Septin1 (septin 1) - Rat Genome Database

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Gene: Septin1 (septin 1) Heterocephalus glaber
Analyze
Symbol: Septin1
Name: septin 1
RGD ID: 18904252
Description: ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN meiotic metaphase chromosome alignment (ortholog); spindle assembly involved in female meiosis (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); FOUND IN meiotic spindle (ortholog); midbody (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sept1; septin-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,550,185 - 13,553,480 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,549,862 - 13,553,557 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Septin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478213,550,185 - 13,553,480 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478213,549,862 - 13,553,557 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SEPTIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381630,378,135 - 30,382,815 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1630,378,135 - 30,395,991 (-)EnsemblGRCh38hg38GRCh38
GRCh371630,389,456 - 30,394,136 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361630,296,957 - 30,301,672 (-)NCBINCBI36Build 36hg18NCBI36
Build 341630,296,957 - 30,301,672NCBI
Celera1629,904,429 - 29,909,188 (+)NCBICelera
Cytogenetic Map16p11.2NCBI
HuRef1627,951,218 - 27,955,945 (-)NCBIHuRef
CHM1_11631,706,508 - 31,711,226 (-)NCBICHM1_1
T2T-CHM13v2.01630,764,338 - 30,769,019 (-)NCBIT2T-CHM13v2.0
Septin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397126,811,881 - 126,832,157 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7126,813,619 - 126,832,302 (-)EnsemblGRCm39 Ensembl
GRCm387127,212,709 - 127,232,985 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7127,214,447 - 127,233,130 (-)EnsemblGRCm38mm10GRCm38
MGSCv377134,357,956 - 134,361,959 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367127,005,598 - 127,009,601 (-)NCBIMGSCv36mm8
Celera7127,063,210 - 127,067,214 (-)NCBICelera
Cytogenetic Map7F3NCBI
cM Map769.39NCBI
Septin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81191,263,200 - 191,267,086 (-)NCBIGRCr8
mRatBN7.21181,832,700 - 181,836,566 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1181,832,701 - 181,836,566 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1190,183,588 - 190,187,454 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01197,369,676 - 197,373,542 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01190,038,210 - 190,042,079 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01198,658,744 - 198,662,610 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1198,658,745 - 198,662,610 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01205,652,475 - 205,656,341 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,474,714 - 186,478,580 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11186,624,595 - 186,628,461 (-)NCBI
Celera1179,484,367 - 179,488,232 (-)NCBICelera
Cytogenetic Map1q37NCBI
Septin1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554937,304,472 - 7,312,185 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554937,304,472 - 7,309,022 (-)NCBIChiLan1.0ChiLan1.0
SEPTIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21833,583,330 - 33,593,399 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11638,384,787 - 38,402,163 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01624,586,711 - 24,591,587 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11630,751,869 - 30,755,133 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1630,750,665 - 30,755,345 (-)Ensemblpanpan1.1panPan2
SEPTIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1617,714,929 - 17,718,972 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl617,715,408 - 17,719,159 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha619,289,544 - 19,293,553 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0617,846,389 - 17,850,406 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl617,846,585 - 17,850,402 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1617,646,593 - 17,650,610 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0617,562,034 - 17,566,041 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0617,877,697 - 17,881,714 (+)NCBIUU_Cfam_GSD_1.0
Septin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344124,749,372 - 124,762,085 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650112,843,820 - 12,851,032 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650112,847,236 - 12,852,963 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEPTIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl317,924,651 - 17,937,947 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1317,924,651 - 17,937,949 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2318,359,300 - 18,376,616 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SEPTIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1527,055,239 - 27,059,749 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl527,055,538 - 27,059,723 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660682,461,126 - 2,465,801 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021237526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AHKG01059581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSHGLT00000016516   ⟹   ENSHGLP00000016347
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478213,550,185 - 13,553,480 (-)Ensembl
RefSeq Acc Id: XM_021237526   ⟹   XP_021093185
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478213,549,862 - 13,553,557 (-)NCBI
Protein Sequences
Protein RefSeqs XP_021093185 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_021093185   ⟸   XM_021237526
- UniProtKB: A0AAX6RBA5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000016347   ⟸   ENSHGLT00000016516


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000011715 Ensembl
Gene3D-CATH P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
InterPro G_SEPTIN_dom UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Septin UniProtKB/TrEMBL
NCBI Gene Septin1 ENTREZGENE
PANTHER SEPTIN UniProtKB/TrEMBL
Pfam Septin UniProtKB/TrEMBL
PIRSF Septin UniProtKB/TrEMBL
PROSITE G_SEPTIN UniProtKB/TrEMBL
Superfamily-SCOP P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
UniProt A0AAX6RBA5 ENTREZGENE, UniProtKB/TrEMBL