKB/TrEMBL