Slc8a2 (solute carrier family 8 member A2) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Slc8a2 (solute carrier family 8 member A2) Heterocephalus glaber
Analyze
Symbol: Slc8a2
Name: solute carrier family 8 member A2
RGD ID: 18904238
Description: ENCODES a protein that exhibits calcium:monoatomic cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration (ortholog); calcium:sodium antiporter activity (ortholog); sodium ion transmembrane transporter activity (ortholog); INVOLVED IN calcium ion export across plasma membrane (ortholog); calcium ion import across plasma membrane (ortholog); calcium ion transport into cytosol (ortholog); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); brain ischemia (ortholog); Reperfusion Injury (ortholog); FOUND IN cell projection (ortholog); dendrite (ortholog); dendritic spine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Sodium/calcium exchanger 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,333,677 - 6,361,888 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,333,672 - 6,359,536 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Slc8a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,333,677 - 6,361,888 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,333,672 - 6,359,536 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
SLC8A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381947,428,017 - 47,471,893 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1947,428,017 - 47,471,893 (-)EnsemblGRCh38hg38GRCh38
GRCh371947,931,274 - 47,975,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,623,735 - 52,666,934 (-)NCBINCBI36Build 36hg18NCBI36
Build 341952,623,734 - 52,666,934NCBI
Celera1944,737,047 - 44,781,071 (-)NCBICelera
Cytogenetic Map19q13.32NCBI
HuRef1944,359,692 - 44,403,467 (-)NCBIHuRef
CHM1_11947,933,461 - 47,977,474 (-)NCBICHM1_1
T2T-CHM13v2.01950,258,872 - 50,302,744 (-)NCBIT2T-CHM13v2.0
Slc8a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39715,861,540 - 15,894,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl715,863,751 - 15,894,988 (+)EnsemblGRCm39 Ensembl
GRCm38716,127,592 - 16,161,063 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl716,129,826 - 16,161,063 (+)EnsemblGRCm38mm10GRCm38
MGSCv37716,715,649 - 16,745,860 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,288,822 - 15,319,033 (+)NCBIMGSCv36mm8
Celera713,328,878 - 13,358,979 (+)NCBICelera
Cytogenetic Map7A2NCBI
cM Map78.75NCBI
Slc8a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8185,944,752 - 85,982,900 (+)NCBIGRCr8
mRatBN7.2176,816,583 - 76,852,928 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,808,725 - 76,847,072 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,196,399 - 82,220,912 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0190,760,423 - 90,784,934 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,951,488 - 83,976,005 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0178,029,555 - 78,054,042 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,025,995 - 78,060,111 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,296,259 - 79,320,746 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,473,938 - 76,498,624 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1176,552,048 - 76,576,735 (+)NCBI
Celera171,312,731 - 71,337,222 (+)NCBICelera
Cytogenetic Map1q21NCBI
Slc8a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555741,288,952 - 1,315,401 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555741,290,907 - 1,315,399 (-)NCBIChiLan1.0ChiLan1.0
SLC8A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22053,579,183 - 53,623,429 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11955,449,192 - 55,493,420 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01944,420,146 - 44,464,242 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11953,077,028 - 53,119,501 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,077,857 - 53,113,830 (-)Ensemblpanpan1.1panPan2
SLC8A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11108,544,825 - 108,575,894 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1108,544,509 - 108,575,891 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1108,026,547 - 108,056,879 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01109,070,843 - 109,101,190 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1109,070,530 - 109,101,924 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11108,737,815 - 108,768,349 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01108,382,587 - 108,412,915 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,251,103 - 109,281,451 (+)NCBIUU_Cfam_GSD_1.0
Slc8a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934919,498,414 - 19,521,451 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366641,116,491 - 1,139,586 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366641,116,543 - 1,139,586 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC8A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,201,485 - 53,236,513 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,201,477 - 53,236,489 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2648,781,798 - 48,816,809 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC8A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1640,758,106 - 40,803,277 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl640,757,440 - 40,797,126 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607320,492,681 - 20,538,539 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Sequence


Ensembl Acc Id: ENSHGLT00000025080   ⟹   ENSHGLP00000024858
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248326,333,677 - 6,361,888 (+)Ensembl
Ensembl Acc Id: ENSHGLT00000025081   ⟹   ENSHGLP00000024859
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046248326,333,677 - 6,360,016 (+)Ensembl
RefSeq Acc Id: XM_004867047   ⟹   XP_004867104
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,333,672 - 6,359,536 (+)NCBI
RefSeq Acc Id: XM_004867048   ⟹   XP_004867105
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046248326,333,672 - 6,359,536 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004867104 (Get FASTA)   NCBI Sequence Viewer  
  XP_004867105 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB00874 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000024858
  ENSHGLP00000024859
RefSeq Acc Id: XP_004867104   ⟸   XM_004867047
- Peptide Label: isoform X1
- UniProtKB: G5AV13 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004867105   ⟸   XM_004867048
- Peptide Label: isoform X2
Ensembl Acc Id: ENSHGLP00000024858   ⟸   ENSHGLT00000025080
Ensembl Acc Id: ENSHGLP00000024859   ⟸   ENSHGLT00000025081


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017722 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000025080 ENTREZGENE
  ENSHGLT00000025081 ENTREZGENE
Gene3D-CATH 1.20.1420.30 UniProtKB/TrEMBL
  2.60.40.2030 UniProtKB/TrEMBL
InterPro CaCA UniProtKB/TrEMBL
  CalX-like_sf UniProtKB/TrEMBL
  Calx_beta UniProtKB/TrEMBL
  Na_Ca_Ex UniProtKB/TrEMBL
  Na_Ca_Ex_C-exten UniProtKB/TrEMBL
  NaCa_Exmemb UniProtKB/TrEMBL
  NCX_ion-bd_dom_sf UniProtKB/TrEMBL
KEGG Report hgl:101708998 UniProtKB/TrEMBL
NCBI Gene Slc8a2 ENTREZGENE
PANTHER SODIUM/CALCIUM EXCHANGER UniProtKB/TrEMBL
  SODIUM/CALCIUM EXCHANGER 2 UniProtKB/TrEMBL
Pfam Calx-beta UniProtKB/TrEMBL
  Na_Ca_ex UniProtKB/TrEMBL
  Na_Ca_ex_C UniProtKB/TrEMBL
PRINTS NACAEXCHNGR UniProtKB/TrEMBL
SMART Calx_beta UniProtKB/TrEMBL
Superfamily-SCOP SSF141072 UniProtKB/TrEMBL
UniProt G5AV13 ENTREZGENE, UniProtKB/TrEMBL