Ube4a (ubiquitination factor E4A) - Rat Genome Database

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Gene: Ube4a (ubiquitination factor E4A) Heterocephalus glaber
Analyze
Symbol: Ube4a
Name: ubiquitination factor E4A
RGD ID: 18904011
Description: ENCODES a protein that exhibits ubiquitin protein ligase activity (ortholog); INVOLVED IN protein polyubiquitination (ortholog); ASSOCIATED WITH CD3epsilon deficiency (ortholog); Chromosome 11, Partial Trisomy 11q (ortholog); Dwarfism (ortholog); FOUND IN cytoplasm (inferred); nucleus (inferred); ubiquitin ligase complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ubiquitin conjugation factor E4 A
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478413,754,234 - 13,792,616 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:21993625   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ube4a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478413,754,234 - 13,792,616 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
UBE4A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,359,600 - 118,399,211 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11118,359,600 - 118,399,211 (+)EnsemblGRCh38hg38GRCh38
GRCh3711118,230,315 - 118,269,926 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,735,512 - 117,775,136 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411117,735,511 - 117,775,134NCBI
Celera11115,388,170 - 115,427,789 (+)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,164,298 - 114,204,054 (+)NCBIHuRef
CHM1_111118,116,796 - 118,156,382 (+)NCBICHM1_1
T2T-CHM13v2.011118,375,859 - 118,415,462 (+)NCBIT2T-CHM13v2.0
Ube4a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,834,425 - 44,877,021 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,834,425 - 44,876,898 (-)EnsemblGRCm39 Ensembl
GRCm38944,923,127 - 44,965,615 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,923,127 - 44,965,600 (-)EnsemblGRCm38mm10GRCm38
MGSCv37944,731,210 - 44,773,683 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36944,684,066 - 44,716,520 (-)NCBIMGSCv36mm8
Celera942,188,425 - 42,230,712 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
Ube4a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8854,132,799 - 54,174,921 (-)NCBIGRCr8
mRatBN7.2845,236,022 - 45,278,129 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl845,236,026 - 45,278,038 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx850,731,379 - 50,773,216 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0849,010,100 - 49,051,937 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,880,680 - 46,922,496 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0849,229,713 - 49,271,894 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl849,229,717 - 49,271,834 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0847,847,865 - 47,889,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4847,879,266 - 47,918,955 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1847,888,031 - 47,927,727 (-)NCBI
Celera844,820,845 - 44,860,533 (-)NCBICelera
Cytogenetic Map8q22NCBI
Ube4a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541219,516,691 - 19,553,773 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541219,517,182 - 19,551,503 (+)NCBIChiLan1.0ChiLan1.0
UBE4A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,060,507 - 119,100,203 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,165,574 - 120,205,255 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,193,986 - 113,233,660 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,125,582 - 117,162,518 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,131,100 - 117,162,385 (+)Ensemblpanpan1.1panPan2
UBE4A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1515,338,279 - 15,375,722 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl515,341,141 - 15,370,294 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha515,389,033 - 15,426,486 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0515,280,409 - 15,318,046 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl515,280,447 - 15,317,969 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1515,418,864 - 15,456,318 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0515,322,601 - 15,359,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0515,363,227 - 15,400,919 (-)NCBIUU_Cfam_GSD_1.0
UBE4A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl945,661,106 - 45,704,810 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1945,661,090 - 45,701,911 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2950,702,219 - 50,743,041 (+)NCBISscrofa10.2Sscrofa10.2susScr3
UBE4A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11109,735,778 - 109,776,629 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1109,735,752 - 109,776,661 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604316,258,929 - 16,299,903 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_004856697   ⟹   XP_004856754
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462478413,754,234 - 13,792,616 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004856754 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EHB08777 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000025008
  ENSHGLP00100038623
Reference Protein Sequences
RefSeq Acc Id: XP_004856754   ⟸   XM_004856697
- UniProtKB: G5BHL6 (UniProtKB/TrEMBL)


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000017823 ENTREZGENE
  ENSHGLG00100014069 UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000025230 ENTREZGENE
  ENSHGLT00100090634 UniProtKB/TrEMBL
Gene3D-CATH 3.30.40.10 UniProtKB/TrEMBL
InterPro Ub_conjug_fac_E4_core UniProtKB/TrEMBL
  UBE4 UniProtKB/TrEMBL
  Ubox_domain UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
KEGG Report hgl:101711837 UniProtKB/TrEMBL
NCBI Gene Ube4a ENTREZGENE
PANTHER PTHR13931 UniProtKB/TrEMBL
  UBIQUITIN CONJUGATION FACTOR E4 A UniProtKB/TrEMBL
Pfam U-box UniProtKB/TrEMBL
  Ufd2P_core UniProtKB/TrEMBL
PROSITE U_BOX UniProtKB/TrEMBL
SMART Ubox UniProtKB/TrEMBL
Superfamily-SCOP RING/U-box UniProtKB/TrEMBL
UniProt G5BHL6 ENTREZGENE, UniProtKB/TrEMBL