Adgrb2 (adhesion G protein-coupled receptor B2) - Rat Genome Database

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Gene: Adgrb2 (adhesion G protein-coupled receptor B2) Heterocephalus glaber
Analyze
Symbol: Adgrb2
Name: adhesion G protein-coupled receptor B2
RGD ID: 18903512
Description: ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); INVOLVED IN calcineurin-NFAT signaling cascade (ortholog); peripheral nervous system development (ortholog); positive regulation of synapse assembly (ortholog); ASSOCIATED WITH COVID-19 (ortholog); hereditary spastic paraplegia (ortholog); Spastic Paraparesis (ortholog); FOUND IN glutamatergic synapse (ortholog); synapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Bai2; brain-specific angiogenesis inhibitor 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476414,964,480 - 15,001,320 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476414,964,614 - 15,001,429 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Adgrb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476414,964,480 - 15,001,320 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476414,964,614 - 15,001,429 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
ADGRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38131,727,117 - 31,764,340 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl131,727,117 - 31,764,893 (-)EnsemblGRCh38hg38GRCh38
GRCh37132,192,718 - 32,229,941 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36131,965,305 - 32,002,235 (-)NCBINCBI36Build 36hg18NCBI36
Build 34131,861,811 - 31,898,729NCBI
Celera130,461,955 - 30,498,884 (-)NCBICelera
Cytogenetic Map1p35.2NCBI
HuRef130,310,212 - 30,346,996 (-)NCBIHuRef
CHM1_1132,308,513 - 32,345,443 (-)NCBICHM1_1
T2T-CHM13v2.0131,584,757 - 31,621,990 (-)NCBIT2T-CHM13v2.0
Adgrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394129,878,566 - 129,916,426 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4129,878,663 - 129,916,426 (+)EnsemblGRCm39 Ensembl
GRCm384129,984,773 - 130,022,633 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4129,984,870 - 130,022,633 (+)EnsemblGRCm38mm10GRCm38
MGSCv374129,662,408 - 129,699,877 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364129,494,372 - 129,524,652 (+)NCBIMGSCv36mm8
Celera4128,319,684 - 128,357,331 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map463.43NCBI
Adgrb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85147,581,573 - 147,646,726 (+)NCBIGRCr8
mRatBN7.25142,299,190 - 142,362,540 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5142,331,329 - 142,362,540 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5145,032,526 - 145,063,767 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05146,802,347 - 146,833,584 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05146,799,866 - 146,831,097 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05148,168,530 - 148,231,587 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5148,193,710 - 148,231,587 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05151,888,166 - 151,950,961 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45149,014,053 - 149,046,244 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15149,017,386 - 149,056,274 (+)NCBI
Celera5140,800,108 - 140,831,213 (+)NCBICelera
Cytogenetic Map5q36NCBI
Adgrb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545210,131,371 - 10,167,597 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545210,131,371 - 10,167,597 (-)NCBIChiLan1.0ChiLan1.0
ADGRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21195,065,768 - 195,102,744 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11194,187,456 - 194,224,391 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0131,010,807 - 31,047,780 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1132,028,239 - 32,065,277 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl132,028,554 - 32,060,582 (-)Ensemblpanpan1.1panPan2
ADGRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1269,353,425 - 69,389,256 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl269,353,413 - 69,389,225 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha265,932,620 - 65,968,435 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0269,918,691 - 69,954,503 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl269,918,648 - 69,954,496 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1266,754,617 - 66,790,423 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0267,750,754 - 67,786,570 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0268,750,286 - 68,786,095 (+)NCBIUU_Cfam_GSD_1.0
Adgrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505849,010,839 - 49,046,033 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647414,835,602 - 14,870,821 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647414,835,621 - 14,870,815 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADGRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl688,256,146 - 88,293,330 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1688,256,144 - 88,293,519 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2681,956,153 - 81,986,674 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADGRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120101,107,561 - 101,144,359 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20101,081,197 - 101,295,467 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603315,546,820 - 15,583,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000027081   ⟹   ENSHGLP00000026842
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,964,480 - 15,001,320 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027082   ⟹   ENSHGLP00000026843
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,964,480 - 14,994,584 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027083   ⟹   ENSHGLP00000026844
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,964,916 - 14,994,780 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027084   ⟹   ENSHGLP00000026845
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,964,916 - 14,994,227 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027085   ⟹   ENSHGLP00000026846
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,964,916 - 14,994,227 (-)Ensembl
Ensembl Acc Id: ENSHGLT00000027086   ⟹   ENSHGLP00000026847
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_00462476414,964,916 - 14,994,227 (-)Ensembl
RefSeq Acc Id: XM_013074306   ⟹   XP_012929760
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,916 - 15,001,429 (-)NCBI
RefSeq Acc Id: XM_013074308   ⟹   XP_012929762
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 15,001,428 (-)NCBI
RefSeq Acc Id: XM_021263240   ⟹   XP_021118899
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,916 - 15,001,429 (-)NCBI
RefSeq Acc Id: XM_021263241   ⟹   XP_021118900
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 14,994,227 (-)NCBI
RefSeq Acc Id: XM_021263242   ⟹   XP_021118901
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 14,994,227 (-)NCBI
RefSeq Acc Id: XM_021263244   ⟹   XP_021118903
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 14,994,227 (-)NCBI
RefSeq Acc Id: XM_021263245   ⟹   XP_021118904
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 14,994,227 (-)NCBI
RefSeq Acc Id: XM_021263246   ⟹   XP_021118905
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,916 - 14,994,227 (-)NCBI
RefSeq Acc Id: XM_021263247   ⟹   XP_021118906
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 15,001,428 (-)NCBI
RefSeq Acc Id: XM_021263248   ⟹   XP_021118907
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,916 - 14,994,227 (-)NCBI
RefSeq Acc Id: XM_021263249   ⟹   XP_021118908
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_00462476414,964,614 - 14,994,227 (-)NCBI
RefSeq Acc Id: XP_012929762   ⟸   XM_013074308
- Peptide Label: isoform X9
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6R002 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118906   ⟸   XM_021263247
- Peptide Label: isoform X6
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TAM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118908   ⟸   XM_021263249
- Peptide Label: isoform X8
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TDC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118904   ⟸   XM_021263245
- Peptide Label: isoform X4
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TEJ5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118903   ⟸   XM_021263244
- Peptide Label: isoform X3
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TFQ0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118901   ⟸   XM_021263242
- Peptide Label: isoform X2
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TCI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118900   ⟸   XM_021263241
- Peptide Label: isoform X1
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TGG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118899   ⟸   XM_021263240
- Peptide Label: isoform X1
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TGG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012929760   ⟸   XM_013074306
- Peptide Label: isoform X1
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TGG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118905   ⟸   XM_021263246
- Peptide Label: isoform X5
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6TBC0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021118907   ⟸   XM_021263248
- Peptide Label: isoform X7
- UniProtKB: G5BUA1 (UniProtKB/TrEMBL),   A0AAX6T9G0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000026842   ⟸   ENSHGLT00000027081
Ensembl Acc Id: ENSHGLP00000026843   ⟸   ENSHGLT00000027082
Ensembl Acc Id: ENSHGLP00000026846   ⟸   ENSHGLT00000027085
Ensembl Acc Id: ENSHGLP00000026847   ⟸   ENSHGLT00000027086
Ensembl Acc Id: ENSHGLP00000026844   ⟸   ENSHGLT00000027083
Ensembl Acc Id: ENSHGLP00000026845   ⟸   ENSHGLT00000027084


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000019091 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000027081 ENTREZGENE
  ENSHGLT00000027082 ENTREZGENE
  ENSHGLT00000027083 ENTREZGENE
  ENSHGLT00000027085 ENTREZGENE
  ENSHGLT00000027086 ENTREZGENE
Gene3D-CATH 1.25.40.610 UniProtKB/TrEMBL
  2.60.220.50 UniProtKB/TrEMBL
  GPCR, family 2, extracellular hormone receptor domain UniProtKB/TrEMBL
  Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
  Thrombospondin type-1 (TSP1) repeat UniProtKB/TrEMBL
InterPro AGRB_N UniProtKB/TrEMBL
  Angio_Inhib/Adhesion_GPCR UniProtKB/TrEMBL
  GAIN_dom_N UniProtKB/TrEMBL
  GAIN_dom_sf UniProtKB/TrEMBL
  GPCR_2-like_TM UniProtKB/TrEMBL
  GPCR_2_brain_angio_inhib UniProtKB/TrEMBL
  GPCR_2_extracell_dom_sf UniProtKB/TrEMBL
  GPCR_2_extracellular_dom UniProtKB/TrEMBL
  GPCR_2_secretin-like UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  TSP1_rpt UniProtKB/TrEMBL
  TSP1_rpt_sf UniProtKB/TrEMBL
NCBI Gene Adgrb2 ENTREZGENE
PANTHER ADHESION G PROTEIN-COUPLED RECEPTOR B2 UniProtKB/TrEMBL
  ISTHMIN-2 UniProtKB/TrEMBL
Pfam 7tm_2 UniProtKB/TrEMBL
  AGRB_N UniProtKB/TrEMBL
  GAIN UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  HRM UniProtKB/TrEMBL
  TSP_1 UniProtKB/TrEMBL
PRINTS BAIPRECURSOR UniProtKB/TrEMBL
  GPCRSECRETIN UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F2_3 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F2_4 UniProtKB/TrEMBL
  GPS UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
SMART GPS UniProtKB/TrEMBL
  HormR UniProtKB/TrEMBL
  TSP1 UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
  TSP-1 type 1 repeat UniProtKB/TrEMBL
UniProt A0AAX6R002 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6T9G0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TAM1 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TBC0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TCI5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TDC0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TEJ5 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TFQ0 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TGG9 ENTREZGENE, UniProtKB/TrEMBL
  G5BUA1 ENTREZGENE, UniProtKB/TrEMBL