Ephb1 (EPH receptor B1) - Rat Genome Database

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Gene: Ephb1 (EPH receptor B1) Heterocephalus glaber
Analyze
Symbol: Ephb1
Name: EPH receptor B1
RGD ID: 18903912
Description: ENCODES a protein that exhibits axon guidance receptor activity (ortholog); protein tyrosine kinase activity (ortholog); protein-containing complex binding (ortholog); INVOLVED IN angiogenesis (ortholog); axon guidance (ortholog); camera-type eye morphogenesis (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectional signaling axis; ASSOCIATED WITH aortic dissection (ortholog); COVID-19 (ortholog); genetic disease (ortholog); FOUND IN axon (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: ephrin type-B receptor 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473011,119,909 - 11,565,293 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473011,120,018 - 11,564,972 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ephb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473011,119,909 - 11,565,293 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473011,120,018 - 11,564,972 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
EPHB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383134,795,260 - 135,260,467 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3134,795,260 - 135,260,467 (+)EnsemblGRCh38hg38GRCh38
GRCh373134,514,102 - 134,979,309 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363135,996,950 - 136,461,999 (+)NCBINCBI36Build 36hg18NCBI36
Build 343135,996,957 - 136,462,003NCBI
Celera3132,940,535 - 133,405,242 (+)NCBICelera
Cytogenetic Map3q22.2NCBI
HuRef3131,890,822 - 132,356,715 (+)NCBIHuRef
CHM1_13134,478,274 - 134,942,745 (+)NCBICHM1_1
T2T-CHM13v2.03137,540,631 - 138,005,927 (+)NCBIT2T-CHM13v2.0
Ephb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399101,799,327 - 102,231,892 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9101,799,327 - 102,231,892 (-)EnsemblGRCm39 Ensembl
GRCm389101,922,128 - 102,354,693 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9101,922,128 - 102,354,693 (-)EnsemblGRCm38mm10GRCm38
MGSCv379101,824,458 - 102,257,023 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369101,778,391 - 102,210,896 (-)NCBIMGSCv36mm8
Celera9101,458,328 - 101,902,746 (-)NCBICelera
Cytogenetic Map9F1NCBI
cM Map954.15NCBI
Ephb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88111,386,432 - 111,823,759 (-)NCBIGRCr8
mRatBN7.28102,507,549 - 102,944,839 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8102,507,549 - 102,944,839 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8108,174,355 - 108,610,838 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08106,373,671 - 106,810,017 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08104,216,189 - 104,652,675 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08110,376,954 - 110,813,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8110,376,954 - 110,813,000 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08109,782,848 - 110,218,328 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48106,871,856 - 107,328,156 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18106,892,184 - 107,347,611 (-)NCBI
Celera8101,892,152 - 102,327,473 (-)NCBICelera
Cytogenetic Map8q32NCBI
Ephb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555013,423,977 - 3,821,890 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555013,424,112 - 3,821,727 (-)NCBIChiLan1.0ChiLan1.0
EPHB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22132,721,019 - 133,188,676 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13132,725,745 - 133,193,405 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03131,841,459 - 132,309,082 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13139,312,933 - 139,778,166 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3139,313,387 - 139,776,802 (+)Ensemblpanpan1.1panPan2
EPHB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12331,485,701 - 31,918,754 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2331,485,534 - 31,917,393 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2331,423,133 - 31,897,303 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02332,297,984 - 32,440,415 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2332,322,030 - 32,439,750 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12331,656,516 - 32,130,657 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02331,717,030 - 32,191,562 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02331,963,973 - 32,438,568 (+)NCBIUU_Cfam_GSD_1.0
Ephb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560271,079,838 - 71,501,438 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365297,839,768 - 8,261,942 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365298,006,780 - 8,261,923 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EPHB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1375,905,676 - 76,345,534 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11375,904,678 - 76,351,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21383,511,907 - 83,816,698 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EPHB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11555,144,178 - 55,592,252 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1555,143,630 - 55,589,862 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604128,194,516 - 28,305,649 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000019191   ⟹   ENSHGLP00000019002
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473011,119,909 - 11,565,293 (+)Ensembl
RefSeq Acc Id: ENSHGLT00000019192   ⟹   ENSHGLP00000019003
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462473011,120,466 - 11,563,653 (+)Ensembl
RefSeq Acc Id: XM_004834274   ⟹   XP_004834331
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473011,120,019 - 11,564,972 (+)NCBI
RefSeq Acc Id: XM_013070768   ⟹   XP_012926222
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473011,120,018 - 11,564,972 (+)NCBI
RefSeq Acc Id: XM_013070773   ⟹   XP_012926227
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462473011,120,018 - 11,564,972 (+)NCBI
Protein Sequences
Protein RefSeqs XP_004834331 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926222 (Get FASTA)   NCBI Sequence Viewer  
  XP_012926227 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000019002
Reference Protein Sequences
RefSeq Acc Id: XP_012926222   ⟸   XM_013070768
- Peptide Label: isoform X2
- UniProtKB: G5BL12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012926227   ⟸   XM_013070773
- Peptide Label: isoform X3
- UniProtKB: G5BL12 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004834331   ⟸   XM_004834274
- Peptide Label: isoform X1
- UniProtKB: G5BL12 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000019003   ⟸   ENSHGLT00000019192
RefSeq Acc Id: ENSHGLP00000019002   ⟸   ENSHGLT00000019191


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000013616 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000019191 ENTREZGENE
Gene3D-CATH ephrin a2 ectodomain UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Immunoglobulins UniProtKB/TrEMBL
  Transcription Factor, Ets-1 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
  Tumor Necrosis Factor Receptor, subunit A, domain 2 UniProtKB/TrEMBL
InterPro Eph_TM UniProtKB/TrEMBL
  EphB1_SAM UniProtKB/TrEMBL
  Ephrin_rcpt_lig-bd_dom UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Galactose-bd-like_sf UniProtKB/TrEMBL
  Growth_fac_rcpt_cys_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
  Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Tyr_kinase_ephrin_rcpt UniProtKB/TrEMBL
  Tyr_kinase_rcpt_V_CS UniProtKB/TrEMBL
NCBI Gene Ephb1 ENTREZGENE
PANTHER EPH RECEPTOR A5 UniProtKB/TrEMBL
  EPHRIN TYPE-B RECEPTOR 1 UniProtKB/TrEMBL
Pfam EphA2_TM UniProtKB/TrEMBL
  Ephrin_lbd UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
  PK_Tyr_Ser-Thr UniProtKB/TrEMBL
  SAM_1 UniProtKB/TrEMBL
PIRSF TyrPK_ephrin_receptor UniProtKB/TrEMBL
PRINTS FNTYPEIII UniProtKB/TrEMBL
  TYRKINASE UniProtKB/TrEMBL
PROSITE EPH_LBD UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_1 UniProtKB/TrEMBL
  RECEPTOR_TYR_KIN_V_2 UniProtKB/TrEMBL
  SAM_DOMAIN UniProtKB/TrEMBL
SMART EPH_lbd UniProtKB/TrEMBL
  Ephrin_rec_like UniProtKB/TrEMBL
  FN3 UniProtKB/TrEMBL
  SAM UniProtKB/TrEMBL
  TyrKc UniProtKB/TrEMBL
Superfamily-SCOP Fibronectin type III UniProtKB/TrEMBL
  Galactose-binding domain-like UniProtKB/TrEMBL
  Growth factor receptor domain UniProtKB/TrEMBL
  Protein kinase-like (PK-like) UniProtKB/TrEMBL
  SAM/Pointed domain UniProtKB/TrEMBL
UniProt G5BL12 ENTREZGENE, UniProtKB/TrEMBL