Pik3r6 (phosphoinositide-3-kinase regulatory subunit 6) - Rat Genome Database

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Gene: Pik3r6 (phosphoinositide-3-kinase regulatory subunit 6) Heterocephalus glaber
Analyze
Symbol: Pik3r6
Name: phosphoinositide-3-kinase regulatory subunit 6
RGD ID: 18904226
Description: ENCODES a protein that exhibits 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (ortholog); INVOLVED IN positive regulation of angiogenesis (ortholog); positive regulation of T cell differentiation (ortholog); regulation of natural killer cell mediated cytotoxicity (ortholog); PARTICIPATES IN eicosanoid signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; insulin signaling pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN membrane (ortholog); phosphatidylinositol 3-kinase complex, class IA (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoinositide 3-kinase regulatory subunit 6
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478611,326,364 - 11,371,767 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478611,324,558 - 11,386,202 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Pik3r6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478611,326,364 - 11,371,767 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462478611,324,558 - 11,386,202 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
PIK3R6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38178,802,722 - 8,867,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl178,802,722 - 8,867,677 (-)EnsemblGRCh38hg38GRCh38
GRCh37178,706,040 - 8,770,994 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,646,780 - 8,711,719 (-)NCBINCBI36Build 36hg18NCBI36
Build 34178,647,316 - 8,683,739NCBI
Celera178,736,925 - 8,802,828 (-)NCBICelera
Cytogenetic Map17p13.1NCBI
HuRef178,605,017 - 8,670,244 (-)NCBIHuRef
CHM1_1178,715,147 - 8,780,110 (-)NCBICHM1_1
T2T-CHM13v2.0178,708,926 - 8,774,833 (-)NCBIT2T-CHM13v2.0
Pik3r6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391168,393,845 - 68,443,524 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1168,393,845 - 68,443,524 (+)EnsemblGRCm39 Ensembl
GRCm381168,503,019 - 68,552,698 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1168,503,019 - 68,552,698 (+)EnsemblGRCm38mm10GRCm38
MGSCv371168,316,521 - 68,366,200 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361168,319,286 - 68,368,893 (+)NCBIMGSCv36mm8
Celera1175,440,292 - 75,489,918 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1141.76NCBI
Pik3r6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81053,702,821 - 53,754,113 (+)NCBIGRCr8
mRatBN7.21053,203,930 - 53,255,229 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1053,205,496 - 53,255,243 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1057,881,076 - 57,914,437 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01057,370,116 - 57,403,475 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01052,878,871 - 52,912,377 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01055,085,269 - 55,135,069 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1055,085,259 - 55,135,092 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01054,829,255 - 54,879,028 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41055,270,065 - 55,303,503 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1052,389,252 - 52,422,664 (+)NCBICelera
Cytogenetic Map10q24NCBI
Pik3r6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554678,104,906 - 8,157,144 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554678,104,242 - 8,157,637 (+)NCBIChiLan1.0ChiLan1.0
PIK3R6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21964,891,181 - 64,946,495 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11769,700,506 - 69,755,779 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01742,782,422 - 42,851,692 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11747,518,629 - 47,585,160 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1747,518,629 - 47,585,160 (+)Ensemblpanpan1.1panPan2
PIK3R6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1533,472,240 - 33,528,369 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl533,472,771 - 33,528,400 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha533,608,573 - 33,664,684 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0533,575,473 - 33,631,553 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl533,575,457 - 33,631,578 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1533,543,177 - 33,599,204 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0533,500,676 - 33,556,758 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0533,677,115 - 33,733,252 (-)NCBIUU_Cfam_GSD_1.0
Pik3r6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560248,479,138 - 48,512,137 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365951,953,375 - 1,986,150 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365951,953,372 - 1,983,765 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3R6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1253,906,511 - 53,964,514 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11253,910,999 - 53,971,088 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21256,661,528 - 56,723,760 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3R6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1168,158,842 - 8,224,192 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl168,159,400 - 8,223,937 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605913,158,022 - 13,223,797 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000021216   ⟹   ENSHGLP00000021013
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462478611,326,364 - 11,371,767 (-)Ensembl
RefSeq Acc Id: XM_004857512   ⟹   XP_004857569
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478611,324,558 - 11,386,202 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004857569 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000021013
Reference Protein Sequences
RefSeq Acc Id: XP_004857569   ⟸   XM_004857512
- UniProtKB: G5B5G6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000021013   ⟸   ENSHGLT00000021216


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015017 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000021216 ENTREZGENE
InterPro PIK3R5/6 UniProtKB/TrEMBL
NCBI Gene Pik3r6 ENTREZGENE
PANTHER PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT UniProtKB/TrEMBL
  PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 6 UniProtKB/TrEMBL
Pfam PI3K_1B_p101 UniProtKB/TrEMBL
UniProt G5B5G6 ENTREZGENE, UniProtKB/TrEMBL